Journal article
The inhibition of the anticoagulant activity of heparin by platelets, brain phospholipids, and tissue factor
Abstract
Platelets and phospholipids have been shown to protect factor Xa from inhibition by the heparin--antithrombin III complex. The studies reported herein investigated the effects of gel filtered platelets, activated platelets, brain phospholipids (cephalin), and brain tissue factor on the inactivation of thrombin and factor Xa by the heparin--antithrombin III complex. In addition, the relative anticoagulant effects of heparin on the extrinsic and …
Authors
Ofosu FA; Cerskus AL; Hirsh J; Smith LM; Modi GJ; Blajchman MA
Journal
British Journal of Haematology, Vol. 57, No. 2, pp. 229–238
Publisher
Wiley
Publication Date
June 1984
DOI
10.1111/j.1365-2141.1984.tb02891.x
ISSN
0007-1048