Journal article
Effect of substrate and fibrin polymerization inhibitor on determination of plasma thrombin generation in vitro
Abstract
BACKGROUND: Thrombin generation potential, a critical haemostatic measure, can be determined by continuous detection of total thrombin or direct subsampling. However, differences between methods exist in area under the curve or peak thrombin calculated. Also, impact of anticoagulants on thrombin generation may vary depending on mode of analysis.
OBJECTIVE: We studied the effect of components on thrombin generation in the presence or absence of …
Authors
Lau A; Berry LR; Mitchell LG; Chan AKC
Journal
Thrombosis Research, Vol. 119, No. 6, pp. 667–677
Publisher
Elsevier
Publication Date
1 2007
DOI
10.1016/j.thromres.2006.05.008
ISSN
0049-3848