Journal article
Studies of the Metabolism of Asialotransferrins: The Mechanism for the Hypercatabolism of Human Asialotransferrin in the Rabbit
Abstract
The behavior in vivo of human asialotransferrin in rabbits was studied in such a manner as to permit a comparison of this catabolic process with the generalized hepatic clearance mechanism for asialoglycoproteins described by Ashwell and Morell.Progressive desialylation of human transferrin in the range 50–100% yielded transferrin molecules with circulation times inversely proportional to the loss of sialic acid. The shape of plasma …
Authors
Regoeczi E; Hatton MW
Journal
Biochemistry and Cell Biology, Vol. 52, No. 7, pp. 645–651
Publisher
Canadian Science Publishing
Publication Date
July 1, 1974
DOI
10.1139/o74-092
ISSN
0829-8211