Journal article
Comparative metabolism and distribution of rabbit heparin cofactor II and rabbit antithrombin in rabbits
Abstract
The metabolic characteristics of two rabbit plasma thrombin inhibitors, heparin cofactor II (HCII) and antithrombin (AT), have been compared in healthy young rabbits. Purified HCII and AT-alpha were differentially radiolabeled (125I, 131I) and injected intravenously; blood samples were taken at prescribed intervals over 7 days. From the plasma clearance curves of protein-bound radioactivities, fractional catabolic rates and compartmental …
Authors
Hatton MW; Hoogendoorn H; Southward SM; Ross B; Blajchman MA
Journal
American Journal of Physiology, Vol. 272, No. 5, pp. e824–e831
Publisher
American Physiological Society
Publication Date
May 1, 1997
DOI
10.1152/ajpendo.1997.272.5.e824
ISSN
0002-9513