Journal article
Anticoagulant Effects of Heparin in Neonatal Plasma'
Abstract
ABSTRACT: Available data on the anticoagulant effects of heparin in neonatal plasma are scarce and conflicting: relative to adult plasma, neonatal plasma has been reported to show both resistance as well as sensitivity to heparin. We explored this apparent paradox by comparing how well heparin accelerated inhibition of exogenous thrombin and prevented thrombin generation in defibrinated neonatal and adult plasmas. Using amidolytic assays, we …
Authors
Schmidt B; Ofosu FA; Mitchell L; Brooker LA; Andrew M
Journal
Pediatric Research, Vol. 25, No. 4, pp. 405–408
Publisher
Springer Nature
Publication Date
4 1989
DOI
10.1203/00006450-198904000-00020
ISSN
0031-3998