YAP1 Meets Tumor Suppression Journal Articles

abstract

• In this issue of Molecular Cell, Matallanas et al. (2007) demonstrate that RASSF1A-induced apoptosis impinges on the transcriptional coactivator YAP1, whose nuclear translocation and binding to p73 result in proper execution of the cell death pathway. Indeed, RASSF1A silencing in tumors inhibits YAP1-p73-dependent apoptosis.

authors

• Strano, Sabrina
• Blandino, Giovanni

status

• published 

publication date

• September 2007

has subject area

• 06 Biological Sciences (FoR)
• 11 Medical and Health Sciences (FoR)
• Adaptor Proteins, Signal Transducing (MeSH)
• Apoptosis (MeSH)
• DNA-Binding Proteins (MeSH)
• Developmental Biology (Science Metrix)
• Humans (MeSH)
• Nuclear Proteins (MeSH)
• Phosphoproteins (MeSH)
• Protein Binding (MeSH)
• Protein Serine-Threonine Kinases (MeSH)
• Proto-Oncogene Proteins c-raf (MeSH)
• Serine-Threonine Kinase 3 (MeSH)
• Transcription Factors (MeSH)
• Transcription, Genetic (MeSH)
• Tumor Protein p73 (MeSH)
• Tumor Suppressor Protein p53 (MeSH)
• Tumor Suppressor Proteins (MeSH)
• YAP-Signaling Proteins (MeSH)

published in

• Molecular Cell  Journal

keywords

• Adaptor Proteins, Signal Transducing
• Apoptosis
• DNA-Binding Proteins
• Humans
• Nuclear Proteins
• Phosphoproteins
• Protein Binding
• Protein Serine-Threonine Kinases
• Proto-Oncogene Proteins c-raf
• Serine-Threonine Kinase 3
• Transcription Factors
• Transcription, Genetic
• Tumor Protein p73
• Tumor Suppressor Protein p53
• Tumor Suppressor Proteins
• YAP-Signaling Proteins

Digital Object Identifier (DOI)

• 10.1016/j.molcel.2007.09.004

PubMed ID

• 17889659

start page

• 863

end page

• 864

volume

• 27

issue

• 6