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The Inhibitory Effects of Exogenous Arachidonic...
Journal article

The Inhibitory Effects of Exogenous Arachidonic Acid on Rabbit Platelet Aggregation and the Release Reaction

Abstract

Abstract Although arachidonic acid causes rabbit platelet aggregation and the release of granule contents in suspensions of washed platelets when used in concentrations of approximately 50–300 microM, higher concentrations (500 microM) cause neither aggregation nor release. Suspensions of platelets from rabbits wee exposed to arachidonic acid (250 microM) for 15 min, allowed to recover in the presence of PGE1 for 30 min, …

Authors

Cattaneo M; Kinlough-Rathbone RL; Perry DW; Chahil A; Vickers JD; Lam SC-T; Packham MA; Mustard JF

Journal

Blood, Vol. 60, No. 5, pp. 1179–1187

Publisher

American Society of Hematology

Publication Date

November 1, 1982

DOI

10.1182/blood.v60.5.1179.1179

ISSN

0006-4971