Journal article
Unexpected Effects of Aurin Tricarboxylic Acid on Human Platelets
Abstract
Aurin tricarboxylic acid (ATA) is a potent inhibitor of ristocetin-mediated platelet agglutination and of shear-induced, von Willebrand factor (vWf)-mediated platelet aggregation, probably via inhibition of vWf interaction with glycoprotein Ib (GPIb). We examined the effects of ATA (both the sodium salt and a solution of ATA in ethanol) on platelet functions in citrated plasma (PRP) and in suspensions of washed platelets in Tyrode-albumin …
Authors
Kinlough-Rathbone RL; Packham MA
Journal
Thrombosis and Haemostasis, Vol. 68, No. 02, pp. 189–193
Publisher
Thieme
Publication Date
1992
DOI
10.1055/s-0038-1656347
ISSN
0340-6245