Binding Sites Concept

subject area of

• 2-[¹²⁵I]Iodomelatonin Binding in the Brains of Four Salmonids  Academic Article
• 2-[¹²⁵l]lodomelatonin Binding Sites in the Lung and Heart: A Link between the Photoperiodic Signal, Melatonin, and the Cardiopulmonary System  Academic Article
• 2-[125I]Iodomelatonin binding sites in the quail heart: Characteristics, distribution and modulation by guanine nucleotides and cations  Academic Article
• 2-[125I]iodomelatonin-binding sites in the human kidney and the effect of guanosine 5'-O-(3-thiotriphosphate).  Academic Article
• 3 minutes to precisely measure morphogen concentration  Academic Article
• 3-[(3-Cholamidopropyl)dimethylammonio]-1-Propane Sulfonate-Solubilized Binding Sites for 2-[¹²⁵I]Iodomelatonin in Chick Brain Retain Sensitivity to Guanine Nucleotides  Academic Article
• 5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II  Academic Article
• Molecular characterization of the Pseudomonas aeruginosa serotype O5 (PAO1) B-band lipopolysaccharide gene cluster  Academic Article
• Campylobacter jejuni KDO8P Synthase, Its Inhibition by KDO8P Oxime, and Control of the Residence Time of Slow-Binding Inhibition  Academic Article
• In vivo and in vitro Validation of Reference Tissue Models for the mGluR₅ Ligand [¹¹C]ABP688  Academic Article
• A 2.13 Å Structure of E. coli Dihydrofolate Reductase Bound to a Novel Competitive Inhibitor Reveals a New Binding Surface Involving the M20 Loop Region  Academic Article
• A Complex between the Catalytic and Regulatory Subunits of Aspartate Transcarbamylase  Academic Article
• A Deoxyribozyme with a Novel Guanine Quartet-Helix Pseudoknot Structure  Academic Article
• A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP  Academic Article
• A New Target for Antibiotic Development  Academic Article
• A Novel Double-stranded RNA-binding Protein, Disco Interacting Protein 1 (DIP1), Contributes to Cell Fate Decisions during Drosophila Development  Academic Article
• A Small Molecule Discrimination Map of the Antibiotic Resistance Kinome  Academic Article
• A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection  Academic Article
• A human XRCC4–XLF complex bridges DNA  Academic Article
• A hydrocarbon ruler measures palmitate in the enzymatic acylation of endotoxin  Academic Article
• A molecular defect in two families with hemolytic poikilocytic anemia: reduction of high affinity membrane binding sites for ankyrin.  Academic Article
• A monoclonal antibody against activated protein C allows rapid detection of activated protein C in plasma and reveals a calcium ion dependent epitope involved in factor Va inactivation  Academic Article
• A neurochemical basis for the antipsychotic activity of loxapine: interactions with dopamine D1, D2, D4 and serotonin 5-HT2 receptor subtypes.  Academic Article
• A novel Myb-related protein involved in transcriptional activation of encystation genes in Giardia lamblia  Academic Article
• A p56 Ligand Serves as a Coactivator of an Orphan Nuclear Hormone Receptor  Academic Article
• A peptide derived from a tissue factor loop region functions as a tissue factor-factor VIIa antagonist  Academic Article
• A role for the ETS domain transcription factor PEA3 in myogenic differentiation  Academic Article
• AMP inhibition of reactions of ADP with washed platelets from humans and rabbits  Article
• AMP-Activated Protein Kinase-Regulated Activation of the PGC-1α Promoter in Skeletal Muscle Cells  Academic Article
• AMP-activated protein kinase: the current landscape for drug development  Academic Article
• Abnormal hemostasis in a knock‐in mouse carrying a variant of factor IX with impaired binding to collagen type IV  Academic Article
• Access and Binding of Local Anesthetics in the Closed Sodium Channel  Academic Article
• Acetyltransfer Precedes Uridylyltransfer in the Formation of UDP-N-acetylglucosamine in Separable Active Sites of the Bifunctional GlmU Protein of Escherichia coli  Academic Article
• Acidic pH changes receptor binding specificity of Helicobacter pylori: a binary adhesion model in which surface heat shock (stress) proteins mediate sulfatide recognition in gastric colonization  Academic Article
• Activation and Active Site Occupation Alter Conformation in the Region of the First Epidermal Growth Factor-like Domain of Human Factor VII  Academic Article
• Activation of a recombinant human factor VII structural analogue alters its affinity of binding to tissue factor  Academic Article
• Activation of theWT1tumor suppressor gene promoter by Pea3  Academic Article
• Active Site Interference and Asymmetric Activation in the Chemotaxis Protein Histidine Kinase CheA  Academic Article
• Active Subunits of Transaldolase Bound to Sepharose  Academic Article
• Active site labeling of the gentamicin resistance enzyme AAC(6')-APH(2") by the lipid kinase inhibitor wortmannin  Academic Article
• Active-Site Labeling of an Aminoglycoside Antibiotic Phosphotransferase (APH(3')-IIIa)  Academic Article
• Adsorption of Fibrinogen and Lysozyme on Silicon Grafted with Poly(2-methacryloyloxyethyl Phosphorylcholine) via Surface-Initiated Atom Transfer Radical Polymerization  Academic Article
• Affinity chromatography of a regulatory enzyme based on specific interaction with the effector  Academic Article
• Alanine to valine substitutions in the pore helix IIIP1 and linker-helix IIIL45 confer cockroach sodium channel resistance to DDT and pyrethroids  Academic Article
• AlgK Is a TPR-Containing Protein and the Periplasmic Component of a Novel Exopolysaccharide Secretin  Academic Article
• Alignment/Phylogeny of the Papain Superfamily of Cysteine Proteases  Academic Article
• Alpha-2 adrenoceptors on nerves and muscles of rat uterus.  Academic Article
• Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis  Academic Article
• An Extensive Interaction Interface between Thrombin and Factor V Is Required for Factor V Activation  Academic Article
• An alternative pathway for expression of p56lck from type I promoter transcripts in colon carcinoma  Academic Article
• Androgen Receptors in Prostatic Tissue: Evaluation of Systematic Errors and Comparison of Three Procedures to Correct for Nonspecific Binding Sites in the Binding Assays  Academic Article
• Antibiotic stops ‘ping-pong’ match  Academic Article
• Antibodies to Indolealkylamines; Serotonin and Melatonin  Academic Article
• Antithrombin-III-Hamilton: a gene with a point mutation (guanine to adenine) in codon 382 causing impaired serine protease reactivity  Academic Article
• Application of Combinatorial Libraries and Protein Engineering to the Discovery of Novel Anti-Thrombotic Drugs  Conference Paper
• Architecture and Pore Block of Eukaryotic Voltage-Gated Sodium Channels in View of NavAb Bacterial Sodium Channel Structure  Academic Article
• Architecture of the Neuronal Nicotinic Acetylcholine Receptor Ion Channel at the Binding Site of bis-Ammonium Blockers  Academic Article
• Association Analysis Indicates That a Variant GATA-Binding Site in the PIK3CB Promoter Is a Cis-Acting Expression Quantitative Trait Locus for This Gene and Attenuates Insulin Resistance in Obese Children  Academic Article
• Asthma caused by occupational exposure to a furan-based binder system  Academic Article
• Asymmetric distribution of sites with high affinity for antithrombin III in rat skin heparin proteoglycans.  Academic Article
• Atomic determinants of state-dependent block of sodium channels by charged local anesthetics and benzocaine  Academic Article
• Atomic resolution structure of obelin: soaking with calcium enhances electron density of the second oxygen atom substituted at the C2-position of coelenterazine  Academic Article
