Journal article
Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2
Abstract
The transforming potential of DNA tumor viruses derives mainly from the ability of their encoded oncogene products to interact with cellular proteins. Many of these viral oncoproteins share regions of sequence similarity, designated conserved region 1 and 2, which have been implicated in complex formation with pRb, the product of the retinoblastoma tumor suppressor gene, and related p107 and p130 species. It has now been shown that the EIA …
Authors
Desjardins P; Pilon A; Hassell JA; Mes-Masson A-M
Journal
Virus Research, Vol. 47, No. 1, pp. 85–90
Publisher
Elsevier
Publication Date
1 1997
DOI
10.1016/s0168-1702(96)01404-9
ISSN
0168-1702