Contrasting Effects of Thrombin and the Thrombin Receptor Peptide, SFLLRN, on Aggregation and Release of 14C-Serotonin by Human Platelets Pretreated with Chymotrypsin or Serratia marcescens Protease Article uri icon

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abstract

  • Download Citation on ResearchGate \textbar Contrasting Effects of Thrombin and the Thrombin Receptor Peptide, SFLLRN, on Aggregation and Release of 14C-Serotonin by Human Platelets Pretreated with Chymotrypsin or Serratia marcescens Protease \textbar Chymotrypsin cleaves glycoprotein Ib (GPIb) on platelets and reduces their responsiveness to thrombin; platelets from patients with the Bernard-Soulier syndrome, which lack GPIb, are also less responsive to thrombin than platelets from normal donors. However, Bernard-Soulier... \vphantom

publication date

  • 1995