• Autoradiographic Localization of Human Calcitonin Sensitive Binding Sites in Rat Brain.  Academic Article
• BCL11A represses HBG transcription in K562 cells  Academic Article
• Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA  Academic Article
• Batrachotoxin, Pyrethroids, and BTG 502 Share Overlapping Binding Sites on Insect Sodium Channels  Academic Article
• Batroxobin Binds Fibrin with Higher Affinity and Promotes Clot Expansion to a Greater Extent than Thrombin  Academic Article
• Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax  Academic Article
• Benzodiazepine-induced inhibition of human malignant melanoma (M-6) cell growth.  Academic Article
• Beta adrenoreceptor in vascular smooth muscle with special reference to subcellular localization and number of binding sites.  Academic Article
• Bifunctional Catalysis by CDP-ribitol Synthase:  Convergent Recruitment of Reductase and Cytidylyltransferase Activities in Haemophilus influenzae and Staphylococcus aureus  Academic Article
• Binding Site Determinants for the LysR-Type Transcriptional Regulator PcaQ in the Legume Endosymbiont Sinorhizobium meliloti  Academic Article
• Binding of Aggregated Immunoglobulins to the Human Platelet Fc Receptors: A Mechanism of Platelet to Platelet Bridging  Academic Article
• Binding of Heparin to Metals  Academic Article
• Binding of NAP-22, a Calmodulin-Binding Neuronal Protein, to Raft-like Domains in Model Membranes  Academic Article
• Binding of Thrombin to the G-protein-linked Receptor, and Not to Glycoprotein Ib, Precedes Thrombin-mediated Platelet Activation  Academic Article
• Binding of a glucagon photoaffinity label to rat liver plasma membranes and its effect on adenylate cyclase activity before and after photolysis  Academic Article
• Binding of progesterone to cell surfaces of human granulosa-lutein cells  Academic Article
• Bivalent Binding to γA/γ′-Fibrin Engages Both Exosites of Thrombin and Protects It from Inhibition by the Antithrombin-Heparin Complex  Academic Article
• Bivalent direct thrombin inhibitors: hirudin and bivalirudin  Academic Article
• Borate Binding to Polyol-Stabilized Latex  Academic Article
• Breast cancer prognostic significance of a single nucleotide polymorphism in the proximal androgen response element of the prostate specific antigen gene promoter  Academic Article
• C/EBPβ (NF-M) Is Essential for Activation of the p20K Lipocalin Gene in Growth-Arrested Chicken Embryo Fibroblasts  Academic Article
• CD23-Mediated IgE Transport Across Human Intestinal Epithelium: Inhibition by Blocking Sites of Translation or Binding  Academic Article
• CD36 peptides enhance or inhibit CD36-thrombospondin binding. A two-step process of ligand-receptor interaction.  Academic Article
• CNS Dopamine Receptors: Effect of Prolyl-Leucyl-Glycinamide and Solubilization  Academic Article
• Ca2+ and Zn2+ binding properties of peptide substrates of vertebrate collagenase, MMP-1  Academic Article
• Ca2+-dependent Antifreeze Proteins  Academic Article
• Calcium binding and translocation properties of glucagon and its fragments  Academic Article
• Calcium-channel antagonist binding to isolated vascular smooth muscle membranes  Academic Article
• Calreticulin modulates the in vitro DNA binding but not the in vivo transcriptional activation by peroxisome proliferator-activated receptor/retinoid X receptor heterodimers  Academic Article
• Capillary-Scale Frontal Affinity Chromatography/MALDI Tandem Mass Spectrometry Using Protein-Doped Monolithic Silica Columns  Academic Article
• Carbamoylphosphate requirement for synthesis of the active center of [NiFe]-hydrogenases  Academic Article
• Carbohydrate-binding Modules Recognize Fine Substructures of Cellulose  Academic Article
• ChIP-on-Chip Analysis of In Vivo Mutant p53 Binding To Selected Gene Promoters  Academic Article
• Change of Conformation of the DNA-binding Domain of p53 Is the Only Key Element for Binding of and Interference with p73  Academic Article
• Characterization of protein-DNA interactions within the peroxisome proliferator-responsive element of the rat hydratase-dehydrogenase gene  Academic Article
• Characterization of specific GTP binding sites in C2C12 mouse skeletal muscle cells.  Academic Article
• Characterization of the calcium-binding site that regulates association of protein kinase C with phospholipid bilayers.  Academic Article
• Characterization of the mouse lysosomal sialidase promoter  Academic Article
• Characterization of the pancreatic hormones from the Brockmann body of the tilapia: implications for islet xenograft studies  Academic Article
• Chemical modification reveals involvement of tyrosine in ligand binding to dopamine D1 and D2 receptors.  Academic Article
• Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling.  Academic Article
• Chlamydia Outer Protein (Cop) B from Chlamydia pneumoniae possesses characteristic features of a type III secretion (T3S) translocator protein  Academic Article
• Chlamydia pneumoniae CopD Translocator Protein Plays a Critical Role in Type III Secretion (T3S) and Infection  Academic Article
• Chloride Channels of Glycine and GABA Receptors with Blockers: Monte Carlo Minimization and Structure-Activity Relationships  Academic Article
• Cholesterol Binding Does Not Predict Activity of the Steroidogenic Acute Regulatory Protein, StAR  Academic Article
• Chromanol 293B Binding in KCNQ1 (Kv7.1) Channels Involves Electrostatic Interactions with a Potassium Ion in the Selectivity Filter  Academic Article
• Cleavage-dependent Ligation by the FLP Recombinase  Academic Article
• Cloning and Sequencing of the Cellular–Viral Junctions from the Human Adenovirus Type 5 Transformed 293 Cell Line  Academic Article
• Cognitive impairments of alcoholic cirrhotic patients: correlation with endogenous benzodiazepine receptor ligands and increased affinity of platelet receptors.  Academic Article
• Cold-Active Winter Rye Glucanases with Ice-Binding Capacity  Academic Article
• Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations  Academic Article
• Comparison of the Effects of Heparin and Hirudin on Thrombin Binding to the Normal and the De-Endothelialized Rabbit Aorta In Vitro  Academic Article
• Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.  Academic Article
• Complex formation of platelet thrombospondin with histidine-rich glycoprotein.  Academic Article
• Complex formation of platelet thrombospondin with plasminogen. Modulation of activation by tissue activator.  Academic Article
• Composite Active Site of an ABC ATPase  Academic Article
• Computational Analysis of the Crystal and Cryo-EM Structures of P-Loop Channels with Drugs  Academic Article
• Computational Structural Pharmacology and Toxicology of Voltage-Gated Sodium Channels  Chapter
• Conformational Analysis of Free and Ca²⁺-bound forms of Verapamil and Methoxyverapamil  Academic Article
• Conformational Studies on Calcium Binding BytBoc-Leu-Pro-Tyr-Ala-NHCH₃, a Tyrosine Kinase Substrate, in a Nonpolar Solvent  Academic Article
• Conformational analysis of d-tubocurarine: Implications for minimal dimensions of its binding site within ion channels  Academic Article
• Conformational and biological properties of a covalently linked dimer of glucagon Reaction of mono- and bifunctional sulfenyl halides  Academic Article
• Conformational studies on analogs of recombinant parathyroid hormone and  Academic Article
• Conserved Features and Evolutionary Shifts of the EDA Signaling Pathway Involved in Vertebrate Skin Appendage Development  Academic Article
• Construction of a recombinant adenovirus for efficient delivery of the I-Scel yeast endonuclease to human cells and its application in the in vivo cleavage of chromosomes to expose new potential telomeres  Academic Article
