Journal article
Heparan Sulfate and Dermatan Sulfate Inhibit the Generation of Thrombin Activity in Plasma by Complementary Pathways
Abstract
Abstract
Heparan with a low affinity for antithrombin III has previously been demonstrated to inhibit thrombin generation in both normal plasma and plasma depleted of antithrombin III. In addition, standard heparin and heparin with a low affinity for antithrombin III have been demonstrated to have equivalent inhibitory actions on thrombin generation in plasma depleted of antithrombin III. These observations prompted the …
Authors
Ofosu FA; Modi GJ; Smith LM; Cerskus AL; Hirsh J; Blajchman MA
Journal
Blood, Vol. 64, No. 3, pp. 742–747
Publisher
American Society of Hematology
Publication Date
September 1, 1984
DOI
10.1182/blood.v64.3.742.742
ISSN
0006-4971