Journal article
Antithrombotic Agents
Abstract
Recent advances in our understanding of the contribution of thrombin generation to arterial thrombosis and the role of platelets in venous thrombosis have prompted new treatment paradigms. Nonetheless, bleeding remains the major side effect of such treatments spurring the quest for new antithrombotic regimens with better benefit-risk profiles and for safer anticoagulants for existing and new indications. The aims of this article are to review …
Authors
Chan NC; Weitz JI
Journal
Circulation Research, Vol. 124, No. 3, pp. 426–436
Publisher
Wolters Kluwer
Publication Date
February 2019
DOI
10.1161/circresaha.118.313155
ISSN
0009-7330
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
Administration, OralAnticoagulantsAntithrombinsAspirinAtrial FibrillationClinical Trials as TopicCoronary DiseaseDrug Therapy, CombinationFactor XIFactor XIIFactor Xa InhibitorsHemorrhageHumansPeripheral Arterial DiseasePlaque, AtheroscleroticPlatelet AggregationPlatelet Aggregation InhibitorsPrimary PreventionRisk AssessmentRivaroxabanSecondary PreventionThrombinThrombosisVenous Thrombosis