• Control of sarcoplasmic/endoplasmic-reticulum Ca2+ pump expression in cardiac and smooth muscle  Academic Article
• Cooperativity of papain-substrate interaction energies in the S2 to S2' subsites  Academic Article
• Cowden Syndrome–Affected Patients with PTEN Promoter Mutations Demonstrate Abnormal Protein Translation  Academic Article
• Cross-chimeric analysis of selectivity of secretin and VPAC(1) receptor activation.  Academic Article
• Crp Is a Global Regulator of Antibiotic Production in Streptomyces  Academic Article
• Crystal Structure of Anticoagulant Thrombin Variant E217K Provides Insights into Thrombin Allostery  Academic Article
• Crystal Structure of Homoserine Transacetylase from Haemophilus influenzae Reveals a New Family of α/β-Hydrolases^,  Academic Article
• Crystal Structure of Human XLF: A Twist in Nonhomologous DNA End-Joining  Academic Article
• Crystal structure of the DdrB/ssDNA complex from Deinococcus radiodurans reveals a DNA binding surface involving higher-order oligomeric states  Academic Article
• Crystal structure of the Xrcc4 DNA repair protein and implications for end joining  Academic Article
• Crystal structures of homoserine dehydrogenase suggest a novel catalytic mechanism for oxidoreductases  Academic Article
• Crystallization of the DdrB–DNA complex fromDeinococcus radiodurans  Academic Article
• Crystals of modified bovine neurophysin II  Academic Article
• Cytokine-Induced Hepatic Apoptosis Is Dependent on FGL2/Fibroleukin: The Role of Sp1/Sp3 and STAT1/PU.1 Composite cis Elements  Academic Article
• DELPHI: accurate deep ensemble model for protein interaction sites prediction  Academic Article
• DNA Mismatch Repair: From Structure to Mechanism  Academic Article
• Dabigatran and Argatroban Diametrically Modulate Thrombin Exosite Function  Academic Article
• Defining the heparin-binding domain of antithrombin  Academic Article
• Defining the sequence specificity of theSaccharomyces cerevisiae DNA binding protein REB1p by selecting binding sites from random-sequence oligonucleotides  Academic Article
• Definition of an electrostatic relay switch critical for the cAMP-dependent activation of protein kinase A as revealed by the D170A mutant of RIα  Academic Article
• Delineating domains and functions of NUP98 contributing to the leukemogenic activity of NUP98-HOX fusions  Academic Article
• Design and Synthesis of Photoaffinity-Labeling Ligands of the l-Prolyl-l-leucylglycinamide Binding Site Involved in the Allosteric Modulation of the Dopamine Receptor  Academic Article
• Design of Novel Rho Kinase Inhibitors Using Energy Based Pharmacophore Modeling, Shape-Based Screening, in Silico Virtual Screening, and Biological Evaluation  Academic Article
• Design of a protein-targeted DNA aptamer using atomistic simulation  Academic Article
• Detection and Characterization of a Phospholactoyl-Enzyme Adduct in the Reaction Catalyzed by UDP-N-acetylglucosamine Enolpyruvoyl Transferase, MurZ  Academic Article
• Determinants for calcitonin analog interaction with the calcitonin receptor N-terminus and transmembrane-loop regions.  Academic Article
• Determination of Strong Ligand Sites in Sewage Effluent-Impacted Waters by Competitive Ligand Titration with Silver  Academic Article
• Determination of the molecular states of the processive endocellulase Thermobifida fusca Cel9A during crystalline cellulose depolymerization  Academic Article
• Determination of the native form of FadD, the Escherichia coli fatty acyl-CoA synthetase, and characterization of limited proteolysis by outer membrane protease OmpT  Academic Article
• Different binding sites for the neuropeptide Y Y1 antagonists 1229U91 and J-104870 on human Y1 receptors  Academic Article
• Differential Effects of Short Photoperiod on 2-[¹²⁵l]lodomelatonin Binding in the Testis and Brain of Quail  Academic Article
• Dimensions of the ion channel in neuronal nicotinic acetylcholine receptor as estimated from analysis of conformation-activity relationships of open-channel blocking drugs  Academic Article
• Dimeric c-di-GMP Is Required for Post-translational Regulation of Alginate Production in Pseudomonas aeruginosa  Academic Article
• Dissociation of Thrombin's Substrate Interactions Using Site-Directed Mutagenesis  Academic Article
• Distinct surfaces on Cdc5/PLK Polo-box domain orchestrate combinatorial substrate recognition during cell division  Academic Article
• Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography  Academic Article
• Diverse peroxisome proliferator-activated receptors bind to the peroxisome proliferator-responsive elements of the rat hydratase/dehydrogenase and fatty acyl-CoA oxidase genes but differentially induce expression.  Academic Article
• Docking flexible ligands in proteins with a solvent exposure- and distance-dependent dielectric function  Academic Article
• Docking of calcium ions in proteins with flexible side chains and deformable backbones  Academic Article
• Domain Mapping of Heat Shock Protein 70 Reveals That Glutamic Acid 446 and Arginine 447 Are Critical for Regulating Superoxide Dismutase 2 Function  Academic Article
• Drugs acting at the glycine site on the NMDA receptor as cognitive enhancers in patients with Alzheimer's disease  Academic Article
• Dynamics of interacting edge defects in copolymer lamellae  Academic Article
• Dynamin Interacts with Members of the Sumoylation Machinery  Academic Article
• ETS Proteins and MMPs: Partners in Invasion and Metastasis  Academic Article
• Effects of Cu Ions and Explicit Water Molecules on the Copper Binding Domain of Amyloid Precursor Protein APP(131–189): A Molecular Dynamics Study  Academic Article
• Effects of increasing hydrophobicity on the physical-chemical and biological properties of a class A amphipathic helical peptide  Academic Article
• Electron spin resonance spectroscopy reveals alpha-phenyl-N-tert-butylnitrone spin-traps free radicals in rat striatum and prevents haloperidol-induced vacuous chewing movements in the rat model of human tardive dyskinesia  Academic Article
• Eliminating Competition: Characterizing and Eliminating Competitive Binding at Separate Sites between DAHP Synthase’s Essential Metal Ion and the Inhibitor DAHP Oxime  Academic Article
• Elucidation of pyrethroid and DDT receptor sites in the voltage-gated sodium channel  Academic Article
• Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors  Academic Article
• Enhanced binding of fibrinogen by the subendothelium after treatment of the rabbit aorta with thrombin.  Academic Article
• Enolpyruvyl Activation by Enolpyruvylshikimate-3-phosphate Synthase  Academic Article
• Enzyme-assisted suicide: molecular basis for the antifungal activity of 5-hydroxy-4-oxonorvaline by potent inhibition of homoserine dehydrogenase  Academic Article
• Establishing the Principles of Recognition in the Adenine-Binding Region of an Aminoglycoside Antibiotic Kinase [APH(3‘)-IIIa]  Academic Article
• Estrogen and progesterone binding sites in renal cell carcinoma  Academic Article
• Evaluation of DNA aptamers directed to thrombin as potential thrombus imaging agents  Academic Article
• Evaluation of the Calmodulin-SOX9 Interaction by “Magnetic Fishing” Coupled to Mass Spectrometry  Academic Article
• Evidence That Both Exosites on Thrombin Participate in Its High Affinity Interaction with Fibrin  Academic Article
• Evidence for Allosteric Linkage between Exosites 1 and 2 of Thrombin  Academic Article
• Evidence for Calcitonin Receptor Heterogeneity: Binding Studies with Nonhelical Analogs*  Academic Article
