Journal article
EFFECT OF SERA ON THROMBIN ACTIVATION RATE CONSTANTS: A ONE‐STAGE ASSAY OF THE EXTRINSIC SYSTEM
Abstract
A one-stage chromogenic assay sensitive to all factors of the extrinsic system has been developed. Diluted plasma is combined with tissue thromboplastin in the presence of S-2238, a thrombin-sensitive substrate. After a lag phase, log (A405/min) is linear with time up to the maximal thrombin concentration. The linear slope, b, is called the thrombin activation rate constant (TARC). Log b, or b, is linearly related to log transformations of …
Authors
Baughman DJ; Lytwyn A
Journal
Annals of the New York Academy of Sciences, Vol. 370, No. 1, pp. 822–835
Publisher
Wiley
Publication Date
6 1981
DOI
10.1111/j.1749-6632.1981.tb29788.x
ISSN
0077-8923