Protein Binding Concept

subject area of

• 'MacDope': a simulation of drug disposition in the human body: applications in clinical pharmacokinetics.  Academic Article
• 2 Mechanisms of action of low molecular weight heparins and heparinoids  Academic Article
• Staphylococcus aureus Fibronectin-Binding Protein Serves as a Substrate for Coagulation Factor XIIIa:  Evidence for Factor XIIIa-Catalyzed Covalent Cross-Linking to Fibronectin and Fibrin  Academic Article
• YAP enhances the pro‐proliferative transcriptional activity of mutant p53 proteins  Academic Article
• A 23bp Insertion in the Endothelial Protein C Receptor (EPCR) Gene Impairs EPCR Function  Academic Article
• A Control Switch for Prothrombinase  Academic Article
• A High Affinity Interaction of Plasminogen with Fibrin Is Not Essential for Efficient Activation by Tissue-type Plasminogen Activator  Academic Article
• A Highly Dynamic Loop of the Pseudomonas aeruginosa PA14 Type IV Pilin Is Essential for Pilus Assembly  Academic Article
• A Highly Specific DNA Aptamer for RNase H2 from Clostridium difficile  Academic Article
• A Key Regulator of the Glycolytic and Gluconeogenic Central Metabolic Pathways in Sinorhizobium meliloti  Academic Article
• A Method for Expression and Purification of Soluble, Active Hsp47, a Collagen-Specific Molecular Chaperone  Academic Article
• A Model for Agonism and Antagonism in an Ancient and Ubiquitous cAMP-binding Domain  Academic Article
• A New Function of Human HtrA2 as an Amyloid-β Oligomerization Inhibitor  Academic Article
• A Novel Non-canonical Forkhead-associated (FHA) Domain-binding Interface Mediates the Interaction between Rad53 and Dbf4 Proteins  Academic Article
• A Pulsed Tangential-Flow Ultrafiltration Technique for Studying Protein-Drug Binding  Academic Article
• A Review of Techniques to Measure Protein Sorption to Soft Contact Lenses  Academic Article
• A Role for the Cleaved Cytoplasmic Domain of E-cadherin in the Nucleus  Academic Article
• A Solid-Phase Assay for the Quantitation of Total Protein Eluted from Balafilcon, Lotrafilcon, and Etafilcon Contact Lenses  Academic Article
• A T-to-G Transversion at Nucleotide −567 Upstream of HBG2 in a GATA-1 Binding Motif Is Associated with Elevated Hemoglobin F  Academic Article
• A Transgenic Mouse Model to Study Glucose Transporter 4myc Regulation in Skeletal Muscle  Academic Article
• A critical role for the C-terminus of Nej1 protein in Lif1p association, DNA binding and non-homologous end-joining  Academic Article
• A direct role for serum albumin in the cellular uptake of long-chain fatty acids  Academic Article
• A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation  Academic Article
• A human XRCC4–XLF complex bridges DNA  Academic Article
• A molecular defect in two families with hemolytic poikilocytic anemia: reduction of high affinity membrane binding sites for ankyrin.  Academic Article
• A new variant of methylmalonic acidemia-defective coenzyme-apoenzyme binding in cultured fibroblasts  Academic Article
• A non-canonical base pair within the human immunodeficiency virus Rev-responsive element is involved in both Rev and small molecule recognition  Academic Article
• A novel antithrombotic coronary stent: lysine-poly(HEMA)-modified cobalt–chromium stent with fibrinolytic activity  Academic Article
• A point mutation in the neu1 promoter recruits an ectopic repressor, Nkx3.2 and results in a mouse model of sialidase deficiency  Academic Article
• A solution NMR toolset to probe the molecular mechanisms of amyloid inhibitors  Academic Article
• AMP-activated protein kinase: the current landscape for drug development  Academic Article
• ANNUAL AND DIURNAL CHANGES IN PLASMA ANDROGEN AND CORTISOL IN ADULT MALE SQUIRREL MONKEYS (Saimiri sciureus) STUDIED LONGITUDINALLY  Academic Article
• Abnormal hemostasis in a knock‐in mouse carrying a variant of factor IX with impaired binding to collagen type IV  Academic Article
• Actin Filaments Facilitate Insulin Activation of the Src and Collagen Homologous/Mitogen-activated Protein Kinase Pathway Leading to DNA Synthesis and c-fos Expression  Academic Article
• Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII  Academic Article
• Activation of protein C and thrombin activable fibrinolysis inhibitor on cultured human endothelial cells  Academic Article
• Active site residue identity regulates cleavage preference of LAGLIDADG homing endonucleases  Academic Article
• Activity and subcellular compartmentalization of peroxisome proliferator-activated receptor α are altered by the centrosome-associated protein CAP350  Academic Article
• Acyldepsipeptide Antibiotics Induce the Formation of a Structured Axial Channel in ClpP: A Model for the ClpX/ClpA-Bound State of ClpP  Academic Article
• Adenine Release Is Fast in MutY-catalyzed Hydrolysis of G:A and 8-Oxo-G:A DNA Mismatches  Academic Article
• Adenovirus E1A Directly Targets the E2F/DP-1 Complex  Academic Article
• Aggregatibacter actinomycetemcomitans Leukotoxin Utilizes a Cholesterol Recognition/Amino Acid Consensus Site for Membrane Association  Academic Article
• Akt Is Activated in Response to an Apoptotic Signal  Academic Article
• Alginate as an auxiliary bacterial membrane: binding of membrane-active peptides by polysaccharides*  Academic Article
• Allosteric Mechanisms of Nonadditive Substituent Contributions to Protein-Ligand Binding  Academic Article