• Evidence for Dual Binding Sites for 1,1,1-Trichloro-2,2-bis(p-chlorophenyl)ethane (DDT) in Insect Sodium Channels  Academic Article
• Evidence for Multiple Mechanisms for Membrane Binding and Integration via Carboxyl-Terminal Insertion Sequences  Academic Article
• Evidence for thrombin binding to dermatan sulphate sites in the rabbit aorta subendothelium in vitro  Academic Article
• Evolutionary and Functional Analyses of the Interaction between the Myeloid Restriction Factor SAMHD1 and the Lentiviral Vpx Protein  Academic Article
• Expression of nanomolar-affinity binding sites for melatonin in Syrian hamster RPMI 1846 melanoma cells  Academic Article
• Extension of the Single Amino Acid Chelate Concept (SAAC) to Bifunctional Biotin Analogues for Complexation of the M(CO)₃⁺¹ Core (M = Tc and Re):  Syntheses, Characterization, Biotinidase Stability, and Avidin Binding  Academic Article
• Extracellular guanosine 5′ triphosphate enhances nerve growth factor-induced neurite outgrowth via increases in intracellular calcium  Academic Article
• Factor XIIIa Mediated Attachment of S. aureus Fibronectin-Binding Protein A (FnbA) to Fibrin:  Identification of Gln103 as a Major Cross-Linking Site  Academic Article
• Folded cavity SOI microring sensors for high sensitivity and real time measurement of biomolecular binding  Academic Article
• Folding similarity of the outer pore region in prokaryotic and eukaryotic sodium channels revealed by docking of conotoxins GIIIA, PIIIA, and KIIIA in a NavAb-based model of Nav1.4  Academic Article
• Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae  Academic Article
• Functional implications of mutations within polyomavirus large T antigen Rb-binding domain: effects on pRb and p107 binding in vitro and immortalization activity in vivo  Academic Article
• GTP modulates [125I]iodomelatonin binding to a picomolar-affinity site in the Syrian hamster hypothalamus  Academic Article
• Gauging a Hydrocarbon Ruler by an Intrinsic Exciton Probe  Academic Article
• General occurrence of binding synergism in zinc proteases and its possible significance  Academic Article
• Genome prediction of PhoB regulated promoters in Sinorhizobium meliloti and twelve proteobacteria  Academic Article
• Giardia lamblia RNA Polymerase II  Academic Article
• Glycosaminoglycans Bind Factor Xa in a Ca²⁺-Dependent Fashion and Modulate Its Catalytic Activity  Academic Article
• HD1, a Thrombin-directed Aptamer, Binds Exosite 1 on Prothrombin with High Affinity and Inhibits Its Activation by Prothrombinase  Academic Article
• HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions  Academic Article
• HSP47: a potential target for fibrotic diseases and implications for therapy  Academic Article
• Hemagglutinin sequence clusters and the antigenic evolution of influenza A virus  Academic Article
• Hemoglobin Binding by Enzymatic Fragments of Haptoglobin  Academic Article
• Heparin binds to human monocytes and modulates their procoagulant activities and secretory phenotypes. Effects of histidine-rich glycoprotein  Academic Article
• Heparin enhances active site-dependent binding of tissue-type plasminogen activator to endothelial cells  Academic Article
• Heparin/Heparan Sulfate (HP/HS) Interacting Protein (HIP) Supports Cell Attachment and Selective, High Affinity Binding of HP/HS  Academic Article
• High Temperature Stabilization of DNA in Complexes with Cationic Lipids  Academic Article
• High affinity Ca-binding to smooth muscle plasma membrane: Inhibition by cations  Academic Article
• High frequency recombination betweenloxP sites in human chromosomes mediated by an adenovirus vector expressing Cre recombinase  Academic Article
• High throughput protease profiling comprehensively defines active site specificity for thrombin and ADAMTS13  Academic Article
• High-mobility group box 1 links sensing of reactive oxygen species by huntingtin to its nuclear entry  Academic Article
• Histidine-rich Glycoprotein Binds Fibrin(ogen) with High Affinity and Competes with Thrombin for Binding to the γ′-Chain  Academic Article
• Homology Model of Dihydropyridine Receptor: Implications for L-type Ca2+ Channel Modulation by Agonists and Antagonists  Academic Article
• Homology Models of μ-Opioid Receptor with Organic and Inorganic Cations at Conserved Aspartates in the Second and Third Transmembrane Domains  Academic Article
• Homology Requirements for Ligation and Strand Exchange by the FLP Recombinase  Academic Article
• Host Cell Factor-1 and E2F4 Interact Via Multiple Determinants in Each Protein  Academic Article
• Hypersulfated Low Molecular Weight Heparin with Reduced Affinity for Antithrombin Acts as an Anticoagulant by Inhibiting Intrinsic Tenase and Prothrombinase  Academic Article
• IMPACT OF MUTATIONS AT THE P4 AND P5 POSITIONS ON THE REACTION OF ANTITHROMBIN WITH THROMBIN AND ELASTASE  Academic Article
• Identifican of A New High Oxygen Affinity Hemoglobin Variant: Hb Aurora [β139(H17)Asn→Tyr]  Academic Article
• Identification and Characterization of Receptors for Oxytocin in the Myometrium of the Pregnant Ewe  Academic Article
• Identification and Functional Characterization of a Novel Nuclear Localization Signal Present in the Yeast Nab2 Poly(A) ⁺ RNA Binding Protein  Academic Article
• Identification and characterization of a factor Va-binding site on human prothrombin fragment 2  Academic Article
• Identification and characterization of a small modular domain in the herpes simplex virus host shutoff protein sufficient for interaction with VP16  Academic Article
• Identification of Caveolin-1 as a Fatty Acid Binding Protein  Academic Article
• Identification of SVTCG in thrombospondin as the conformation-dependent, high affinity binding site for its receptor, CD36  Academic Article
• Identification of Synthetic Peptides that Inhibit Lipopolysaccharide (LPS) Binding to Myeloid Differentiation Protein-2 (MD-2)  Academic Article
• Identification of a common protease-sensitive region in d-alanyl-d-alanine and d-alanyl-d-lactate ligases and photoaffinity labeling with 8-azido ATP  Academic Article
• Identification of a megaplasmid centromere reveals genetic structural diversity within therepABCfamily of basic replicons  Academic Article
• Identification of a peroxisome proliferator-responsive element upstream of the gene encoding rat peroxisomal enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase.  Academic Article
• Identification of the Binding Site of Brucella VirB8 Interaction Inhibitors  Academic Article
• Identification of the Catalytic Residues of AroA (Enolpyruvylshikimate 3-Phosphate Synthase) Using Partitioning Analysis  Academic Article
• Identification of the Docking Site between a Type III Secretion System ATPase and a Chaperone for Effector Cargo  Academic Article
• Identification of the Factor VIIa Binding Site on Tissue Factor by Homologous Loop Swap and Alanine Scanning Mutagenesis  Academic Article
• Identification of the MMRN1 Binding Region within the C2 Domain of Human Factor V  Academic Article
• Identification of the Protein C/Activated Protein C Binding Sites on the Endothelial Cell Protein C Receptor  Academic Article
• Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development  Academic Article
• Immunohistochemical analysis based Ep-ICD subcellular localization index (ESLI) is a novel marker for metastatic papillary thyroid microcarcinoma  Academic Article
• In Vitro Selection of New DNA Aptamers for Human Vascular Endothelial Growth Factor 165  Academic Article
• In vitro and in vivo studies of MutS, MutL and MutH mutants: correlation of mismatch repair and DNA recombination  Academic Article
• In vitro selection of deoxyribozymes with DNA capping activity  Academic Article
