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Effects of Sulfated Polysaccharides on Inhibition...
Journal article

Effects of Sulfated Polysaccharides on Inhibition of Thrombus Formation initiated by Different Stimuli

Abstract

To test the possibility that different doses of heparin or other sulfated polysaccharides are required to inhibit thrombosis initiated by different stimuli, we compared the effects of heparin (HEP), pentosan polysulfate (SP54) and dermatan sulfate (DS) on the inhibition of thrombus formation induced by either I) tissue thromboplastin; II) thrombin; or III) factor Xa. Inhibition of thrombus formation induced by the stimuli was measured in a …

Authors

Ryn-McKenna JV; Gray E; Weber E; Ofosu FA; Buchanan MR

Journal

Thrombosis and Haemostasis, Vol. 61, No. 01, pp. 007–009

Publisher

Thieme

Publication Date

1989

DOI

10.1055/s-0038-1646517

ISSN

0340-6245