Journal article
Plasma Anticoagulant Mechanisms of Heparin, Heparan Sulfate, and Dermatan Sulfatea
Abstract
The relationship between two anticoagulant actions of glycosaminoglycans (GAGs), namely the catalysis of thrombin inhibition (assessed by thrombin-antithrombin-III and thrombin-heparin-cofactor-II formation) and the inhibition of prothrombin activation, was explored by comparing the effects of heparin, heparan sulfate, and dermatan sulfate on the two reactions in plasma. Heparan sulfate and dermatan sulfate were also resulfated in vitro to …
Authors
OFOSU FA; BUCHANAN MR; ANVARI N; SMITH LM; BLAJCHMAN MA
Journal
Annals of the New York Academy of Sciences, Vol. 556, No. 1, pp. 123–131
Publisher
Wiley
Publication Date
June 1989
DOI
10.1111/j.1749-6632.1989.tb22496.x
ISSN
0077-8923