• Inactivation of thrombin by antithrombin III on a heparinized biomaterial  Academic Article
• Incorporation of Factor Va into Prothrombinase Is Required for Coordinated Cleavage of Prothrombin by Factor Xa  Academic Article
• Indices for predicting the quality of leaving groups  Conference Paper
• Influence of Particle Size on the Binding Activity of Proteins Adsorbed onto Gold Nanoparticles  Academic Article
• Inhibition of AMP-Activated Protein Kinase at the Allosteric Drug-Binding Site Promotes Islet Insulin Release  Academic Article
• Inhibition of Fibrin-Bound Thrombin by a Covalent Antithrombin-Heparin Complex  Academic Article
• Inhibition of the amplification reactions of blood coagulation by site-specific inhibitors of α-thrombin  Academic Article
• Inhibition of thrombin by antithrombin III in the presence of certain glycosaminoglycans found in the mammalian aorta  Academic Article
• Inhibitors of ADP-induced platelet aggregation prevent fibrinogen binding to rabbit platelets and cause rapid deaggregation and dissociation of bound fibrinogen  Article
• Inositol pentakisphosphate isomers bind PH domains with varying specificity and inhibit phosphoinositide interactions  Academic Article
• Inscribing the Perimeter of the PagP Hydrocarbon Ruler by Site-Specific Chemical Alkylation  Academic Article
• Interaction between LSD and dopamine D2/3 binding sites in pig brain  Academic Article
• Interaction of D-phenylalanine with Co(II)-substituted rabbit muscle pyruvate kinase: kinetic and optical properties  Academic Article
• Interaction of calcium channel antagonists with calcium: structural studies on verapamil and its Ca2+ complex  Academic Article
• Interaction of histidine-rich glycoprotein with human T lymphocytes  Academic Article
• Interaction of human lactoferrin with the rat liver  Academic Article
• Interaction of substance P and its N- and C-terminal fragments with Ca2+: Implications for hormone action  Academic Article
• Interfacial Membrane Properties Modulate Protein Kinase C Activation:  Role of the Position of Acyl Chain Unsaturation  Academic Article
• Intersegment Hydrogen Bonds as Possible Structural Determinants of the N/Q/R Site in Glutamate Receptors  Academic Article
• Inverse agonist binding of peripheral benzodiazepine receptors in anxiety disorder  Academic Article
• Investigating serpin–enzyme complex formation and stability via single and multiple residue reactive centre loop substitutions in heparin cofactor II  Academic Article
• Involvement of AP1 and PEA3 binding sites in the regulation of murine tissue inhibitor of metalloproteinases-1 (TIMP-1) transcription  Academic Article
• Irreversible Block of Cardiac Mutant Na⁺Channels by Batrachotoxin  Academic Article
• Isolation and properties of plasma membrane from smooth muscle.  Academic Article
• Kaiso Represses the Cell Cycle Gene cyclin D1 via Sequence-Specific and Methyl-CpG-Dependent Mechanisms  Academic Article
• Kinetics, Stoichiometry, and Identification of the Reactive Thiolate in the Inactivation of UDP-GlcNAc Enolpyruvoyl Transferase by the Antibiotic Fosfomycin  Academic Article
• KvAP-Based Model of the Pore Region of Shaker Potassium Channel Is Consistent with Cadmium- and Ligand-Binding Experiments  Academic Article
• L-Leucinthiol — A potent inhibitor of leucine aminopeptidase  Academic Article
• Lack of specificity of the C3-opsonized zymosan reagent for the assay of membrane complement receptors  Academic Article
• Lectin-binding properties of the Merkel cell and other root sheath cells in perinatal rat vibrissae  Academic Article
• Life-Threatening Thrombosis in Mice With Targeted Arg48-to-Cys Mutation of the Heparin-Binding Domain of Antithrombin  Academic Article
• Ligand interactions at the active site of aspartate transcarbamoylase from Escherichia coli  Academic Article
• Ligands of Diltiazem Binding Site: An Overview of Some Chemotypes  Academic Article
• Like Fibrin, (DD)E, the Major Degradation Product of Crosslinked Fibrin, Protects Plasmin from Inhibition by α2-antiplasmin  Academic Article
• Linear Free Energy Relationship Analysis of Transition State Mimicry by 3-Deoxy-d-arabino-heptulosonate-7-phosphate (DAHP) Oxime, a DAHP Synthase Inhibitor and Phosphate Mimic  Academic Article
• Lipid Trafficking Controls Endotoxin Acylation in Outer Membranes of Escherichia coli  Academic Article
• Localization and characterization of [¹²⁵I]iodomelatonin binding sites in duck gonads  Academic Article
• Localization of the Thrombin-binding Domain on Prothrombin Fragment 2  Academic Article
• Location of the multimerin 1 binding site in coagulation factor V: An update  Academic Article
• Location of two contact sites between human smooth muscle caldesmon and Ca(2+)-calmodulin.  Academic Article
• MCM Proteins Are Associated with RNA Polymerase II Holoenzyme  Academic Article
• Making AppDNA using T4 DNA ligase  Academic Article
• Mapping Allostery through Equilibrium Perturbation NMR Spectroscopy  Academic Article
• Mapping of Steroids Binding to 17β-Hydroxysteroid Dehydrogenase Type 1 Using Monte Carlo Energy Minimization Reveals Alternative Binding Modes  Academic Article
• Mapping the Free Energy Landscape of PKA Inhibition and Activation: A Double-Conformational Selection Model for the Tandem cAMP-Binding Domains of PKA RIα  Academic Article
• Mapping the Interactions between the Alzheimer’s Aβ-Peptide and Human Serum Albumin beyond Domain Resolution  Academic Article
• Mapping the interaction surface of scorpion β-toxins with an insect sodium channel  Academic Article
• Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13  Academic Article
• Mechanism of action of the novel plasma membrane Ca2+-pump inhibitor caloxin  Academic Article
• Mechanism of allosteric inhibition in the Plasmodium falciparum cGMP-dependent protein kinase  Conference Paper
• Mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: role of the nucleotide positioning loop  Academic Article
• Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants  Academic Article
• Mechanisms Responsible for Catalysis of the Inhibition of Factor Xa or Thrombin by Antithrombin Using a Covalent Antithrombin-Heparin Complex  Academic Article
• Mechanisms by Which Soluble Endothelial Cell Protein C Receptor Modulates Protein C and Activated Protein C Function  Academic Article
• Mechanisms of Specific versus Nonspecific Interactions of Aggregation-Prone Inhibitors and Attenuators  Academic Article
• Melatonin receptors in the chicken kidney are up-regulated by pinealectomy and linked to adenylate cyclase  Academic Article
• Melatonin receptors on human granulosa cell membranes.  Academic Article
• Melatonin—A pleiotropic, orchestrating regulator molecule  Academic Article
• Membrane components can modulate the substrate specificity of protein kinase C  Academic Article
• Methods to Validate Binding and Kinetics of “Proximity‐Inducing” Covalent Immune‐Recruiting Molecules  Academic Article
• Microheterogeneity of antithrombin III  Academic Article
• Mineral induction by immobilized phosphoproteins  Academic Article
• Modifications in Perfringolysin O Domain 4 Alter the Cholesterol Concentration Threshold Required for Binding  Academic Article
• Modularity of protein function: Chimeric interleukin 1.beta.s containing specific protease inhibitor loops retain function of both molecules  Academic Article
• Modulating the Activity of Protein Conjugated to Gold Nanoparticles by Site-Directed Orientation and Surface Density of Bound Protein  Academic Article
• Modulation of the Enzymatic Activity of α-Thrombin by Polyanions: Consequences on Intrinsic Activation of Factor V and Factor VIII  Academic Article
