Journal article
Platelet Interactions with the Endothelium and the Subendothelium: the Role of Thrombin and Prostacyclin
Abstract
The adherence of 51Cr-labeled platelets to rabbit aortae everted on probes rotated in platelet-red cell suspensions has been measured. Platelet adherence to the subendothelium exposed by passage of a balloon catheter before everting the aortae was inhibited by compounds that increase platelet cyclic AMP levels (PGE1, PGI2 or dipyridamole). These agents, however, did not abolish platelet adherence to the subendothelium. Aspirin treatment of the …
Authors
Cazenave J-P; Dejana E; Kinlough-Rathbone R; Packham MA; Mustard F
Journal
Pathophysiology of Haemostasis and Thrombosis, Vol. 8, No. 3-5, pp. 183–192
Publisher
Karger Publishers
Publication Date
1979
DOI
10.1159/000214310
ISSN
1424-8832