• Allosteric linkers in cAMP signalling  Academic Article
• Alpha 2-macroglobulin and serum preferentially counteract the mitoinhibitory effect of transforming growth factor-beta 2 in rat hepatocytes.  Academic Article
• Altered sulfhydryl reactivity of hemoglobins and red blood cell membranes in congenital heinz body hemolytic anemia  Academic Article
• Amino Acid Substitutions in the Herpes Simplex Virus Transactivator VP16 Uncouple Direct Protein-Protein Interaction and DNA Binding from Complex Assembly and Transactivation  Academic Article
• Amphipathic helix and its relationship to the interaction of calcitonin with phospholipids  Academic Article
• An acquired factor V inhibitor associated with defective factor V function, storage and binding to multimerin 1  Academic Article
• An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein  Academic Article
• Analysis of the pi-pi stacking interactions between the aminoglycoside antibiotic kinase APH(3')-IIIa and its nucleotide ligands  Academic Article
• Anomalous thermal denaturing of proteins adsorbed to nanoparticles  Academic Article
• Anti-apoptotic function of the E2F transcription factor 4 (E2F4)/p130, a member of retinoblastoma gene family in cardiac myocytes  Academic Article
• Antibiotics for pneumonia therapy  Academic Article
• Antibodies to Indolealkylamines; Serotonin and Melatonin  Academic Article
• Antibodies to indolealkylamines II: site of conjugation of melatonin to protein using formaldehyde  Academic Article
• Antibody binding to megakaryocytesin vivoin patients with immune thrombocytopenia  Academic Article
• Antimicrobial activity of ceftriaxone versus cefotaxime: negative effect of serum albumin binding of ceftriaxone  Academic Article
• Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers  Academic Article
• Antithrombin III Sudbury: An Ala384 → pro mutation with abnormal thrombin-binding activity and thrombotic diathesis  Academic Article
• Antithrombin-III-Hamilton: a gene with a point mutation (guanine to adenine) in codon 382 causing impaired serine protease reactivity  Academic Article
• Anti–platelet factor 4 antibodies causing VITT do not cross-react with SARS-CoV-2 spike protein  Academic Article
• ApoA-I Mimetic Peptides with Differing Ability to Inhibit Atherosclerosis Also Exhibit Differences in Their Interactions with Membrane Bilayers  Academic Article
• Apoptotic Release of Histones from Nucleosomes  Academic Article
• Application of Combinatorial Libraries and Protein Engineering to the Discovery of Novel Anti-Thrombotic Drugs  Conference Paper
• Architecture of the type II secretion and type IV pilus machineries  Academic Article
• Arginine Methylation Regulates Telomere Length and Stability  Academic Article
• Aromatic Residue Position on the Nonpolar Face of Class A Amphipathic Helical Peptides Determines Biological Activity  Academic Article
• Aryl Hydrocarbon Receptor-Dependent Retention of Nuclear HuR Suppresses Cigarette Smoke-Induced Cyclooxygenase-2 Expression Independent of DNA-Binding  Academic Article
• Asialoglycoprotein clearance in the chicken: evidence for the lack of a hepatic asialoglycoprotein receptor  Academic Article
• Association of Neurofilament Proteins with Neuronal Cdk5 Activator  Academic Article
• Association of Phosphatidic Acid with the Bovine Mitochondrial ADP/ATP Carrier  Academic Article
• Association of the nucleocapsid protein N of vesicular stomatitis virus with phospholipids vesicles containing the matrix protein M  Academic Article
• Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine  Academic Article
• Autoregulation of the Drosophila disconnected Gene in the Developing Visual System  Academic Article
• Aβ Association Inhibition by Transferrin  Academic Article
• BL-7010 Demonstrates Specific Binding to Gliadin and Reduces Gluten-Associated Pathology in a Chronic Mouse Model of Gliadin Sensitivity  Academic Article
• Batroxobin Binds Fibrin with Higher Affinity and Promotes Clot Expansion to a Greater Extent than Thrombin  Academic Article
• Bax Forms an Oligomer via Separate, Yet Interdependent, Surfaces  Academic Article
• Bifunctional Catalysis by CDP-ribitol Synthase:  Convergent Recruitment of Reductase and Cytidylyltransferase Activities in Haemophilus influenzae and Staphylococcus aureus  Academic Article
• Binding Site Determinants for the LysR-Type Transcriptional Regulator PcaQ in the Legume Endosymbiont Sinorhizobium meliloti  Academic Article
• Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation  Academic Article
• Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53.  Academic Article
• Binding of heparin to plasma proteins and endothelial surfaces is inhibited by covalent linkage to antithrombin  Academic Article
• Biogenesis of ribosomes: Free ribosomal protein pools in Escherichia coli  Academic Article
• Biological and Clinical Implications of Lysozyme Deposition on Soft Contact Lenses  Academic Article
• Biologically active calcitonin analogs which have minimal interactions with phospholipids  Academic Article
• Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex  Academic Article
• BldD is a direct regulator of key developmental genes in Streptomyces coelicolor A3(2)  Academic Article
• Bringing order to a complex molecular machine: The assembly of the bacterial flagella  Academic Article
• Broad and Differential Animal Angiotensin-Converting Enzyme 2 Receptor Usage by SARS-CoV-2  Academic Article