• Molecular Basis for the Resistance of Fibrin-Bound Thrombin to Inactivation by Heparin/Serpin Complexes  Academic Article
• Molecular Basis for the Susceptibility of Fibrin-bound Thrombin to Inactivation by Heparin Cofactor II in the Presence of Dermatan Sulfate but Not Heparin  Academic Article
• Molecular Dynamics of Fibrinogen Adsorption onto Graphene, but Not onto Poly(ethylene glycol) Surface, Increases Exposure of Recognition Sites That Trigger Immune Response  Academic Article
• Molecular Mapping of the Thrombin-Heparin Cofactor II Complex  Academic Article
• Molecular Modeling of Benzothiazepine Binding in the L-type Calcium Channel  Academic Article
• Molecular basis of inherited human antithrombin deficiency  Academic Article
• Molecular basis of selective resistance of the bumblebee BiNa _v 1 sodium channel to tau-fluvalinate  Academic Article
• Molecular mechanism of aminoglycoside antibiotic kinase APH(3')-IIIa: roles of conserved active site residues  Academic Article
• Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice  Academic Article
• Monoamine oxidase inhibitor sensitive site implicated in sensitization to quinpirole  Academic Article
• Monoclonal antibodies to Escherichia coli F1-ATPase. Correlation of binding site location with interspecies cross-reactivity and effects on enzyme activity.  Academic Article
• Monte Carlo-energy minimization of correolide in the Kv1.3 channel: possible role of potassium ion in ligand-receptor interactions.  Academic Article
• Mouse NGF promoter upstream sequences do not affect gene expression in mouse fibroblasts  Academic Article
• Multiple [³H]-Oxytocin Binding Sites in Rat Myometrial Plasma Membranes  Academic Article
• Multiple sites and synergism in the binding of inhibitors to microsomal aminopeptidase  Academic Article
• Muscarinic receptor size on smooth muscle cells and membranes  Academic Article
• Mutants of HeLa cells resistant to ouabain and cassaine: Genetic evidence for the common site of action of cardiac glycosides and erythrophleum alkaloids  Academic Article
• Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G  Academic Article
• Myb and Ets related transcription factors are required for activity of the human lck type I promoter.  Academic Article
• NMR assignment of the cAMP-binding domain A of the PKA regulatory subunit  Academic Article
• Natural (dihydro)phenanthrene plant compounds are direct activators of AMPK through its allosteric drug and metabolite–binding site  Academic Article
• Neotrofin, a novel purine that induces NGF-dependent nociceptive nerve sprouting but not hyperalgesia in adult rat skin  Academic Article
• Nerve growth factor inhibitor with novel-binding domain demonstrates nanomolar efficacy in both cell-based and cell-free assay systems  Academic Article
• Neuroimaging of mirtazapine enantiomers in humans  Academic Article
• Nicotinamide adenine dinucleotide depresses synaptic transmission in the hippocampus and has specific binding sites on the synaptic membranes  Academic Article
• Non-sterol structural probes of the lanosterol 14α-demethylase from Saccharomyces cerevisiae  Academic Article
• Noncanonical protein kinase A activation by oligomerization of regulatory subunits as revealed by inherited Carney complex mutations  Academic Article
• Nuclear Import of Cdk/Cyclin Complexes: Identification of Distinct Mechanisms for Import of Cdk2/Cyclin E and Cdc2/Cyclin B1  Academic Article
• Nudeocytoplasmic shuttling by protein nuclear import factors  Academic Article
• Oestradiol decreases rat apolipoprotein AI transcription via promoter site B  Academic Article
• On the interaction of rabbit antithrombin III with the luminal surface of the normal and deendothelialized rabbit thoracic aorta in vitro  Academic Article
• Oncostatin M Stimulates c-Fos to Bind a Transcriptionally Responsive AP-1 Element within the Tissue Inhibitor of Metalloproteinase-1 Promoter  Academic Article
• Ontogeny of 2-[¹²⁵I]iodomelatonin binding sites in the chicken (Gallus domesticus) kidney and spleen  Academic Article
• Overlapping Binding Sites of Structurally Different Antiarrhythmics Flecainide and Propafenone in the Subunit Interface of Potassium Channel Kv2.1*  Academic Article
• PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells  Academic Article
• PagP Crystallized from SDS/Cosolvent Reveals the Route for Phospholipid Access to the Hydrocarbon Ruler  Academic Article
• Paramyxovirus-induced platelet aggregation. Requirement for neuraminic acid receptors on platelets.  Academic Article
• Pervasive Cryptic Epistasis in Molecular Evolution  Academic Article
• Pharmacological characterization of melatonin binding sites in Syrian hamster hypothalamus  Academic Article
• Phenylalkylamines in calcium channels: computational analysis of experimental structures  Academic Article
• Phosphate Analogues as Probes of the Catalytic Mechanisms of MurA and AroA, Two Carboxyvinyl Transferases  Academic Article
• Phosphopeptide Selective Coordination Complexes as Promising Src Homology 2 Domain Mimetics  Academic Article
• Phosphorus-containing inhibitors of aspartate transcarbamoylase fromEscherichia coli  Academic Article
• Phosphorylated Derivatives That Activate or Inhibit Mammalian Adenosine Kinase Provide Insights into the Role of Pentavalent Ions in AK Catalysis  Academic Article
• Photoaffinity labeling of fatty acid-binding proteins involved in long chain fatty acid transport in Escherichia coli.  Academic Article
• Physical Interaction with Human Tumor-derived p53 Mutants Inhibits p63 Activities  Academic Article
• Picomolar-affinity binding and inhibition of adenylate cyclase activity by melatonin in syrian hamster hypothalamus  Academic Article
• PilN Binding Modulates the Structure and Binding Partners of the Pseudomonas aeruginosa Type IVa Pilus Protein PilM  Academic Article
• Platelet IgG Fc receptor  Academic Article
• Platelet imipramine binding is increased in essential thrombocythaemia  Academic Article
• Platelet survival studies. An overview of the factors affecting the efficiency and reliability of platelet radiolabeling  Academic Article
• Polyglutamine domain flexibility mediates the proximity between flanking sequences in huntingtin  Academic Article
• Polyomavirus and simian virus 40 large T antigens bind to common DNA sequences  Academic Article
• Polyomavirus large T antigen binds independently to multiple, unique regions on the viral genome  Academic Article
• Polyomavirus large T-antigen binds the ‘pRb related’ protein p130 through sequences in conserved region 2  Academic Article
• Polyphosphate binds with high affinity to exosite II of thrombin  Academic Article
• Position of residues in transmembrane peptides with respect to the lipid bilayer: a combined lipid Noes and water chemical exchange approach in phospholipid bicelles.  Academic Article
• Potent enantioselective inhibition of DNA-dependent protein kinase (DNA-PK) by atropisomeric chromenone derivatives  Academic Article
• Potentialphilicity and potentialphobicity: Reactivity indicators for external potential changes from density functional reactivity theory  Academic Article
• Predicting the reactivity of ambidentate nucleophiles and electrophiles using a single, general-purpose, reactivity indicator  Academic Article
• Prediction of homoprotein and heteroprotein complexes by protein docking and template‐based modeling: A CASP‐CAPRI experiment  Academic Article
• Predominant Interactions between μ-Conotoxin Arg-13 and the Skeletal Muscle Na⁺ Channel Localized by Mutant Cycle Analysis  Academic Article
• Prejunctional muscarinic receptors in the deep muscular plexus of canine ileum: comparison with smooth muscle receptors.  Academic Article
