Binding Sites
Concept
Vocabulary Service
Overview
subject area of
-
2-[<sup>125</sup>I]Iodomelatonin Binding in the Brains of Four Salmonids Academic Article
-
2-[<sup>125</sup>l]lodomelatonin Binding Sites in the Lung and Heart: A Link between the Photoperiodic Signal, Melatonin, and the Cardiopulmonary System Academic Article
-
2-[125I]Iodomelatonin binding sites in the quail heart: Characteristics, distribution and modulation by guanine nucleotides and cations Academic Article
-
2-[125I]iodomelatonin-binding sites in the human kidney and the effect of guanosine 5'-O-(3-thiotriphosphate). Academic Article
-
3 minutes to precisely measure morphogen concentration Academic Article
-
3-[(3-Cholamidopropyl)dimethylammonio]-1-Propane Sulfonate-Solubilized Binding Sites for 2-[125I]Iodomelatonin in Chick Brain Retain Sensitivity to Guanine Nucleotides Academic Article
-
5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II Academic Article
-
Molecular characterization of the Pseudomonas aeruginosa
serotype O5 (PAO1) B-band lipopolysaccharide gene cluster Academic Article
-
Campylobacter jejuni KDO8P Synthase, Its Inhibition by KDO8P Oxime, and Control of the Residence Time of Slow-Binding Inhibition Academic Article
-
In vivo and in vitro Validation of Reference Tissue Models for the mGluR5 Ligand [11C]ABP688 Academic Article
-
A 2.13 Å Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region Academic Article
-
A Complex between the Catalytic and Regulatory Subunits of Aspartate Transcarbamylase Academic Article
-
A Deoxyribozyme with a Novel Guanine Quartet-Helix Pseudoknot Structure Academic Article
-
A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP Academic Article
-
A New Target for Antibiotic Development Academic Article
-
A Novel Double-stranded RNA-binding Protein, Disco Interacting Protein 1 (DIP1), Contributes to Cell Fate Decisions during Drosophila Development Academic Article
-
A Small Molecule Discrimination Map of the Antibiotic Resistance Kinome Academic Article
-
A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection Academic Article
-
A human XRCC4–XLF complex bridges DNA Academic Article
-
A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin Academic Article
-
A molecular defect in two families with hemolytic poikilocytic anemia: reduction of high affinity membrane binding sites for ankyrin. Academic Article
-
A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation Academic Article
-
A neurochemical basis for the antipsychotic activity of loxapine: interactions with dopamine D1, D2, D4 and serotonin 5-HT2 receptor subtypes. Academic Article
-
A novel Myb-related protein involved in transcriptional activation of encystation genes in Giardia lamblia Academic Article
-
A p56 Ligand Serves as a Coactivator of an Orphan Nuclear Hormone Receptor Academic Article
-
A peptide derived from a tissue factor loop region functions as a tissue factor-factor VIIa antagonist Academic Article
-
A role for the ETS domain transcription factor PEA3 in myogenic differentiation Academic Article
-
AMP inhibition of reactions of ADP with washed platelets from humans and rabbits Article
-
AMP-Activated Protein Kinase-Regulated Activation of the PGC-1α Promoter in Skeletal Muscle Cells Academic Article
-
AMP-activated protein kinase: the current landscape for drug development Academic Article
-
Abnormal hemostasis in a knock‐in mouse carrying a variant of factor IX with impaired binding to collagen type IV Academic Article
-
Access and Binding of Local Anesthetics in the Closed Sodium Channel Academic Article
-
Acetyltransfer Precedes Uridylyltransfer in the Formation of UDP-N-acetylglucosamine in Separable Active Sites of the Bifunctional GlmU Protein of Escherichia coli Academic Article
-
Acidic pH changes receptor binding specificity of Helicobacter pylori: a binary adhesion model in which surface heat shock (stress) proteins mediate sulfatide recognition in gastric colonization Academic Article
-
Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII Academic Article
-
Activation of a recombinant human factor VII structural analogue alters its affinity of binding to tissue factor Academic Article
-
Activation of theWT1tumor suppressor gene promoter by Pea3 Academic Article
-
Active Site Interference and Asymmetric Activation in the Chemotaxis Protein Histidine Kinase CheA Academic Article
-
Active Subunits of Transaldolase Bound to Sepharose Academic Article
-
Active site labeling of the gentamicin resistance enzyme AAC(6')-APH(2") by the lipid kinase inhibitor wortmannin Academic Article
-
Active-Site Labeling of an Aminoglycoside Antibiotic Phosphotransferase (APH(3')-IIIa) Academic Article
-
Adsorption of Fibrinogen and Lysozyme on Silicon Grafted with Poly(2-methacryloyloxyethyl Phosphorylcholine) via Surface-Initiated Atom Transfer Radical Polymerization Academic Article
-
Affinity chromatography of a regulatory enzyme based on specific interaction with the effector Academic Article
-
Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids Academic Article
-
AlgK Is a TPR-Containing Protein and the Periplasmic Component of a Novel Exopolysaccharide Secretin Academic Article
-
Alignment/Phylogeny of the Papain Superfamily of Cysteine Proteases Academic Article
-
Alpha-2 adrenoceptors on nerves and muscles of rat uterus. Academic Article
-
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis Academic Article
-
An Extensive Interaction Interface between Thrombin and Factor V Is Required for Factor V Activation Academic Article
-
An alternative pathway for expression of p56lck from type I promoter transcripts in colon carcinoma Academic Article
-
Androgen Receptors in Prostatic Tissue: Evaluation of Systematic Errors and Comparison of Three Procedures to Correct for Nonspecific Binding Sites in the Binding Assays Academic Article
-
Antibiotic stops ‘ping-pong’ match Academic Article
-
Antibodies to Indolealkylamines; Serotonin and Melatonin Academic Article
-
Antithrombin-III-Hamilton: a gene with a point mutation (guanine to adenine) in codon 382 causing impaired serine protease reactivity Academic Article
-
Application of Combinatorial Libraries and Protein Engineering to the Discovery of Novel Anti-Thrombotic Drugs Conference Paper
-
Architecture and Pore Block of Eukaryotic Voltage-Gated Sodium Channels in View of NavAb Bacterial Sodium Channel Structure Academic Article
-
Architecture of the Neuronal Nicotinic Acetylcholine Receptor Ion Channel at the Binding Site of bis-Ammonium Blockers Academic Article
-
Association Analysis Indicates That a Variant GATA-Binding Site in the PIK3CB Promoter Is a Cis-Acting Expression Quantitative Trait Locus for This Gene and Attenuates Insulin Resistance in Obese Children Academic Article
-
Asthma caused by occupational exposure to a furan-based binder system Academic Article
-
Asymmetric distribution of sites with high affinity for antithrombin III in rat skin heparin proteoglycans. Academic Article
-
Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine Academic Article
-
Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine Academic Article
-
Autoradiographic Localization of Human Calcitonin Sensitive Binding Sites in Rat Brain. Academic Article
-
BCL11A represses HBG transcription in K562 cells Academic Article
-
Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA Academic Article
-
