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Comparative effects of heparin and LMW heparin on...
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Comparative effects of heparin and LMW heparin on hemostasis

Abstract

We performed studies to investigate the effect of protamine sulfate neutralization on both the anticoagulant and hemostatic effects of enoxaparin and heparin. Although the anti-Factor Xa effect of enoxaparin was incompletely neutralized by protamine sulfate in an experimental animal model, protamine sulfate reversed bleeding induced by hemorrhagic doses of enoxaparin.

Authors

Hirsh J; Buchanan MR

Volume

61

Pagination

pp. 11-17

Publisher

Elsevier

Publication Date

January 1991

DOI

10.1016/0049-3848(91)90399-h

Conference proceedings

Thrombosis Research

ISSN

0049-3848