• By Increasing the Affinity of Heparin for Fibrin, Zn²⁺ Promotes the Formation of a Ternary Heparin–Thrombin–Fibrin Complex That Protects Thrombin from Inhibition by Antithrombin  Academic Article
• CD,1H NMR and molecular modeling studies of the interaction of Ca2+ with substance P and Ala7-substance P in a non-polar solvent  Academic Article
• CSB interacts with BRCA1 in late S/G2 to promote MRN- and CtIP-mediated DNA end resection  Academic Article
• Ca2+-dependent Antifreeze Proteins  Academic Article
• Cadherin-11–mediated adhesion of macrophages to myofibroblasts establishes a profibrotic niche of active TGF-β  Academic Article
• Calcium and the Fc Receptor on Human Platelets  Academic Article
• Calcium binding and translocation properties of glucagon and its fragments  Academic Article
• Calorimetric study of peptide-phospholipid interactions: the glucagon-dimyristoylphosphatidylcholine complex  Academic Article
• Can extra protamine eliminate heparin rebound following cardiopulmonary bypass surgery?  Academic Article
• Carbapenems and Lipid Bilayers: Localization, Partitioning, and Energetics  Academic Article
• Cell of Origin in AML: Susceptibility to MN1-Induced Transformation Is Regulated by the MEIS1/AbdB-like HOX Protein Complex  Academic Article
• Cell-Free DNA Modulates Clot Structure and Impairs Fibrinolysis in Sepsis  Academic Article
• Cell-free protein synthesis and purification of human dopamine D2 receptor long isoform  Academic Article
• Cells differentiating into neuroectoderm undergo apoptosis in the absence of functional retinoblastoma family proteins.  Academic Article
• ChIP-on-Chip Analysis of In Vivo Mutant p53 Binding To Selected Gene Promoters  Academic Article
• Characteristics of Antibody Produced During Chronic Treatment with LHRH  Academic Article
• Characterization and Reconstitution of Drosophila γ-Tubulin Ring Complex Subunits  Academic Article
• Characterization of DalS, an ATP-binding Cassette Transporter for d-Alanine, and Its Role in Pathogenesis in Salmonella enterica  Academic Article
• Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis  Academic Article
• Characterization of platelet factor 4 amino acids that bind pathogenic antibodies in heparin‐induced thrombocytopenia  Academic Article
• Characterization of the 55-Residue Protein Encoded by the 9S E1A mRNA of Species C Adenovirus  Academic Article
• Characterization of the Interactions of Plasminogen and Tissue and Vampire Bat Plasminogen Activators with Fibrinogen, Fibrin, and the Complex of d-Dimer Noncovalently Linked to Fragment E  Academic Article
• Characterization of the PilN, PilO and PilP type IVa pilus subcomplex  Academic Article
• Characterization of the Putative Type III Secretion ATPase CdsN (Cpn0707) of Chlamydophila pneumoniae  Academic Article
• Characterization of the mouse lysosomal sialidase promoter  Academic Article
• Characterization of the spike protein of human coronavirus NL63 in receptor binding and pseudotype virus entry  Academic Article
• Che-1 modulates the decision between cell cycle arrest and apoptosis by its binding to p53  Academic Article
• Chemical and biosynthetic evolution of the antimycin-type depsipeptides  Academic Article
• Chkl binds and phosphorylates BAD protein.  Academic Article
• Chlamydia Outer Protein (Cop) B from Chlamydia pneumoniae possesses characteristic features of a type III secretion (T3S) translocator protein  Academic Article
• Cholesterol and the interaction of proteins with membrane domains  Academic Article
• Chromatography of heparin on Sepharose–lysine: molecular size fractionation and its relevance to thrombin and antithrombin III binding  Academic Article
• Circular dichroism studies on lipid-protein complexes of a hydrophobic myelin protein  Academic Article
• Cloning, genomic organization and expression pattern of a novel Drosophila gene, the disco-interacting protein 2 ( dip2 ), and its murine homolog  Academic Article
• Clot-bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III-independent inhibitors.  Academic Article
• Cofilin Nuclear-Cytoplasmic Shuttling Affects Cofilin-Actin Rod Formation During Stress  Academic Article
• Comparative analysis of 10 small molecules binding to carbonic anhydrase II by different investigators using Biacore technology  Academic Article
• Comparative effects of heparin and LMW heparin on hemostasis  Conference Paper
• Comparative genomic and functional analyses reveal a novel cis-acting PTEN regulatory element as a highly conserved functional E-box motif deleted in Cowden syndrome  Academic Article
• Comparison of Chemical Composition of Peritoneal Fluid and Serum  Academic Article
• Comparison of lowest energy conformations of dimethylcurine and methoxyverapamil: Evidence of ternary association of calcium channel, Ca2+, and calcium entry blockers  Academic Article
• Comparison of the Non-Specific Binding of Unfractionated Heparin and Low Molecular Weight Heparin (Enoxaparin) to Plasma Proteins  Academic Article
• Competitive Effects from an Artificial Tear Solution to Protein Adsorption  Academic Article
• Composite Active Site of an ABC ATPase  Academic Article
• Composition and Function of AP-1 Transcription Complexes during Muscle Cell Differentiation  Academic Article
• Computational Study of the Binding Modes of Caffeine to the Adenosine A_2A Receptor  Academic Article
• Conformational Analysis of the Ca²⁺-Bound Opioid Peptides: Implications for Ligand-Receptor Interaction  Academic Article
