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The Effect of Thrombin on Platelet Accumulation on...
Journal article

The Effect of Thrombin on Platelet Accumulation on the Vessel Wall - Influence of Heparin and Aspirin

Abstract

Rabbit aortae were removed from exsanguinated rabbits, washed, everted on probes, treated with thrombin, washed to remove unbound thrombin and used to measure the accumulation of 51Cr-labeled platelets in vitro. Thrombin pretreatment of normal rabbit aortae did not cause platelet accumulation on the endothelium; platelets appeared to accumulate only at sites where the subendothelium had been exposed. The quantitative data obtained with …

Authors

Dejan E; Cazenave J-P; Hatton MWC; Richardson M; Groves HM; Kinlough-Rathbone RL; Packham MA; Mustard JF

Journal

Thrombosis and Haemostasis, Vol. 50, No. 02, pp. 567–571

Publisher

Thieme

Publication Date

1983

DOI

10.1055/s-0038-1665257

ISSN

0340-6245