Prognostic utility and characterization of cell-free DNA in patients with severe sepsis

IntroductionAlthough sepsis is the leading cause of death in noncoronary critically ill patients, identification of patients at high risk of death remains a challenge. In this study, we examined the incremental usefulness of adding multiple biomarkers to clinical scoring systems for predicting intensive care unit (ICU) mortality in patients with severe sepsis.MethodsThis retrospective observational study used stored plasma samples obtained from …