Journal article
Prolonged Expression of Procoagulant Activity of Human Platelets Degranulated by Thrombin
Abstract
Platelets are exposed to thrombin when they take part in arterial thrombus formation, and they may return to the circulation when they are freed by fibrinolysis and dislodged by flowing blood. Thrombin causes the expression of procoagulant activity on platelets, and if this activity persists, the recirculating platelets may contribute to subsequent thrombosis. We have developed techniques to degranulate human platelets by treatment with …
Authors
Kinlough-Rathbone RL; Perry DW
Journal
Thrombosis and Haemostasis, Vol. 74, No. 03, pp. 958–961
Publisher
Thieme
Publication Date
1995
DOI
10.1055/s-0038-1649855
ISSN
0340-6245