• Conformational Changes in Thrombin When Complexed by Serpins  Academic Article
• Conformational and biological properties of a covalently linked dimer of glucagon Reaction of mono- and bifunctional sulfenyl halides  Academic Article
• Conserved, unstructured regions in Pseudomonas aeruginosa PilO are important for type IVa pilus function  Academic Article
• Continuous spectrophotometric assay of a Sepharose-bound enzyme and its use to study kinetics of coupling of the enzyme to sepharose  Academic Article
• Contribution of Red Blood Cells to the Saturable Mechanism of Heparin Clearance  Academic Article
• Control of SERCA2a Ca2+ pump mRNA stability by nuclear proteins: role of domains in the 3′-untranslated region  Academic Article
• Control of sarcoplasmic/endoplasmic-reticulum Ca2+ pump expression in cardiac and smooth muscle  Academic Article
• Corn trypsin inhibitor coating attenuates the prothrombotic properties of catheters in vitro and in vivo  Academic Article
• Correlation between serotonin synthesis and 5-HT1A receptor binding in the living human brain: A combined α-[11C]MT and [18F]MPPF positron emission tomography study  Conference Paper
• Covalent Immune Recruiters: Tools to Gain Chemical Control Over Immune Recognition  Academic Article
• Covalent Stabilization of Antibody Recruitment Enhances Immune Recognition of Cancer Targets  Academic Article
• Covalent antithrombin-heparin effect on thrombin-thrombomodulin and activated protein C reaction with factor V/Va  Academic Article
• Covalently linking heparin to antithrombin enhances prothrombinase inhibition on activated platelets  Academic Article
• Cowden Syndrome–Affected Patients with PTEN Promoter Mutations Demonstrate Abnormal Protein Translation  Academic Article
• Cross-talk between Orphan Nuclear Hormone Receptor RZRα and Peroxisome Proliferator-activated Receptor α in Regulation of the Peroxisomal Hydratase-Dehydrogenase Gene  Academic Article
• Crp Is a Global Regulator of Antibiotic Production in Streptomyces  Academic Article
• Cryo-electron microscopy structure of the 30S subunit in complex with the YjeQ biogenesis factor  Academic Article
• Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery  Academic Article
• Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining  Academic Article
• Crystal Structure of StaL, a Glycopeptide Antibiotic Sulfotransferase from Streptomyces toyocaensis  Academic Article
• Crystal Structures of the Streptomyces coelicolor TetR-Like Protein ActR Alone and in Complex with Actinorhodin or the Actinorhodin Biosynthetic Precursor (S)-DNPA  Academic Article
• Crystallization and preliminary X-ray diffraction analysis of the human XRCC4–XLF complex  Academic Article
• Crystallographic analysis of Staphylococcus aureus LcpA, the primary wall teichoic acid ligase  Academic Article
• Ctp1 protein–DNA filaments promote DNA bridging and DNA double-strand break repair  Academic Article
• Cu(II)-Based Paramagnetic Probe to Study RNA–Protein Interactions by NMR  Academic Article
• DELPHI: accurate deep ensemble model for protein interaction sites prediction  Academic Article
• Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function  Academic Article
• Decoding the roles of pilotins and accessory proteins in secretin escort services  Academic Article
• Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions  Academic Article
• Delineation of key XRCC4/Ligase IV interfaces for targeted disruption of non-homologous end joining DNA repair  Academic Article
• Design of Novel Rho Kinase Inhibitors Using Energy Based Pharmacophore Modeling, Shape-Based Screening, in Silico Virtual Screening, and Biological Evaluation  Academic Article
• Deterioration of polyamino acid-coated alginate microcapsules in vivo  Academic Article
• Determination of albumin sorption to intraocular lenses by radiolabeling and confocal laser scanning microscopy  Academic Article
• Determination of the Functional Domain Organization of the Importin α Nuclear Import Factor  Academic Article
• Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors  Academic Article
• Differential Gene Expression in Thrombomodulin (TM; CD141)+ and TM− Dendritic Cell Subsets  Academic Article
• Dimerization and interactions of Brucella suis VirB8 with VirB4 and VirB10 are required for its biological activity  Academic Article
• Dipyridamole disposition after chronic administration: Effect of aspirin  Academic Article
• Direct Measurement of the Affinity between tBid and Bax in a Mitochondria-Like Membrane  Academic Article
• Direct interaction between SNAP-23 and L-type Ca²⁺channel  Academic Article
• Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS  Academic Article
• Displacement of Fibrin-bound Thrombin by r-Hirudin Precludes the Use of 131l-r-Hirudin for Detecting Pulmonary Emboli in the Rabbit  Academic Article
• Distance-Based Configurational Entropy of Proteins from Molecular Dynamics Simulations  Academic Article
• Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division  Academic Article
• Distinction between binding and endocytosis of human asialo-transferrin by the rat liver  Academic Article
• Dixdc1 Is a Critical Regulator of DISC1 and Embryonic Cortical Development  Academic Article
• Docking flexible ligands in proteins with a solvent exposure- and distance-dependent dielectric function  Academic Article
