Journal article
Thrombin activation rate constant: One-stage chromogenic assay for the extrinsic system
Abstract
Some properties of a one-stage, chromogenic clotting assay using tissue thromboplastin as an activator are described. The chromogenic assay uses S-2238 as substrate and estimates thrombin by the rate of absorbance produced. Under assay conditions, it was observed that the log (thrombin or absorbance/min) is linear with time. The linearity appeared to extend from zero thrombin up to maximum thrombin concentration for all concentrations of each …
Authors
Baughman DJ; Lytwyn A
Journal
Thrombosis Research, Vol. 26, No. 1, pp. 1–12
Publisher
Elsevier
Publication Date
April 1982
DOI
10.1016/0049-3848(82)90145-1
ISSN
0049-3848