• Primary structure-based function characterization of BRCT domain replicates in BRCA1  Academic Article
• Probing the "active site" of diamine oxidase: structure-activity relations for histamine potentiation by O-alkylhydroxylamines on colonic epithelium.  Academic Article
• Probing the active site of YjeE: a vital Escherichia coli protein of unknown function  Academic Article
• Production and Characterization of Monoclonal Antibodies to ARVCF  Academic Article
• Protein kinase C: An example of a calcium-regulated protein binding to membranes (Review)  Academic Article
• Pyrazine derivatives affect membrane fluidity of vascular smooth muscle microsomes in relation to their biological activity  Academic Article
• Quality Control Certification of RNA Aptamer-Based Detection  Academic Article
• Quantitative analysis of regions of adenovirus E1A products involved in interactions with cellular proteins  Academic Article
• Quartz crystal microbalance study of protein adsorption kinetics on poly(2-hydroxyethyl methacrylate)  Academic Article
• Rainbow trout exposed to benzo[a]pyrene yields conserved microRNA binding sites in DNA methyltransferases across 500 million years of evolution  Academic Article
• Rapid Evolution of cis-Regulatory Sequences via Local Point Mutations  Academic Article
• Receptor domains of two-component signal transduction systems  Academic Article
• Recognition of Anionic Porphyrins by DNA Aptamers  Academic Article
• Recognition of polyunsaturated acyl chains by enzymes acting on membrane lipids  Academic Article
• Reduction Precedes Cytidylyl Transfer without Substrate Channeling in Distinct Active Sites of the Bifunctional CDP-Ribitol Synthase from Haemophilus influenzae  Academic Article
• Regulation of Smurf2 Ubiquitin Ligase Activity by Anchoring the E2 to the HECT Domain  Academic Article
• Related RNA Polymerase-binding Regions in Human RAP30/74 And Escherichia coli σ70  Academic Article
• Requirement for Both Shc and Phosphatidylinositol 3′ Kinase Signaling Pathways in Polyomavirus Middle T-Mediated Mammary Tumorigenesis  Academic Article
• Requirement of Lysine Residues Outside of the Proposed Pentasaccharide Binding Region for High Affinity Heparin Binding and Activation of Human Antithrombin III  Academic Article
• Rifampin phosphotransferase is an unusual antibiotic resistance kinase  Academic Article
• Role of Half-of-Sites Reactivity and Inter-Subunit Communications in DAHP Synthase Catalysis and Regulation  Academic Article
• Role of dopamine systems in obsessive-compulsive disorder (OCD): implications from a novel psychostimulant-induced animal model.  Academic Article
• Role of mitochondrial calcium transport in failing heart.  Academic Article
• Roles of specific lipid species in the cell and their molecular mechanism  Academic Article
• Rotational Symmetry of Two Pyrethroid Receptor Sites in the Mosquito Sodium Channel  Academic Article
• Ryanodine and the adrenergic, purinergic stimulation in the rat vas deferens smooth muscle: functional and radioligand binding studies.  Academic Article
• Salicylate activates AMPK and synergizes with metformin to reduce the survival of prostate and lung cancer cells ex vivo through inhibition of de novo lipogenesis  Academic Article
• Secondary structure of charge isomers of myelin basic protein before and after phosphorylation  Academic Article
• Selection of a Suppressor Mutation That Restores Affinity of an Oligonucleotide Inhibitor for Thrombin Using in Vitro Genetics  Academic Article
• Selection of novel, specific single-stranded DNA sequences by Flp, a duplex-specific DNA binding protein  Academic Article
• Selective Cu2+ Binding, Redox Silencing, and Cytoprotective Effects of the Small Heat Shock Proteins αA- and αB-Crystallin  Academic Article
• Selective Uncoupling of P120ctn from E-Cadherin Disrupts Strong Adhesion  Academic Article
• Serine-401 as a batrachotoxin- and local anesthetic-sensing residue in the human cardiac Na+ channel  Academic Article
• Silencing cryptic specialized metabolism in Streptomyces by the nucleoid-associated protein Lsr2  Academic Article
• Simultaneous in vitro assay of the first four enzymes in the fungal aspartate pathway identifies a new class of aspartate kinase inhibitor  Academic Article
• Small-Molecule Screening Made Simple for a Difficult Target with a Signaling Nucleic Acid Aptamer that Reports on Deaminase Activity  Academic Article
• Sodium channel activators: Model of binding inside the pore and a possible mechanism of action  Academic Article
• Solution Studies of Isepamicin and Conformational Comparisons between Isepamicin and Butirosin A When Bound to an Aminoglycoside 6‘-N-Acetyltransferase Determined by NMR Spectroscopy  Academic Article
• Somatostatin Binding Sites in Human and Monkey Brain: Localization and Characterization  Academic Article
• Some experimental approaches for studying subunit interactions in enzymes  Academic Article
• Some observations on the affinity chromatography of rabbit plasminogen  Academic Article
• Species Specificity of Amidine-Based Urokinase Inhibitors  Academic Article
• Specific [³H]-guanosine binding sites in rat brain membranes  Academic Article
• Specific labeling of Candida tropicalis peroxisomal proteins with photoreactive fatty-acid derivatives  Academic Article
• Specificity of Membrane Binding of the Neuronal Protein NAP-22  Academic Article
• Spectroscopic evidence of interaction between 2-allyl-2-isopropylacetamide and cytochrome P-450 of rat liver microsomes  Academic Article
• Splicing and transcription-associated proteins PSF and p54nrb/NonO bind to the RNA polymerase II CTD  Academic Article
• Stability and peptide binding specificity of Btk SH2 domain: Molecular basis for X-linked agammaglobulinemia  Academic Article
• Stereospecific binding sites for [3H]nicotinamide adenine dinucleotide in the rat brain  Academic Article
• Stoichiometry and Affinity of the Human Serum Albumin-Alzheimer's Aβ Peptide Interactions  Academic Article
• Streptomyces IHF uses multiple interfaces to bind DNA  Academic Article
• Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I  Academic Article
• Structural Model for Dihydropyridine Binding to L-type Calcium Channels  Academic Article
• Structural Model for Phenylalkylamine Binding to L-type Calcium Channels  Academic Article
• Structural Studies on Cross-Linked Regions of Elastin  Academic Article
• Structural and Binding Effects of Chemical Modifications on Thrombin Binding Aptamer (TBA)  Academic Article
• Structural and Functional Studies of the Pseudomonas aeruginosa Minor Pilin, PilE  Academic Article
• Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor  Academic Article
• Structural basis for a new tetracycline resistance mechanism relying on the TetX monooxygenase  Academic Article
• Structural basis for streptogramin B resistance in Staphylococcus aureus by virginiamycin B lyase  Academic Article
• Structural model of a synthetic Ca2+ channel with bound Ca2+ ions and dihydropyridine ligand  Academic Article
• Structural modeling of calcium binding in the selectivity filter of the L-type calcium channel  Academic Article
• Structural requirements for the activation of human factor VIII by thrombin  Academic Article
• Structure and Functional Relationships in Human pur H  Academic Article
• Structure and function of the N-terminal 40 kDa fragment of human PMS2: a monomeric GHL ATPase  Academic Article
• Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases  Academic Article
• Structure of the Cytoplasmic Region of PelD, a Degenerate Diguanylate Cyclase Receptor That Regulates Exopolysaccharide Production in Pseudomonas aeruginosa  Academic Article