• Docking of calcium ions in proteins with flexible side chains and deformable backbones  Academic Article
• Domain-Specific Anti-IgE Antibodies Interfere with IgE Binding to FcεRII  Academic Article
• Domains in bacterial membranes and the action of antimicrobial agents  Academic Article
• Dropwort-induced metabolic reprogramming restrains YAP/TAZ/TEAD oncogenic axis in mesothelioma  Academic Article
• Drugs against superbugs: private lessons from bacteriophages  Academic Article
• Drugs targeting Bcl-2 family members as an emerging strategy in cancer  Academic Article
• Dual Function of Mitochondrial Nm23-H4 Protein in Phosphotransfer and Intermembrane Lipid Transfer  Academic Article
• Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains  Academic Article
• E-cadherin core fucosylation regulates nuclear β-catenin accumulation in lung cancer cells  Academic Article
• EFFECTS OF ACTIVE IMMUNIZATION OF FEMALE RABBITS AGAINST TESTOSTERONE  Academic Article
• EFFECTS OF DIFFERENT HEPATIC PATHOLOGIES ON DISPOSITION OF ALFENTANIL IN ANAESTHETIZED PATIENTS †  Academic Article
• EGF-grafted PDMS surfaces in artificial cornea applications  Academic Article
• Effect of Nonspecific Binding to Plasma Proteins on the Antithrombin Activities of Unfractionated Heparin, Low-Molecular-Weight Heparin, and Dermatan Sulfate  Academic Article
• Effect of phase transitions on the interaction of peptides and proteins with phospholipids  Academic Article
• Effects of metal binding affinity on the chemical and thermal stability of site-directed mutants of rat oncomodulin  Academic Article
• Encoding of a Homolog of the IFN-γ Receptor by Myxoma Virus  Academic Article
• Endocannabinoids and diacylglycerol kinase activity  Academic Article
• Endothelial NOS, estrogen receptor β, and HIFs cooperate in the activation of a prognostic transcriptional pattern in aggressive human prostate cancer  Academic Article
• Epitope specificity plays a critical role in regulating antibody-dependent cell-mediated cytotoxicity against influenza A virus  Academic Article
• Estimating Dopamine D2 Receptor Occupancy for Doses of 8 Antipsychotics  Academic Article
• Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents  Academic Article
• Evaluation of low PAI‐1 activity as a risk factor for hemorrhagic diathesis  Academic Article
• Evidence That Both Exosites on Thrombin Participate in Its High Affinity Interaction with Fibrin  Academic Article
• Evidence for Multiple Mechanisms for Membrane Binding and Integration via Carboxyl-Terminal Insertion Sequences  Academic Article
• Evidence for thrombin binding to dermatan sulphate sites in the rabbit aorta subendothelium in vitro  Academic Article
• Evidence of Kinetic Control of Ligand Binding and Staged Product Release in MurA (Enolpyruvyl UDP-GlcNAc Synthase)-Catalyzed Reactions,  Academic Article
• Evolution of a highly functional circular DNA aptamer in serum  Academic Article
• Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein  Academic Article
• Evolutionary and mechanistic insights into substrate and product accommodation of CTP:phosphocholine cytidylyltransferase fromPlasmodium falciparum  Academic Article
• Ex-Vivo and In-Vitro Evidence that Low Molecular Weight Heparins Exhibit Less Binding to Plasma Proteins than Unfractionated Heparin  Academic Article
• Exosite-interactive Regions in the A1 and A2 Domains of Factor VIII Facilitate Thrombin-catalyzed Cleavage of Heavy Chain  Academic Article
• Exosites 1 and 2 Are Essential for Protection of Fibrin-bound Thrombin from Heparin-catalyzed Inhibition by Antithrombin and Heparin Cofactor II  Academic Article
• Expression and purification of recombinant human receptor for advanced glycation endproducts in Escherichia coli  Academic Article
• Expression of nanomolar-affinity binding sites for melatonin in Syrian hamster RPMI 1846 melanoma cells  Academic Article
• Extending the lifetime of anticoagulant oligodeoxynucleotide aptamers in blood  Academic Article
• Extraction versus In Situ Techniques for Measuring Surface-Adsorbed Lysozyme  Academic Article
• Extremely Potent Block of Bacterial Voltage-Gated Sodium Channels by µ-Conotoxin PIIIA  Academic Article
• Factors that Influence In Vitro Cholesterol Deposition on Contact Lenses  Academic Article
• Fibrinogen surface distribution correlates to platelet adhesion pattern on fluorinated surface-modified polyetherurethane  Academic Article
• Fluorescence studies on a membrane-embedded peptide from the carboxy terminus of lipophilin  Academic Article
• Fluorinated surface-modifying macromolecules: Modulating adhesive protein and platelet interactions on a polyether-urethane  Academic Article
• Folded cavity SOI microring sensors for high sensitivity and real time measurement of biomolecular binding  Academic Article
• Formation of water-soluble complex between the 1-34 fragment of parathyroid hormone and dimyristoylphosphatidylcholine  Academic Article
• Fragmentation of Haptoglobin by Plasmin  Academic Article
• From p63 to p53 across p73  Academic Article
• FtsY Binds to the Escherichia coli Inner Membrane via Interactions with Phosphatidylethanolamine and Membrane Proteins  Academic Article
• Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo  Academic Article
• Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition  Academic Article
• Gain of function of mutant p53: The mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation  Academic Article