Batrachotoxin, Pyrethroids, and BTG 502 Share Overlapping Binding Sites on Insect Sodium Channels Academic Article
-
Batroxobin Binds Fibrin with Higher Affinity and Promotes Clot Expansion to a Greater Extent than Thrombin Academic Article
-
Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax Academic Article
-
Benzodiazepine-induced inhibition of human malignant melanoma (M-6) cell growth. Academic Article
-
Beta adrenoreceptor in vascular smooth muscle with special reference to subcellular localization and number of binding sites. Academic Article
-
Bifunctional Catalysis by CDP-ribitol Synthase: Convergent Recruitment of Reductase and Cytidylyltransferase Activities in Haemophilus influenzae and Staphylococcus aureus Academic Article
-
Binding Site Determinants for the LysR-Type Transcriptional Regulator PcaQ in the Legume Endosymbiont
Sinorhizobium meliloti Academic Article
-
Binding of Aggregated Immunoglobulins to the Human Platelet Fc Receptors: A Mechanism of Platelet to Platelet Bridging Academic Article
-
Binding of Heparin to Metals Academic Article
-
Binding of NAP-22, a Calmodulin-Binding Neuronal Protein, to Raft-like Domains in Model Membranes Academic Article
-
Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation Academic Article
-
Binding of a glucagon photoaffinity label to rat liver plasma membranes and its effect on adenylate cyclase activity before and after photolysis Academic Article
-
Binding of progesterone to cell surfaces of human granulosa-lutein cells Academic Article
-
Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex Academic Article
-
Bivalent direct thrombin inhibitors: hirudin and bivalirudin Academic Article
-
Borate Binding to Polyol-Stabilized Latex Academic Article
-
Breast cancer prognostic significance of a single nucleotide polymorphism in the proximal androgen response element of the prostate specific antigen gene promoter Academic Article
-
C/EBPβ (NF-M) Is Essential for Activation of the p20K Lipocalin Gene in Growth-Arrested Chicken Embryo Fibroblasts Academic Article
-
CD23-Mediated IgE Transport Across Human Intestinal Epithelium: Inhibition by Blocking Sites of Translation or Binding Academic Article
-
CD36 peptides enhance or inhibit CD36-thrombospondin binding. A two-step process of ligand-receptor interaction. Academic Article
-
CNS Dopamine Receptors: Effect of Prolyl-Leucyl-Glycinamide and Solubilization Academic Article
-
Ca2+ and Zn2+ binding properties of peptide substrates of vertebrate collagenase, MMP-1 Academic Article
-
Ca2+-dependent Antifreeze Proteins Academic Article
-
Calcium binding and translocation properties of glucagon and its fragments Academic Article
-
Calcium-channel antagonist binding to isolated vascular smooth muscle membranes Academic Article
-
Calreticulin modulates the in vitro DNA binding but not the in vivo transcriptional activation by peroxisome proliferator-activated receptor/retinoid X receptor heterodimers Academic Article
-
Capillary-Scale Frontal Affinity Chromatography/MALDI Tandem Mass Spectrometry Using Protein-Doped Monolithic Silica Columns Academic Article
-
Carbamoylphosphate requirement for synthesis of the active center of [NiFe]-hydrogenases Academic Article
-
Carbohydrate-binding Modules Recognize Fine Substructures of Cellulose Academic Article
-
ChIP-on-Chip Analysis of In Vivo Mutant p53 Binding To Selected Gene Promoters Academic Article
-
Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73 Academic Article
-
Characterization of protein-DNA interactions within the peroxisome proliferator-responsive element of the rat hydratase-dehydrogenase gene Academic Article
-
Characterization of specific GTP binding sites in C2C12 mouse skeletal muscle cells. Academic Article
-
Characterization of the calcium-binding site that regulates association of protein kinase C with phospholipid bilayers. Academic Article
-
Characterization of the mouse lysosomal sialidase promoter Academic Article
-
Characterization of the pancreatic hormones from the Brockmann body of the tilapia: implications for islet xenograft studies Academic Article
-
Chemical modification reveals involvement of tyrosine in ligand binding to dopamine D1 and D2 receptors. Academic Article
-
Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling. Academic Article
-
Chlamydia Outer Protein (Cop) B from Chlamydia pneumoniae possesses characteristic features of a type III secretion (T3S) translocator protein Academic Article
-
Chlamydia pneumoniae CopD Translocator Protein Plays a Critical Role in Type III Secretion (T3S) and Infection Academic Article
-
Chloride Channels of Glycine and GABA Receptors with Blockers: Monte Carlo Minimization and Structure-Activity Relationships Academic Article
-
Cholesterol Binding Does Not Predict Activity of the Steroidogenic Acute Regulatory Protein, StAR Academic Article
-
Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions with a Potassium Ion in the Selectivity Filter Academic Article
-
Cleavage-dependent Ligation by the FLP Recombinase Academic Article
-
Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line Academic Article
-
Cognitive impairments of alcoholic cirrhotic patients: correlation with endogenous benzodiazepine receptor ligands and increased affinity of platelet receptors. Academic Article
-
Cold-Active Winter Rye Glucanases with Ice-Binding Capacity Academic Article
-
Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations Academic Article
-
Comparison of the Effects of Heparin and Hirudin on Thrombin Binding to the Normal and the De-Endothelialized Rabbit Aorta In Vitro Academic Article
-
Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen. Academic Article
-
Complex formation of platelet thrombospondin with histidine-rich glycoprotein. Academic Article
-
Complex formation of platelet thrombospondin with plasminogen. Modulation of activation by tissue activator. Academic Article
-
Composite Active Site of an ABC ATPase Academic Article
-
Computational Analysis of the Crystal and Cryo-EM Structures of P-Loop Channels with Drugs Academic Article
-
Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels Chapter
-
Conformational Analysis of Free and Ca2+-bound forms of Verapamil and Methoxyverapamil Academic Article
-
Conformational Studies on Calcium Binding BytBoc-Leu-Pro-Tyr-Ala-NHCH3, a Tyrosine Kinase Substrate, in a Nonpolar Solvent Academic Article
-
Conformational analysis of d-tubocurarine: Implications for minimal dimensions of its binding site within ion channels Academic Article
-
Conformational and biological properties of a covalently linked dimer of glucagon Reaction of mono- and bifunctional sulfenyl halides Academic Article
-
Conformational studies on analogs of recombinant parathyroid hormone and Academic Article
-
Conserved Features and Evolutionary Shifts of the EDA Signaling Pathway Involved in Vertebrate Skin Appendage Development Academic Article
-
Construction of a recombinant adenovirus for efficient delivery of the I-Scel yeast endonuclease to human cells and its application in the in vivo cleavage of chromosomes to expose new potential telomeres Academic Article
-
Control of sarcoplasmic/endoplasmic-reticulum Ca2+ pump expression in cardiac and smooth muscle Academic Article
-
Cooperativity of papain-substrate interaction energies in the S2 to S2' subsites Academic Article
-
