Journal article
Effects of Thrombin and the Thrombin Receptor Activating Peptide, SFLLRN, on Redistribution of Platelet α-Granule Contents Are Similar and Independent of the Extent of Thromboxane Formation
Abstract
Immunocytochemistry with gold-labeled antibodies was used to compare the effects of stimulation of human platelets with thrombin (1 U/ml) and the thrombin receptor activating peptide, SFLLRN (20 microM). After 3 min, redistribution of fibrinogen, von Willebrand factor, and P-selectin (GMP-140, CD62) was examined, the percentages of [14C]serotonin and beta-thromboglobulin released from pre-labeled platelets were measured, and the amount of …
Authors
Suzuki H; Packham MA; Kinlough-Rathbone RL
Journal
Experimental and Molecular Pathology, Vol. 62, No. 1, pp. 63–72
Publisher
Elsevier
Publication Date
February 1995
DOI
10.1006/exmp.1995.1007
ISSN
0014-4800