New Anticoagulant Therapy Journal Articles

abstract

• The development of new anticoagulants is expanding the list of drugs that can be used to prevent and treat venous and arterial thrombosis. New parenteral anticoagulants have been developed to overcome the limitations of heparin and low-molecular-weight heparin, whereas novel orally active anticoagulants have been designed to provide more streamlined therapy than vitamin K antagonists. This review identifies the molecular targets of new anticoagulants, describes the results of clinical trials, and provides clinical perspective on the opportunities for new anticoagulants.

authors

• Linkins, Lori-ann
• Weitz, Jeffrey

status

• published 

publication date

• February 1, 2005

has subject area

• 1103 Clinical Sciences (FoR)
• Administration, Oral (MeSH)
• Anticoagulants (MeSH)
• Antithrombin III (MeSH)
• Clinical Trials as Topic (MeSH)
• Drugs, Investigational (MeSH)
• Factor VIIIa (MeSH)
• Factor VIIa (MeSH)
• Factor Va (MeSH)
• General & Internal Medicine (Science Metrix)
• Humans (MeSH)
• Lipoproteins (MeSH)
• Thrombin (MeSH)
• Thrombosis (MeSH)

published in

• Annual Review of Medicine  Journal

keywords

• Administration, Oral
• Anticoagulants
• Antithrombin III
• Clinical Trials as Topic
• Drugs, Investigational
• Factor VIIIa
• Factor VIIa
• Factor Va
• Humans
• Lipoproteins
• Thrombin
• Thrombosis

Digital Object Identifier (DOI)

• 10.1146/annurev.med.56.082103.104708

PubMed ID

• 15660502

start page

• 63

end page

• 77

volume

• 56

issue

• 1