Cowden Syndrome–Affected Patients with PTEN Promoter Mutations Demonstrate Abnormal Protein Translation Academic Article
-
Cross-chimeric analysis of selectivity of secretin and VPAC(1) receptor activation. Academic Article
-
Crp Is a Global Regulator of Antibiotic Production in
Streptomyces Academic Article
-
Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery Academic Article
-
Crystal Structure of Homoserine Transacetylase from Haemophilus influenzae Reveals a New Family of α/β-Hydrolases, Academic Article
-
Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining Academic Article
-
Crystal structure of the DdrB/ssDNA complex from Deinococcus radiodurans reveals a DNA binding surface involving higher-order oligomeric states Academic Article
-
Crystal structure of the Xrcc4 DNA repair protein and implications for end joining Academic Article
-
Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases Academic Article
-
Crystallization of the DdrB–DNA complex fromDeinococcus radiodurans Academic Article
-
Crystals of modified bovine neurophysin II Academic Article
-
Cytokine-Induced Hepatic Apoptosis Is Dependent on FGL2/Fibroleukin: The Role of Sp1/Sp3 and STAT1/PU.1 Composite cis Elements Academic Article
-
DELPHI: accurate deep ensemble model for protein interaction sites prediction Academic Article
-
DNA Mismatch Repair: From Structure to Mechanism Academic Article
-
Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function Academic Article
-
Defining the heparin-binding domain of antithrombin Academic Article
-
Defining the sequence specificity of theSaccharomyces cerevisiae DNA binding protein REB1p by selecting binding sites from random-sequence oligonucleotides Academic Article
-
Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIα Academic Article
-
Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions Academic Article
-
Design and Synthesis of Photoaffinity-Labeling Ligands of the l-Prolyl-l-leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor Academic Article
-
Design of Novel Rho Kinase Inhibitors Using Energy Based Pharmacophore Modeling, Shape-Based Screening, in Silico Virtual Screening, and Biological Evaluation Academic Article
-
Design of a protein-targeted DNA aptamer using atomistic simulation Academic Article
-
Detection and Characterization of a Phospholactoyl-Enzyme Adduct in the Reaction Catalyzed by UDP-N-acetylglucosamine Enolpyruvoyl Transferase, MurZ Academic Article
-
Determinants for calcitonin analog interaction with the calcitonin receptor N-terminus and transmembrane-loop regions. Academic Article
-
Determination of Strong Ligand Sites in Sewage Effluent-Impacted Waters by Competitive Ligand Titration with Silver Academic Article
-
Determination of the molecular states of the processive endocellulase Thermobifida fusca Cel9A during crystalline cellulose depolymerization Academic Article
-
Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT Academic Article
-
Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors Academic Article
-
Differential Effects of Short Photoperiod on 2-[<sup>125</sup>l]lodomelatonin Binding in the Testis and Brain of Quail Academic Article
-
Dimensions of the ion channel in neuronal nicotinic acetylcholine receptor as estimated from analysis of conformation-activity relationships of open-channel blocking drugs Academic Article
-
Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa Academic Article
-
Dissociation of Thrombin's Substrate Interactions Using Site-Directed Mutagenesis Academic Article
-
Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division Academic Article
-
Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography Academic Article
-
Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression. Academic Article
-
Docking flexible ligands in proteins with a solvent exposure- and distance-dependent dielectric function Academic Article
-
Docking of calcium ions in proteins with flexible side chains and deformable backbones Academic Article
-
Domain Mapping of Heat Shock Protein 70 Reveals That Glutamic Acid 446 and Arginine 447 Are Critical for Regulating Superoxide Dismutase 2 Function Academic Article
-
Drugs acting at the glycine site on the NMDA receptor as cognitive enhancers in patients with Alzheimer's disease Academic Article
-
Dynamics of interacting edge defects in copolymer lamellae Academic Article
-
Dynamin Interacts with Members of the Sumoylation Machinery Academic Article
-
ETS Proteins and MMPs: Partners in Invasion and Metastasis Academic Article
-
Effects of Cu Ions and Explicit Water Molecules on the Copper Binding Domain of Amyloid Precursor Protein APP(131–189): A Molecular Dynamics Study Academic Article
-
Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide Academic Article
-
Electron spin resonance spectroscopy reveals alpha-phenyl-N-tert-butylnitrone spin-traps free radicals in rat striatum and prevents haloperidol-induced vacuous chewing movements in the rat model of human tardive dyskinesia Academic Article
-
Eliminating Competition: Characterizing and Eliminating Competitive Binding at Separate Sites between DAHP Synthase’s Essential Metal Ion and the Inhibitor DAHP Oxime Academic Article
-
Elucidation of pyrethroid and DDT receptor sites in the voltage-gated sodium channel Academic Article
-
Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors Academic Article
-
Enhanced binding of fibrinogen by the subendothelium after treatment of the rabbit aorta with thrombin. Academic Article
-
Enolpyruvyl Activation by Enolpyruvylshikimate-3-phosphate Synthase Academic Article
-
Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase Academic Article
-
Establishing the Principles of Recognition in the Adenine-Binding Region of an Aminoglycoside Antibiotic Kinase [APH(3‘)-IIIa] Academic Article
-
Estrogen and progesterone binding sites in renal cell carcinoma Academic Article
-
Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents Academic Article
-
Evaluation of the Calmodulin-SOX9 Interaction by “Magnetic Fishing” Coupled to Mass Spectrometry Academic Article
-
Evidence That Both Exosites on Thrombin Participate in Its High Affinity Interaction with Fibrin Academic Article
-
Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin Academic Article
-
Evidence for Calcitonin Receptor Heterogeneity: Binding Studies with Nonhelical Analogs* Academic Article
-
Evidence for Dual Binding Sites for 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) in Insect Sodium Channels Academic Article
-
Evidence for Multiple Mechanisms for Membrane Binding and Integration via Carboxyl-Terminal Insertion Sequences Academic Article
-
Evidence for thrombin binding to dermatan sulphate sites in the rabbit aorta subendothelium in vitro Academic Article
-
Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein Academic Article
-
Expression of nanomolar-affinity binding sites for melatonin in Syrian hamster RPMI 1846 melanoma cells Academic Article
-
Extension of the Single Amino Acid Chelate Concept (SAAC) to Bifunctional Biotin Analogues for Complexation of the M(CO)3+1 Core (M = Tc and Re): Syntheses, Characterization, Biotinidase Stability, and Avidin Binding Academic Article
-
Extracellular guanosine 5′ triphosphate enhances nerve growth factor-induced neurite outgrowth via increases in intracellular calcium Academic Article
-
