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Adsorption of thrombin from buffer and modified...
Journal article

Adsorption of thrombin from buffer and modified plasma to polystyrene resins containing sulphonate and sulphamide arginyl methyl ester groups

Abstract

The adsorption of albumin and thrombin to insoluble modified polystyrene resins bearing sulphonate (PSSO3) and L-arginyl methyl ester groups (PAOM) was investigated in both purified and plasma systems. Radioiodinated proteins were used to follow adsorption in a 'minicolumn' experiment. Albumin adsorption was found to follow the Langmuir model and specific surface areas of the various resins were evaluated from plateau albumin adsorption data. …

Authors

Boisson C; Jozefonvicz J; Brash JL

Journal

Biomaterials, Vol. 9, No. 1, pp. 47–52

Publisher

Elsevier

Publication Date

January 1988

DOI

10.1016/0142-9612(88)90068-3

ISSN

0142-9612