• Ganglioside embedded in reconstituted lipoprotein binds cholera toxin with elevated affinity  Academic Article
• Genetic Interaction Screens with Ordered Overexpression and Deletion Clone Sets Implicate the Escherichia coli GTPase YjeQ in Late Ribosome Biogenesis  Academic Article
• Genome Wide Association Identifies Common Variants at the SERPINA6/SERPINA1 Locus Influencing Plasma Cortisol and Corticosteroid Binding Globulin  Academic Article
• Getting Closer to P-Selectin  Academic Article
• Giardia lamblia RNA Polymerase II  Academic Article
• Glucose-Induced Thermal Stabilization of the Native Conformation of GLUT 1  Academic Article
• Glycogen synthase kinase-3 in insulin and Wnt signalling: a double-edged sword?  Academic Article
• HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase  Academic Article
• HIV-1 gp120 Induces TLR2- and TLR4-Mediated Innate Immune Activation in Human Female Genital Epithelium  Academic Article
• HUMAN TRANSFERRIN, ASIALOTRANSFERRIN AND THE INTERMEDIATE FORMS  Academic Article
• Haptoglobin testing in hemolysis: Measurement and interpretation  Academic Article
• Hemoglobin Binding by Enzymatic Fragments of Haptoglobin  Academic Article
• Heparin Binding to Plasma Proteins, an Important Mechanism for Heparin Resistance  Academic Article
• Heparin binding proteins. Contribution to heparin rebound after cardiopulmonary bypass.  Academic Article
• Heparin/Heparan Sulfate (HP/HS) Interacting Protein (HIP) Supports Cell Attachment and Selective, High Affinity Binding of HP/HS  Academic Article
• Heparin‐induced thrombocytopenia – therapeutic concentrations of danaparoid, unlike fondaparinux and direct thrombin inhibitors, inhibit formation of platelet factor 4–heparin complexes  Academic Article
• Herpes Simplex Virus 1 Tegument Protein US11 Downmodulates the RLR Signaling Pathway via Direct Interaction with RIG-I and MDA-5  Academic Article
• Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs  Academic Article
• High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry  Academic Article
• Histidine-rich Glycoprotein Binds Fibrin(ogen) with High Affinity and Competes with Thrombin for Binding to the γ′-Chain  Academic Article
• Histidine-rich glycoprotein binds DNA and RNA and attenuates their capacity to activate the intrinsic coagulation pathway  Academic Article
• Homology Models of μ-Opioid Receptor with Organic and Inorganic Cations at Conserved Aspartates in the Second and Third Transmembrane Domains  Academic Article
• Homology modeling and structure-based design improve hydrophobic interaction chromatography behavior of integrin binding antibodies  Academic Article
• Host Cell Factor-1 Interacts with and Antagonizes Transactivation by the Cell Cycle Regulatory Factor Miz-1  Academic Article
• Human Coronavirus OC43 Nucleocapsid Protein Binds MicroRNA 9 and Potentiates NF-κB Activation  Academic Article
• Human FVII(K62E) does not exhibit enhanced binding to tissue factor  Academic Article
• Human IgE binding and in vitro digestion of S-OVA  Academic Article
• Human Serum Albumin Inhibits Aβ Fibrillization through a “Monomer-Competitor” Mechanism  Academic Article
• Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins  Conference Paper
• Human platelets contain forms of factor V in disulfide-linkage with multimerin  Academic Article
• Hybrid sensor kinase PA1611 inPseudomonas aeruginosaregulates transitions between acute and chronic infection through direct interaction with RetS  Academic Article
• Hydrophobic Substitutions in the First Residue of the CRAC Segment of the gp41 Protein of HIV  Academic Article
• Hydrophobicity curvature and membrane fusion  Academic Article
• Hydroxypropyl Guar−Borate Interactions with Tear Film Mucin and Lysozyme  Academic Article
• HypF, a Carbamoyl Phosphate-converting Enzyme Involved in [NiFe] Hydrogenase Maturation  Academic Article
• Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase  Academic Article
• Identification and Structure Characterization of a Cdk Inhibitory Peptide Derived from Neuronal-specific Cdk5 Activator  Academic Article
• Identification and analysis of all components of a gel retardation assay by combination with immunoblotting.  Academic Article
• Identification and characterization of RED120: A conserved PWI domain protein with links to splicing and 3′-end formation  Academic Article
• Identification and characterization of a factor Va-binding site on human prothrombin fragment 2  Academic Article
• Identification of Caveolin-1 as a Fatty Acid Binding Protein  Academic Article
• Identification of Critical Residues on Thrombin Mediating Its Interaction with Fibrin  Academic Article
• Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2)  Academic Article
• Identification of a cluster of residues in transmembrane segment 6 of domain III of the cockroach sodium channel essential for the action of pyrethroid insecticides  Academic Article
• Identification of a conserved 8 aa insert in the PIP5K protein in theSaccharomycetaceaefamily of fungi and the molecular dynamics simulations and structural analysis to investigate its potential functional role  Academic Article
• Identification of a new catenin: the tyrosine kinase substrate p120cas associates with E-cadherin complexes.  Academic Article
• Identification of an XRCC1 DNA binding activity essential for retention at sites of DNA damage  Academic Article