Factor XIIIa Mediated Attachment of S. aureus Fibronectin-Binding Protein A (FnbA) to Fibrin: Identification of Gln103 as a Major Cross-Linking Site Academic Article
-
Folded cavity SOI microring sensors for high sensitivity and real time measurement of biomolecular binding Academic Article
-
Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4 Academic Article
-
Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae Academic Article
-
Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo Academic Article
-
GTP modulates [125I]iodomelatonin binding to a picomolar-affinity site in the Syrian hamster hypothalamus Academic Article
-
Gauging a Hydrocarbon Ruler by an Intrinsic Exciton Probe Academic Article
-
General occurrence of binding synergism in zinc proteases and its possible significance Academic Article
-
Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria Academic Article
-
Giardia lamblia RNA Polymerase II Academic Article
-
Glycosaminoglycans Bind Factor Xa in a Ca2+-Dependent Fashion and Modulate Its Catalytic Activity Academic Article
-
HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase Academic Article
-
HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions Academic Article
-
HSP47: a potential target for fibrotic diseases and implications for therapy Academic Article
-
Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus Academic Article
-
Hemoglobin Binding by Enzymatic Fragments of Haptoglobin Academic Article
-
Heparin binds to human monocytes and modulates their procoagulant activities and secretory phenotypes. Effects of histidine-rich glycoprotein Academic Article
-
Heparin enhances active site-dependent binding of tissue-type plasminogen activator to endothelial cells Academic Article
-
Heparin/Heparan Sulfate (HP/HS) Interacting Protein (HIP) Supports Cell Attachment and Selective, High Affinity Binding of HP/HS Academic Article
-
High Temperature Stabilization of DNA in Complexes with Cationic Lipids Academic Article
-
High affinity Ca-binding to smooth muscle plasma membrane: Inhibition by cations Academic Article
-
High frequency recombination betweenloxP sites in human chromosomes mediated by an adenovirus vector expressing Cre recombinase Academic Article
-
High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13 Academic Article
-
High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry Academic Article
-
Histidine-rich Glycoprotein Binds Fibrin(ogen) with High Affinity and Competes with Thrombin for Binding to the γ′-Chain Academic Article
-
Homology Model of Dihydropyridine Receptor: Implications for L-type Ca2+ Channel Modulation by Agonists and Antagonists Academic Article
-
Homology Models of μ-Opioid Receptor with Organic and Inorganic Cations at Conserved Aspartates in the Second and Third Transmembrane Domains Academic Article
-
Homology Requirements for Ligation and Strand Exchange by the FLP Recombinase Academic Article
-
Host Cell Factor-1 and E2F4 Interact Via Multiple Determinants in Each Protein Academic Article
-
Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase Academic Article
-
IMPACT OF MUTATIONS AT THE P4 AND P5 POSITIONS ON THE REACTION OF ANTITHROMBIN WITH THROMBIN AND ELASTASE Academic Article
-
Identifican of A New High Oxygen Affinity Hemoglobin Variant: Hb Aurora [β139(H17)Asn→Tyr] Academic Article
-
Identification and Characterization of Receptors for Oxytocin in the Myometrium of the Pregnant Ewe Academic Article
-
Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A)
+
RNA Binding Protein Academic Article
-
Identification and characterization of a factor Va-binding site on human prothrombin fragment 2 Academic Article
-
Identification and characterization of a small modular domain in the herpes simplex virus host shutoff protein sufficient for interaction with VP16 Academic Article
-
Identification of Caveolin-1 as a Fatty Acid Binding Protein Academic Article
-
Identification of SVTCG in thrombospondin as the conformation-dependent, high affinity binding site for its receptor, CD36 Academic Article
-
Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2) Academic Article
-
Identification of a common protease-sensitive region in d-alanyl-d-alanine and d-alanyl-d-lactate ligases and photoaffinity labeling with 8-azido ATP Academic Article
-
Identification of a megaplasmid centromere reveals genetic structural diversity within therepABCfamily of basic replicons Academic Article
-
Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase. Academic Article
-
Identification of the Binding Site of Brucella VirB8 Interaction Inhibitors Academic Article
-
Identification of the Catalytic Residues of AroA (Enolpyruvylshikimate 3-Phosphate Synthase) Using Partitioning Analysis Academic Article
-
Identification of the Docking Site between a Type III Secretion System ATPase and a Chaperone for Effector Cargo Academic Article
-
Identification of the Factor VIIa Binding Site on Tissue Factor by Homologous Loop Swap and Alanine Scanning Mutagenesis Academic Article
-
Identification of the MMRN1 Binding Region within the C2 Domain of Human Factor V Academic Article
-
Identification of the Protein C/Activated Protein C Binding Sites on the Endothelial Cell Protein C Receptor Academic Article
-
Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development Academic Article
-
Immunohistochemical analysis based Ep-ICD subcellular localization index (ESLI) is a novel marker for metastatic papillary thyroid microcarcinoma Academic Article
-
In Vitro Selection of New DNA Aptamers for Human Vascular Endothelial Growth Factor 165 Academic Article
-
In vitro and in vivo studies of MutS, MutL and MutH mutants: correlation of mismatch repair and DNA recombination Academic Article
-
In vitro selection of deoxyribozymes with DNA capping activity Academic Article
-
Inactivation of thrombin by antithrombin III on a heparinized biomaterial Academic Article
-
Incorporation of Factor Va into Prothrombinase Is Required for Coordinated Cleavage of Prothrombin by Factor Xa Academic Article
-
Indices for predicting the quality of leaving groups Conference Paper
-
Influence of Particle Size on the Binding Activity of Proteins Adsorbed onto Gold Nanoparticles Academic Article
-
Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release Academic Article
-
Inhibition of Fibrin-Bound Thrombin by a Covalent Antithrombin-Heparin Complex Academic Article
-
Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of α-thrombin Academic Article
-
Inhibition of thrombin by antithrombin III in the presence of certain glycosaminoglycans found in the mammalian aorta Academic Article
-
Inhibitors of ADP-induced platelet aggregation prevent fibrinogen binding to rabbit platelets and cause rapid deaggregation and dissociation of bound fibrinogen Article
-
Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions Academic Article
-
Inscribing the Perimeter of the PagP Hydrocarbon Ruler by Site-Specific Chemical Alkylation Academic Article
-
Interaction between LSD and dopamine D2/3 binding sites in pig brain Academic Article
-
Interaction of D-phenylalanine with Co(II)-substituted rabbit muscle pyruvate kinase: kinetic and optical properties Academic Article
-
Interaction of calcium channel antagonists with calcium: structural studies on verapamil and its Ca2+ complex Academic Article
-
Interaction of histidine-rich glycoprotein with human T lymphocytes Academic Article
-
Interaction of human lactoferrin with the rat liver Academic Article
