Journal article
Thrombin generation abnormalities in commonly encountered platelet function disorders
Abstract
INTRODUCTION: Studies of thrombin generation (TG) with platelet-rich plasma (PRP) and platelet-poor plasma (PPP) have provided insights on bleeding disorders. We studied TG for a cohort with commonly encountered platelet function disorders (PFD).
METHODS: Participants included 40 controls and 31 with PFD due to: nonsyndromic dense granule (DG) deficiency (PFD-DGD, n = 9), RUNX1 haploinsufficiency (n = 6) and aggregation defects from other, …
Authors
Sharma T; Brunet JG; Tasneem S; Smith SA; Morrissey JH; Hayward CPM
Journal
International Journal of Laboratory Hematology, Vol. 43, No. 6, pp. 1557–1565
Publisher
Wiley
Publication Date
December 2021
DOI
10.1111/ijlh.13638
ISSN
1751-5521