• Identification of residues in the receptor-binding domain (RBD) of the spike protein of human coronavirus NL63 that are critical for the RBD–ACE2 receptor interaction  Academic Article
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• The Human Enhancer Blocker CTC-binding Factor Interacts with the Transcription Factor Kaiso  Academic Article
• The IgE-facilitated allergen binding (FAB) assay: Validation of a novel flow-cytometric based method for the detection of inhibitory antibody responses  Academic Article
• The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells  Academic Article
• The Novel Catenin p120casBinds Classical Cadherins and Induces an Unusual Morphological Phenotype in NIH3T3 Fibroblasts  Academic Article
• The Nucleotide-Binding Domain and Leucine-Rich Repeat Protein–3 Inflammasome Is Not Activated in Airway Smooth Muscle Upon Toll-Like Receptor–2 Ligation  Academic Article
• The Oxidative Stress Response in Caenorhabditis elegans Requires the GATA Transcription Factor ELT-3 and SKN-1/Nrf2  Academic Article
• The PEA3 Ets Transcription Factor Comprises Multiple Domains That Regulate Transactivation and DNA Binding  Academic Article
• The Peptidoglycan-Binding Protein FimV Promotes Assembly of the Pseudomonas aeruginosa Type IV Pilus Secretin  Academic Article
• The Platform Protein Is Essential for Type IV Pilus Biogenesis  Academic Article
• The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-β Oligomer Toxicity  Academic Article
• The Protein-Protein Interaction-Mediated Inactivation of PTEN  Academic Article
• The SseC translocon component in Salmonella enterica serovar Typhimurium is chaperoned by SscA  Academic Article
• The Structural Integrity of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII  Academic Article
• The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation  Academic Article
• The Winged Helix Domain of CSB Regulates RNAPII Occupancy at Promoter Proximal Pause Sites  Academic Article
• The affinity of human, rabbit and bovine thrombins for sepharose-lysine and other conjugates  Academic Article
• The amount of platelet-bound albumin parallels the amount of IgG on washed platelets from patients with immune thrombocytopenia  Academic Article
• The apparent preferential interaction of human plasma high density apolipoprotein A-I with gel-state phospholipids  Academic Article
• The appended tail region of heparin cofactor II and additional reactive centre loop mutations combine to increase the reactivity and specificity of α1-proteinase inhibitor M358R for thrombin  Academic Article
• The arrangement of cholesterol in membranes and binding of NAP-22  Academic Article
• The blood compatibility challenge. Part 2: Protein adsorption phenomena governing blood reactivity  Academic Article
• The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand  Academic Article
• The development and application of a serum assay for platelet-bindable IgG (S-PBIgG).  Academic Article
• The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs  Academic Article
• The effect of M&B 22948 on methacholine- and histamine-induced contraction and inositol 1,4,5-trisphosphate levels in guinea-pig tracheal tissue  Academic Article
• The effect of heparin on the affinity chromatography of plasminogen Demonstration of heparin-plasminogen interaction  Academic Article
• The effects of pulp mill effluent on the sex steroid binding protein in white sucker (Catostomus commersoni) and longnose sucker (C. catostomus)  Academic Article
• The effects of the trinitrophenylation of the amino groups of glucagon on its conformational properties and on its ability to activate rat liver adenylyl cyclase  Academic Article
• The fraction of recombinant factor VIII:Ag unable to bind von Willebrand factor has no FVIII coagulant activity: studiesin vitro  Academic Article
• The functions of the A1A2A3 domains in von Willebrand factor include multimerin 1 binding  Academic Article
• The hypersensitivity to thrombin of platelets from diabetic rats is not due to increased thrombin binding  Academic Article
• The inactivation of thrombin and plasmin by antithrombin III in the presence of Sepharose-heparin  Academic Article
• The inositol phosphatase MTMR4 is a novel target of the ubiquitin ligase Nedd4  Academic Article
• The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase  Academic Article
• The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor  Academic Article
• The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex  Academic Article
• The p120ctn-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides  Academic Article
• The platelet cytoskeleton stabilizes the interaction between αIIbβ3 and its ligand and induces selective movements of ligand-occupied integrin  Article
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults  Academic Article
• The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines  Academic Article
• The relevance of the structure of lysine bound to Sepharose for the affinity of rabbit plasminogen  Academic Article
• The role of molybdenum in the synthesis of Neurospora nitrate reductase  Academic Article
• The short heterodimer partner receptor differentially modulates peroxisome proliferator-activated receptor α-mediated transcription from the peroxisome proliferator-response elements of the genes encoding the peroxisomal β-oxidation enzymes acyl-CoA oxidase and hydratase-dehydrogenase  Academic Article