-
Interaction of substance P and its N- and C-terminal fragments with Ca2+: Implications for hormone action Academic Article
-
Interfacial Membrane Properties Modulate Protein Kinase C Activation: Role of the Position of Acyl Chain Unsaturation Academic Article
-
Intersegment Hydrogen Bonds as Possible Structural Determinants of the N/Q/R Site in Glutamate Receptors Academic Article
-
Inverse agonist binding of peripheral benzodiazepine receptors in anxiety disorder Academic Article
-
Investigating serpin–enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II Academic Article
-
Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases-1 (TIMP-1) transcription Academic Article
-
Irreversible Block of Cardiac Mutant Na+Channels by Batrachotoxin Academic Article
-
Isolation and properties of plasma membrane from smooth muscle. Academic Article
-
Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms Academic Article
-
Kinetics, Stoichiometry, and Identification of the Reactive Thiolate in the Inactivation of UDP-GlcNAc Enolpyruvoyl Transferase by the Antibiotic Fosfomycin Academic Article
-
KvAP-Based Model of the Pore Region of Shaker Potassium Channel Is Consistent with Cadmium- and Ligand-Binding Experiments Academic Article
-
L-Leucinthiol — A potent inhibitor of leucine aminopeptidase Academic Article
-
Lack of specificity of the C3-opsonized zymosan reagent for the assay of membrane complement receptors Academic Article
-
Lectin-binding properties of the Merkel cell and other root sheath cells in perinatal rat vibrissae Academic Article
-
Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin Academic Article
-
Ligand interactions at the active site of aspartate transcarbamoylase from Escherichia coli Academic Article
-
Ligands of Diltiazem Binding Site: An Overview of Some Chemotypes Academic Article
-
Like Fibrin, (DD)E, the Major Degradation Product of Crosslinked Fibrin, Protects Plasmin from Inhibition by α2-antiplasmin Academic Article
-
Linear Free Energy Relationship Analysis of Transition State Mimicry by 3-Deoxy-d-arabino-heptulosonate-7-phosphate (DAHP) Oxime, a DAHP Synthase Inhibitor and Phosphate Mimic Academic Article
-
Lipid Trafficking Controls Endotoxin Acylation in Outer Membranes of Escherichia coli Academic Article
-
Localization and characterization of [125I]iodomelatonin binding sites in duck gonads Academic Article
-
Localization of the Thrombin-binding Domain on Prothrombin Fragment 2 Academic Article
-
Location of the multimerin 1 binding site in coagulation factor V: An update Academic Article
-
Location of two contact sites between human smooth muscle caldesmon and Ca(2+)-calmodulin. Academic Article
-
MCM Proteins Are Associated with RNA Polymerase II Holoenzyme Academic Article
-
Making AppDNA using T4 DNA ligase Academic Article
-
Mapping Allostery through Equilibrium Perturbation NMR Spectroscopy Academic Article
-
Mapping of Steroids Binding to 17β-Hydroxysteroid Dehydrogenase Type 1 Using Monte Carlo Energy Minimization Reveals Alternative Binding Modes Academic Article
-
Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα Academic Article
-
Mapping the Interactions between the Alzheimer’s Aβ-Peptide and Human Serum Albumin beyond Domain Resolution Academic Article
-
Mapping the interaction surface of scorpion β-toxins with an insect sodium channel Academic Article
-
Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13 Academic Article
-
Mechanism of action of the novel plasma membrane Ca2+-pump inhibitor caloxin Academic Article
-
Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase Conference Paper
-
Mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: role of the nucleotide positioning loop Academic Article
-
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants Academic Article
-
Mechanisms Responsible for Catalysis of the Inhibition of Factor Xa or Thrombin by Antithrombin Using a Covalent Antithrombin-Heparin Complex Academic Article
-
Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function Academic Article
-
Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators Academic Article
-
Melatonin receptors in the chicken kidney are up-regulated by pinealectomy and linked to adenylate cyclase Academic Article
-
Melatonin receptors on human granulosa cell membranes. Academic Article
-
Melatonin—A pleiotropic, orchestrating regulator molecule Academic Article
-
Membrane components can modulate the substrate specificity of protein kinase C Academic Article
-
Methods to Validate Binding and Kinetics of “Proximity‐Inducing” Covalent Immune‐Recruiting Molecules Academic Article
-
Microheterogeneity of antithrombin III Academic Article
-
Mineral induction by immobilized phosphoproteins Academic Article
-
Modifications in Perfringolysin O Domain 4 Alter the Cholesterol Concentration Threshold Required for Binding Academic Article
-
Modularity of protein function: Chimeric interleukin 1.beta.s containing specific protease inhibitor loops retain function of both molecules Academic Article
-
Modulating the Activity of Protein Conjugated to Gold Nanoparticles by Site-Directed Orientation and Surface Density of Bound Protein Academic Article
-
Modulation of the Enzymatic Activity of α-Thrombin by Polyanions: Consequences on Intrinsic Activation of Factor V and Factor VIII Academic Article
-
Molecular Basis for the Resistance of Fibrin-Bound Thrombin to Inactivation by Heparin/Serpin Complexes Academic Article
-
Molecular Basis for the Susceptibility of Fibrin-bound Thrombin to Inactivation by Heparin Cofactor II in the Presence of Dermatan Sulfate but Not Heparin Academic Article
-
Molecular Dynamics of Fibrinogen Adsorption onto Graphene, but Not onto Poly(ethylene glycol) Surface, Increases Exposure of Recognition Sites That Trigger Immune Response Academic Article
-
Molecular Mapping of the Thrombin-Heparin Cofactor II Complex Academic Article
-
Molecular Modeling of Benzothiazepine Binding in the L-type Calcium Channel Academic Article
-
Molecular basis of inherited human antithrombin deficiency Academic Article
-
Molecular basis of selective resistance of the bumblebee BiNa
v
1 sodium channel to tau-fluvalinate Academic Article
-
Molecular mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: roles of conserved active site residues Academic Article
-
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice Academic Article
-
Monoamine oxidase inhibitor sensitive site implicated in sensitization to quinpirole Academic Article
-
Monoclonal antibodies to Escherichia coli F1-ATPase. Correlation of binding site location with interspecies cross-reactivity and effects on enzyme activity. Academic Article
-
Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions. Academic Article
-
Mouse NGF promoter upstream sequences do not affect gene expression in mouse fibroblasts Academic Article
-
Multiple [3H]-Oxytocin Binding Sites in Rat Myometrial Plasma Membranes Academic Article
-
Multiple sites and synergism in the binding of inhibitors to microsomal aminopeptidase Academic Article
-
Muscarinic receptor size on smooth muscle cells and membranes Academic Article
-
Mutants of HeLa cells resistant to ouabain and cassaine: Genetic evidence for the common site of action of cardiac glycosides and erythrophleum alkaloids Academic Article
-
Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G Academic Article
