Journal article
Direct thrombin inhibitors in acute coronary syndromes: effect in patients undergoing early percutaneous coronary intervention
Abstract
AIMS: We evaluated the effect of direct thrombin inhibitors (DTIs) in patients undergoing early percutaneous coronary intervention (PCI), using the DTI Trialists' Collaboration database of 35,970 patients from 11 randomized trials of DTIs vs. heparin.
METHODS AND RESULTS: We performed a Cox proportional hazards regression analysis with PCI as a time-dependent covariate to assess the independent impact of DTIs according to the performance of …
Authors
Sinnaeve PR; Simes J; Yusuf S; Garg J; Mehta S; Eikelboom J; Bittl JA; Serruys P; Topol EJ; Granger CB
Journal
European Heart Journal, Vol. 26, No. 22, pp. 2396–2403
Publisher
Oxford University Press (OUP)
Publication Date
November 1, 2005
DOI
10.1093/eurheartj/ehi590
ISSN
0195-668X