• The structure of the apocAMP‐binding domain ofHCN4 – a stepping stone toward understanding thecAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels  Academic Article
• The therapeutic potential of pharmacological chaperones and proteosomal inhibitors, Celastrol and MG132 in the treatment of sialidosis  Academic Article
• The transactivator proteins VP16 and GAL4 bind replication factor A  Academic Article
• The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin  Academic Article
• The variable anticoagulant response to unfractionated heparin in vivo reflects binding to plasma proteins rather than clearance  Academic Article
• Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase  Academic Article
• Thermodynamics of the binding of human apolipoprotein A-I to dimyristoylphosphatidylglycerol.  Academic Article
• Three types of human asialo-transferrin and their interactions with the rat liver  Academic Article
• Three-Dimensional Spatial Patterning of Proteins in Hydrogels  Academic Article
• Thrombin Activation of Factor XI on Activated Platelets Requires the Interaction of Factor XI and Platelet Glycoprotein Ibα with Thrombin Anion-binding Exosites I and II, Respectively  Academic Article
• Thrombin Inhibition by Hirudin: How Hirudin Inhibits Thrombin  Academic Article
• Thrombin Interacts with Thrombomodulin, Protein C, and Thrombin-activatable Fibrinolysis Inhibitor via Specific and Distinct Domains  Academic Article
• Thrombin binding to platelets from hypercholesterolaemic rats  Academic Article
• Thrombin structure and function  Academic Article
• Thrombospondin-1 inhibits VEGF levels in the ovary directly by binding and internalization via the low density lipoprotein receptor-related protein-1 (LRP-1)  Academic Article
• Tracking peptide–membrane interactions: Insights from in situ coupled confocal-atomic force microscopy imaging of NAP-22 peptide insertion and assembly  Academic Article
• Transcriptional regulation of ACC deaminase gene expression inPseudomonas putidaUW4  Academic Article
• Transcriptional regulation ofsdiAby cAMP-receptor protein, LeuO, and environmental signals inSalmonella entericaserovar Typhimurium  Academic Article
• Treatment of endothelium with the chemotherapy agent vincristine affects activated protein C generation to a greater degree in newborn plasma than in adult plasma  Academic Article
• Two Conserved Histidine Residues Are Critical to the Function of the TagF-like Family of Enzymes  Academic Article
• Type 1 Plasminogen Activator Inhibitor Binds to Fibrin via Vitronectin  Academic Article
• UTILITY OF IN VITRO TEST METHODS TO ASSESS THE ACTIVITY OF XENOESTROGENS IN FISH  Academic Article
• Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast  Academic Article
• Understanding the Molecular Basis for the Inhibition of the Alzheimer's Aβ-Peptide Oligomerization by Human Serum Albumin Using Saturation Transfer Difference and Off-Resonance Relaxation NMR Spectroscopy  Academic Article
• Unraveling Determinants of Affinity Enhancement in Dimeric Aptamers for a Dimeric Protein  Academic Article
• Upstream interactions of functional mammalian tRNA gene transcription complexes probed using a heterologous DNA-binding protein.  Academic Article
• Use of Allosteric Targets in the Discovery of Safer Drugs  Academic Article
• Using chemical exchange to assign non-covalent protein complexes in slow exchange with the free state: Enhanced resolution and efficient signal editing  Academic Article
• Variability in the human drug response  Academic Article
• Varicella-Zoster Virus Immediate-Early Protein ORF61 Abrogates the IRF3-Mediated Innate Immune Response through Degradation of Activated IRF3  Academic Article
• Vesicular stomatitis virus inhibits mitotic progression and triggers cell death  Academic Article
• Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface  Academic Article
• Volume properties of mixtures of lipophilin and dimyristoylphosphatidylcholine  Academic Article
• Water-in-Silicone Oil Emulsion Stabilizing Surfactants Formed From Native Albumin and α,ω-Triethoxysilylpropyl-Polydimethylsiloxane  Academic Article
• YAP1 Meets Tumor Suppression  Academic Article
• YjeQ, an Essential, Conserved, Uncharacterized Protein from Escherichia coli, Is an Unusual GTPase with Circularly Permuted G-Motifs and Marked Burst Kinetics  Academic Article
• Zinc delays clot lysis by attenuating plasminogen activation and plasmin-mediated fibrin degradation  Academic Article
• Zn2+ Mediates High Affinity Binding of Heparin to the αC Domain of Fibrinogen  Academic Article
• [33] Immobilized subunits  Academic Article
• c-Jun Homodimers Can Function as a Context-Specific Coactivator  Academic Article
• cAMP-dependent allostery and dynamics in Epac: an NMR view  Academic Article
• iso-Lactam and reduced amide analogues of the peptidomimetic dopamine receptor modulator 3(R)-[(2(S)-Pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide  Academic Article
• p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor  Academic Article
• p73-Mediated Chemosensitivity: A Preferential Target of Oncogenic Mutant p53  Academic Article
• tBid Undergoes Multiple Conformational Changes at the Membrane Required for Bax Activation  Academic Article
• β-Catenin/Smad3 Interaction Regulates Transforming Growth Factor-β-Induced Epithelial to Mesenchymal Transition in the Lens  Academic Article
• β-Subunit of the voltage-gated Ca ²⁺ channel Cav1.2 drives signaling to the nucleus via H-Ras  Academic Article