-
Myb and Ets related transcription factors are required for activity of the human lck type I promoter. Academic Article
-
NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit Academic Article
-
Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site Academic Article
-
Neotrofin, a novel purine that induces NGF-dependent nociceptive nerve sprouting but not hyperalgesia in adult rat skin Academic Article
-
Nerve growth factor inhibitor with novel-binding domain demonstrates nanomolar efficacy in both cell-based and cell-free assay systems Academic Article
-
Neuroimaging of mirtazapine enantiomers in humans Academic Article
-
Nicotinamide adenine dinucleotide depresses synaptic transmission in the hippocampus and has specific binding sites on the synaptic membranes Academic Article
-
Non-sterol structural probes of the lanosterol 14α-demethylase from Saccharomyces cerevisiae Academic Article
-
Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations Academic Article
-
Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1 Academic Article
-
Nudeocytoplasmic shuttling by protein nuclear import factors Academic Article
-
Oestradiol decreases rat apolipoprotein AI transcription via promoter site B Academic Article
-
On the interaction of rabbit antithrombin III with the luminal surface of the normal and deendothelialized rabbit thoracic aorta in vitro Academic Article
-
Oncostatin M Stimulates c-Fos to Bind a Transcriptionally Responsive AP-1 Element within the Tissue Inhibitor of Metalloproteinase-1 Promoter Academic Article
-
Ontogeny of 2-[125I]iodomelatonin binding sites in the chicken (Gallus domesticus) kidney and spleen Academic Article
-
Overlapping Binding Sites of Structurally Different Antiarrhythmics Flecainide and Propafenone in the Subunit Interface of Potassium Channel Kv2.1* Academic Article
-
PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells Academic Article
-
PagP Crystallized from SDS/Cosolvent Reveals the Route for Phospholipid Access to the Hydrocarbon Ruler Academic Article
-
Paramyxovirus-induced platelet aggregation. Requirement for neuraminic acid receptors on platelets. Academic Article
-
Pervasive Cryptic Epistasis in Molecular Evolution Academic Article
-
Pharmacological characterization of melatonin binding sites in Syrian hamster hypothalamus Academic Article
-
Phenylalkylamines in calcium channels: computational analysis of experimental structures Academic Article
-
Phosphate Analogues as Probes of the Catalytic Mechanisms of MurA and AroA, Two Carboxyvinyl Transferases Academic Article
-
Phosphopeptide Selective Coordination Complexes as Promising Src Homology 2 Domain Mimetics Academic Article
-
Phosphorus-containing inhibitors of aspartate transcarbamoylase fromEscherichia coli Academic Article
-
Phosphorylated Derivatives That Activate or Inhibit Mammalian Adenosine Kinase Provide Insights into the Role of Pentavalent Ions in AK Catalysis Academic Article
-
Photoaffinity labeling of fatty acid-binding proteins involved in long chain fatty acid transport in Escherichia coli. Academic Article
-
Physical Interaction with Human Tumor-derived p53 Mutants Inhibits p63 Activities Academic Article
-
Picomolar-affinity binding and inhibition of adenylate cyclase activity by melatonin in syrian hamster hypothalamus Academic Article
-
PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM Academic Article
-
Platelet IgG Fc receptor Academic Article
-
Platelet imipramine binding is increased in essential thrombocythaemia Academic Article
-
Platelet survival studies. An overview of the factors affecting the efficiency and reliability of platelet radiolabeling Academic Article
-
Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin Academic Article
-
Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences Academic Article
-
Polyomavirus large T antigen binds independently to multiple, unique regions on the viral genome Academic Article
-
Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2 Academic Article
-
Polyphosphate binds with high affinity to exosite II of thrombin Academic Article
-
Position of residues in transmembrane peptides with respect to the lipid bilayer: a combined lipid Noes and water chemical exchange approach in phospholipid bicelles. Academic Article
-
Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives Academic Article
-
Potentialphilicity and potentialphobicity: Reactivity indicators for external potential changes from density functional reactivity theory Academic Article
-
Predicting the reactivity of ambidentate nucleophiles and electrophiles using a single, general-purpose, reactivity indicator Academic Article
-
Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: A CASP‐CAPRI experiment Academic Article
-
Predominant Interactions between μ-Conotoxin Arg-13 and the Skeletal Muscle Na+ Channel Localized by Mutant Cycle Analysis Academic Article
-
Prejunctional muscarinic receptors in the deep muscular plexus of canine ileum: comparison with smooth muscle receptors. Academic Article
-
Primary structure-based function characterization of BRCT domain replicates in BRCA1 Academic Article
-
Probing the "active site" of diamine oxidase: structure-activity relations for histamine potentiation by O-alkylhydroxylamines on colonic epithelium. Academic Article
-
Probing the active site of YjeE: a vital Escherichia coli protein of unknown function Academic Article
-
Production and Characterization of Monoclonal Antibodies to ARVCF Academic Article
-
Protein kinase C: An example of a calcium-regulated protein binding to membranes (Review) Academic Article
-
Pyrazine derivatives affect membrane fluidity of vascular smooth muscle microsomes in relation to their biological activity Academic Article
-
Quality Control Certification of RNA Aptamer-Based Detection Academic Article
-
Quantitative analysis of regions of adenovirus E1A products involved in interactions with cellular proteins Academic Article
-
Quartz crystal microbalance study of protein adsorption kinetics on poly(2-hydroxyethyl methacrylate) Academic Article
-
Rainbow trout exposed to benzo[a]pyrene yields conserved microRNA binding sites in DNA methyltransferases across 500 million years of evolution Academic Article
-
Rapid Evolution of cis-Regulatory Sequences via Local Point Mutations Academic Article
-
Receptor domains of two-component signal transduction systems Academic Article
-
Recognition of Anionic Porphyrins by DNA Aptamers Academic Article
-
Recognition of polyunsaturated acyl chains by enzymes acting on membrane lipids Academic Article
-
Reduction Precedes Cytidylyl Transfer without Substrate Channeling in Distinct Active Sites of the Bifunctional CDP-Ribitol Synthase from Haemophilus influenzae Academic Article
-
Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain Academic Article
-
Related RNA Polymerase-binding Regions in Human RAP30/74 And
Escherichia coli
σ70 Academic Article
-
Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis Academic Article
-
Requirement of Lysine Residues Outside of the Proposed Pentasaccharide Binding Region for High Affinity Heparin Binding and Activation of Human Antithrombin III Academic Article
-
Rifampin phosphotransferase is an unusual antibiotic resistance kinase Academic Article
-
Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation Academic Article
-
