Journal article
The Oral Thrombin Inhibitor Dabigatran: Strengths and Weaknesses
Abstract
Since the quest for a better replacement of warfarin started several decades ago and new compounds were brought forward to clinical trials, the concept of an ideal anticoagulant frequently became presented in lectures and articles. We have here reviewed strengths and weaknesses of the oral thrombin inhibitor dabigatran in terms of pharmacokinetics and clinical data. When strengths clearly exceed the weaknesses for any characteristic, the drug …
Authors
Schulman S; Majeed A
Journal
Seminars in Thrombosis and Hemostasis, Vol. 38, No. 01, pp. 07–15
Publisher
Thieme
Publication Date
2 2012
DOI
10.1055/s-0031-1300946
ISSN
0094-6176