Role of dopamine systems in obsessive-compulsive disorder (OCD): implications from a novel psychostimulant-induced animal model. Academic Article
-
Role of mitochondrial calcium transport in failing heart. Academic Article
-
Roles of specific lipid species in the cell and their molecular mechanism Academic Article
-
Rotational Symmetry of Two Pyrethroid Receptor Sites in the Mosquito Sodium Channel Academic Article
-
Ryanodine and the adrenergic, purinergic stimulation in the rat vas deferens smooth muscle: functional and radioligand binding studies. Academic Article
-
Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis Academic Article
-
Secondary structure of charge isomers of myelin basic protein before and after phosphorylation Academic Article
-
Selection of a Suppressor Mutation That Restores Affinity of an Oligonucleotide Inhibitor for Thrombin Using in Vitro Genetics Academic Article
-
Selection of novel, specific single-stranded DNA sequences by Flp, a duplex-specific DNA binding protein Academic Article
-
Selective Cu2+ Binding, Redox Silencing, and Cytoprotective Effects of the Small Heat Shock Proteins αA- and αB-Crystallin Academic Article
-
Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion Academic Article
-
Serine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel Academic Article
-
Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2 Academic Article
-
Simultaneous in vitro assay of the first four enzymes in the fungal aspartate pathway identifies a new class of aspartate kinase inhibitor Academic Article
-
Small-Molecule Screening Made Simple for a Difficult Target with a Signaling Nucleic Acid Aptamer that Reports on Deaminase Activity Academic Article
-
Sodium channel activators: Model of binding inside the pore and a possible mechanism of action Academic Article
-
Solution Studies of Isepamicin and Conformational Comparisons between Isepamicin and Butirosin A When Bound to an Aminoglycoside 6‘-N-Acetyltransferase Determined by NMR Spectroscopy Academic Article
-
Somatostatin Binding Sites in Human and Monkey Brain: Localization and Characterization Academic Article
-
Some experimental approaches for studying subunit interactions in enzymes Academic Article
-
Some observations on the affinity chromatography of rabbit plasminogen Academic Article
-
Species Specificity of Amidine-Based Urokinase Inhibitors Academic Article
-
Specific [3H]-guanosine binding sites in rat brain membranes Academic Article
-
Specific labeling of Candida tropicalis peroxisomal proteins with photoreactive fatty-acid derivatives Academic Article
-
Specificity of Membrane Binding of the Neuronal Protein NAP-22 Academic Article
-
Spectroscopic evidence of interaction between 2-allyl-2-isopropylacetamide and cytochrome P-450 of rat liver microsomes Academic Article
-
Splicing and transcription-associated proteins PSF and p54nrb/NonO bind to the RNA polymerase II CTD Academic Article
-
Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X-linked agammaglobulinemia Academic Article
-
Stereospecific binding sites for [3H]nicotinamide adenine dinucleotide in the rat brain Academic Article
-
Stoichiometry and Affinity of the Human Serum Albumin-Alzheimer's Aβ Peptide Interactions Academic Article
-
Streptomyces IHF uses multiple interfaces to bind DNA Academic Article
-
Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I Academic Article
-
Structural Model for Dihydropyridine Binding to L-type Calcium Channels Academic Article
-
Structural Model for Phenylalkylamine Binding to L-type Calcium Channels Academic Article
-
Structural Studies on Cross-Linked Regions of Elastin Academic Article
-
Structural and Binding Effects of Chemical Modifications on Thrombin Binding Aptamer (TBA) Academic Article
-
Structural and Functional Studies of the Pseudomonas aeruginosa Minor Pilin, PilE Academic Article
-
Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor Academic Article
-
Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase Academic Article
-
Structural basis for streptogramin B resistance in
Staphylococcus aureus
by virginiamycin B lyase Academic Article
-
Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand Academic Article
-
Structural modeling of calcium binding in the selectivity filter of the L-type calcium channel Academic Article
-
Structural requirements for the activation of human factor VIII by thrombin Academic Article
-
Structure and Functional Relationships in Human pur H Academic Article
-
Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase Academic Article
-
Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases Academic Article
-
Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa Academic Article
-
Structure of the Human 3α-Hydroxysteroid Dehydrogenase Type 3 in Complex with Testosterone and NADP at 1.25-Å Resolution Academic Article
-
Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance Academic Article
-
Studies of membrane physical properties and their role in biological function Conference Paper
-
Studies of the Metabolism of Asialotransferrins: The Mechanism for the Hypercatabolism of Human Asialotransferrin in the Rabbit Academic Article
-
Studies of the metabolism of asialotransferrins: nonspecific changes in the metabolic behaviour of human asialotransferrin in avians Academic Article
-
Studies on Protein Subunits. V. Specific Interaction between Matrix–Bound Subunits of Aldolase and Soluble Aldolase Subunits Academic Article
-
Studies on polynucleotides, LXXXIV. On the role of ribosomal subunits in protein synthesis. Academic Article
-
Study of a series of analogs of salmon calcitonin in which alanine replaces leucine Academic Article
-
Subcellular distribution of dihydropyridine isothiocyanate binding in guinea-pig ileal smooth muscle. Academic Article
-
Subcellular-membrane characterization of [3H]ryanodine-binding sites in smooth muscle Academic Article
-
Substrate Chirality and Specificity of Diacylglycerol Kinases and the Multisubstrate Lipid Kinase Academic Article
-
Subunit interactions in aspartate transcarbamylase from Escherichia coli
studied using matrix-bound derivatives Academic Article
-
Subunit interactions in aspartate transcarbamylase. Characterization of a complex between the catalytic and the regulatory subunits Academic Article
-
Synergistic binding of ligands to angiotensin-converting enzyme. Academic Article
-
TATA-binding protein activates transcription when upstream of a GCN4-binding site in a novel yeast promoter. Academic Article
-
Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics Academic Article
-
Targeting of passenger protein domains to multiple intracellular membranes Academic Article
-
Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread Academic Article
-
Tenascin-C Splice Variant Adhesive/anti-Adhesive Effects on Chondrosarcoma Cell Attachment to Fibronectin. Academic Article
-
The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase Academic Article
-
The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals Academic Article
-
The Asp272–Glu282 Region of Platelet Glycoprotein Ibα Interacts with the Heparin-binding Site of α-Thrombin and Protects the Enzyme from the Heparin-catalyzed Inhibition by Antithrombin III Academic Article
-
The Binding of Unfractionated Heparin and Low Molecular Weight Heparin to Thrombin-Activated Human Endothelial Cells Academic Article
-
The BldD Protein from
Streptomyces coelicolor
Is a DNA-Binding Protein Academic Article
-
The C-terminal domain of RNA polymerase II couples mRNA processing to transcription Academic Article
-
The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance Academic Article
-
The DY genes of the cattle MHC: expression and comparative analysis of an unusual class II MHC gene pair Academic Article
-
The Double-Stranded RNA-Binding Protein Staufen Is Incorporated in Human Immunodeficiency Virus Type 1: Evidence for a Role in Genomic RNA Encapsidation Academic Article
-
The Evolutionary Origins of Eukaryotic Protein Disulfide Isomerase Domains: New Evidence from the Amitochondriate Protist Giardia lamblia Academic Article
-
The Guanylyltransferase Domain of Mammalian mRNA Capping Enzyme Binds to the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II Academic Article
-
The Human Enhancer Blocker CTC-binding Factor Interacts with the Transcription Factor Kaiso Academic Article
-
The Influence of Ser-154, Cys-113, and the Phosphorylated Threonine Residue on the Catalytic Reaction Mechanism of Pin1 Academic Article
-
The LysR-type PcaQ protein regulates expression of a protocatechuate-inducible ABC-type transport system in Sinorhizobium meliloti Academic Article
-
The Myxoma Virus-soluble Interferon-
γ Receptor Homolog, M-T7, Inhibits Interferon-
γ in a Species-specific Manner Academic Article
-
The Orphan Nuclear Hormone Receptor LXRα Interacts with the Peroxisome Proliferator-activated Receptor and Inhibits Peroxisome Proliferator Signaling Academic Article
-
The PEA3 Subfamily of Ets Transcription Factors Synergizes with β-Catenin–LEF-1 To Activate Matrilysin Transcription in Intestinal Tumors Academic Article
-
The Selective Cause of an Ancient Adaptation Academic Article
-
The Sinorhizobium meliloti chromosomal origin of replication Academic Article
-
The Structural Integrity of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII Academic Article
-
The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation Academic Article
-
The affinity of human, rabbit and bovine thrombins for sepharose-lysine and other conjugates Academic Article
-
The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand Academic Article
-
The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPβ in v-src transformed chicken embryo fibroblasts Academic Article
-
The effects of the trinitrophenylation of the amino groups of glucagon on its conformational properties and on its ability to activate rat liver adenylyl cyclase Academic Article
-
The epsilon subunit and inhibitory monoclonal antibodies interact with the carboxyl-terminal region of the beta subunit of Escherichia coli F1-ATPase. Academic Article
-
The evolution of the class A scavenger receptors Academic Article
-
The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase Academic Article
-
The membrane bound bacterial lipocalin Blc is a functional dimer with binding preference for lysophospholipids Academic Article
-
The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an active site base important for acetyl transfer Academic Article
-
The p120ctn-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides Academic Article
-
The p56 -interacting Protein p62 Stimulates Transcription via the SV40 Enhancer Academic Article
-
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults Academic Article
-
The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines Academic Article
-
The relevance of the structure of lysine bound to Sepharose for the affinity of rabbit plasminogen Academic Article
-
The role of molybdenum in the synthesis of Neurospora nitrate reductase Academic Article
-
The role of the phospholipid phase transition in the regulation of glucagon binding to lecithin Academic Article
-
The single-stranded DNA aptamer-binding site of human thrombin. Academic Article
-
The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator Academic Article
-
The structure of the apocAMP‐binding domain ofHCN4 – a stepping stone toward understanding thecAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels Academic Article
-
Theoretical study of interaction of winter flounder antifreeze protein with ice Academic Article
-
Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase Academic Article
-
Three functional classes of transcriptional activation domain Academic Article
-
Thrombin Activation of Factor XI on Activated Platelets Requires the Interaction of Factor XI and Platelet Glycoprotein Ibα with Thrombin Anion-binding Exosites I and II, Respectively Academic Article
-
Thrombin Hydrolysis of Human Osteopontin Is Dependent on Thrombin Anion-binding Exosites Academic Article
-
Thrombin Inhibition by Hirudin: How Hirudin Inhibits Thrombin Academic Article
-
Thrombin Interacts with Thrombomodulin, Protein C, and Thrombin-activatable Fibrinolysis Inhibitor via Specific and Distinct Domains Academic Article
-
Thrombin structure and function Academic Article
-
Toward a Detailed Understanding of Base Excision Repair Enzymes: Transition State and Mechanistic Analyses of N-Glycoside Hydrolysis and N-Glycoside Transfer Academic Article
-
Toward an Efficient DNAzyme Academic Article
-
Truncation of the C-Terminal Acidic Transcriptional Activation Domain of Herpes Simplex Virus VP16 Renders Expression of the Immediate-Early Genes Almost Entirely Dependent on ICP0 Academic Article
-
Two Conserved Histidine Residues Are Critical to the Function of the TagF-like Family of Enzymes Academic Article
-
Tyrosine phosphorylation and cadherin/catenin function Academic Article
-
Ultrasonic and Densimetric Characterization of the Association of Cyclic AMP with the cAMP-Binding Domain of the Exchange Protein EPAC1 Academic Article
-
Unfolding of Acrylodan-Labeled Human Serum Albumin Probed by Steady-State and Time-Resolved Fluorescence Methods Academic Article
-
Unraveling Determinants of Affinity Enhancement in Dimeric Aptamers for a Dimeric Protein Academic Article
-
Unraveling the Complexities of DNA-Dependent Protein Kinase Autophosphorylation Academic Article
-
Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain Academic Article
-
Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface Academic Article
-
Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure Academic Article
-
Zn2+ Mediates High Affinity Binding of Heparin to the αC Domain of Fibrinogen Academic Article
-
[10] Archaeal histones and nucleosomes Book
-
[Enhanced translational efficacy of internal ribosomal entry site-mediated mRNA in dendritic cells contributes to efficient induction of antitumor immunity]. Academic Article
-
[Molecular physiology of adrenoreceptors]. Academic Article
-
[Productive conformations of ligands and topography of the alpha1-adrenoreceptor active site based on theoretical conformation analysis]. Academic Article
-
[Theoretical conformational analysis of methylamide N-acetyl-L-arginine]. Academic Article
-
[Topography of the active site of the noradrenaline neuronal membrane carrier based on the theoretical conformation analysis of inhibitors of neuronal catecholamine uptake]. Academic Article
-
cAMP activation of PKA defines an ancient signaling mechanism Academic Article
-
p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor Academic Article
-
α-Adrenoceptors in Dog Mesenteric Vessels–Subcellular Distribution and Number of [3H]Prazosin and [3H]Rauwolscine Binding Sites Academic Article