• Structure of the Human 3α-Hydroxysteroid Dehydrogenase Type 3 in Complex with Testosterone and NADP at 1.25-Å Resolution  Academic Article
• Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance  Academic Article
• Studies of membrane physical properties and their role in biological function  Conference Paper
• Studies of the Metabolism of Asialotransferrins: The Mechanism for the Hypercatabolism of Human Asialotransferrin in the Rabbit  Academic Article
• Studies of the metabolism of asialotransferrins: nonspecific changes in the metabolic behaviour of human asialotransferrin in avians  Academic Article
• Studies on Protein Subunits. V. Specific Interaction between Matrix–Bound Subunits of Aldolase and Soluble Aldolase Subunits  Academic Article
• Studies on polynucleotides, LXXXIV. On the role of ribosomal subunits in protein synthesis.  Academic Article
• Study of a series of analogs of salmon calcitonin in which alanine replaces leucine  Academic Article
• Subcellular distribution of dihydropyridine isothiocyanate binding in guinea-pig ileal smooth muscle.  Academic Article
• Subcellular-membrane characterization of [3H]ryanodine-binding sites in smooth muscle  Academic Article
• Substrate Chirality and Specificity of Diacylglycerol Kinases and the Multisubstrate Lipid Kinase  Academic Article
• Subunit interactions in aspartate transcarbamylase from Escherichia coli studied using matrix-bound derivatives  Academic Article
• Subunit interactions in aspartate transcarbamylase. Characterization of a complex between the catalytic and the regulatory subunits  Academic Article
• Synergistic binding of ligands to angiotensin-converting enzyme.  Academic Article
• TATA-binding protein activates transcription when upstream of a GCN4-binding site in a novel yeast promoter.  Academic Article
• Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics  Academic Article
• Targeting of passenger protein domains to multiple intracellular membranes  Academic Article
• Targeting stromal-induced pyruvate kinase M2 nuclear translocation impairs OXPHOS and prostate cancer metastatic spread  Academic Article
• Tenascin-C Splice Variant Adhesive/anti-Adhesive Effects on Chondrosarcoma Cell Attachment to Fibronectin.  Academic Article
• The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase  Academic Article
• The Arginine-Rich Domains Present in Human Immunodeficiency Virus Type 1 Tat and Rev Function as Direct Importin β-Dependent Nuclear Localization Signals  Academic Article
• The Asp272–Glu282 Region of Platelet Glycoprotein Ibα Interacts with the Heparin-binding Site of α-Thrombin and Protects the Enzyme from the Heparin-catalyzed Inhibition by Antithrombin III  Academic Article
• The Binding of Unfractionated Heparin and Low Molecular Weight Heparin to Thrombin-Activated Human Endothelial Cells  Academic Article
• The BldD Protein from Streptomyces coelicolor Is a DNA-Binding Protein  Academic Article
• The C-terminal domain of RNA polymerase II couples mRNA processing to transcription  Academic Article
• The COOH terminus of aminoglycoside phosphotransferase (3')-IIIa is critical for antibiotic recognition and resistance  Academic Article
• The DY genes of the cattle MHC: expression and comparative analysis of an unusual class II MHC gene pair  Academic Article
• The Double-Stranded RNA-Binding Protein Staufen Is Incorporated in Human Immunodeficiency Virus Type 1: Evidence for a Role in Genomic RNA Encapsidation  Academic Article
• The Evolutionary Origins of Eukaryotic Protein Disulfide Isomerase Domains: New Evidence from the Amitochondriate Protist Giardia lamblia  Academic Article
• The Guanylyltransferase Domain of Mammalian mRNA Capping Enzyme Binds to the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II  Academic Article
• The Human Enhancer Blocker CTC-binding Factor Interacts with the Transcription Factor Kaiso  Academic Article
• The Influence of Ser-154, Cys-113, and the Phosphorylated Threonine Residue on the Catalytic Reaction Mechanism of Pin1  Academic Article
• The LysR-type PcaQ protein regulates expression of a protocatechuate-inducible ABC-type transport system in Sinorhizobium meliloti  Academic Article
• The Myxoma Virus-soluble Interferon- γ Receptor Homolog, M-T7, Inhibits Interferon- γ in a Species-specific Manner  Academic Article
• The Orphan Nuclear Hormone Receptor LXRα Interacts with the Peroxisome Proliferator-activated Receptor and Inhibits Peroxisome Proliferator Signaling  Academic Article
• The PEA3 Subfamily of Ets Transcription Factors Synergizes with β-Catenin–LEF-1 To Activate Matrilysin Transcription in Intestinal Tumors  Academic Article
• The Selective Cause of an Ancient Adaptation  Academic Article
• The Sinorhizobium meliloti chromosomal origin of replication  Academic Article
• The Structural Integrity of Anion Binding Exosite I of Thrombin Is Required and Sufficient for Timely Cleavage and Activation of Factor V and Factor VIII  Academic Article
• The Transcriptional Repressor ZEB Regulates p73 Expression at the Crossroad between Proliferation and Differentiation  Academic Article
• The affinity of human, rabbit and bovine thrombins for sepharose-lysine and other conjugates  Academic Article
• The complete N-terminal extension of heparin cofactor II is required for maximal effectiveness as a thrombin exosite 1 ligand  Academic Article
• The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPβ in v-src transformed chicken embryo fibroblasts  Academic Article
• The effects of the trinitrophenylation of the amino groups of glucagon on its conformational properties and on its ability to activate rat liver adenylyl cyclase  Academic Article
• The epsilon subunit and inhibitory monoclonal antibodies interact with the carboxyl-terminal region of the beta subunit of Escherichia coli F1-ATPase.  Academic Article
• The evolution of the class A scavenger receptors  Academic Article
• The interaction of fragment 1 of prothrombin with the membrane surface is a prerequisite for optimum expression of factor Va cofactor activity within prothrombinase  Academic Article
• The membrane bound bacterial lipocalin Blc is a functional dimer with binding preference for lysophospholipids  Academic Article
• The molecular basis of the expansive substrate specificity of the antibiotic resistance enzyme aminoglycoside acetyltransferase-6'-aminoglycoside phosphotransferase-2". The role of ASP-99 as an active site base important for acetyl transfer  Academic Article
• The p120ctn-binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG dinucleotides  Academic Article
• The p56 -interacting Protein p62 Stimulates Transcription via the SV40 Enhancer  Academic Article
• The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults  Academic Article
• The purified myxoma virus gamma interferon receptor homolog M-T7 interacts with the heparin-binding domains of chemokines  Academic Article
• The relevance of the structure of lysine bound to Sepharose for the affinity of rabbit plasminogen  Academic Article
• The role of molybdenum in the synthesis of Neurospora nitrate reductase  Academic Article
• The role of the phospholipid phase transition in the regulation of glucagon binding to lecithin  Academic Article
• The single-stranded DNA aptamer-binding site of human thrombin.  Academic Article
• The solution structure of Lac repressor headpiece 62 complexed to a symmetrical lac operator  Academic Article
• The structure of the apocAMP‐binding domain ofHCN4 – a stepping stone toward understanding thecAMP‐dependent modulation of the hyperpolarization‐activated cyclic‐nucleotide‐gated ion channels  Academic Article
• Theoretical study of interaction of winter flounder antifreeze protein with ice  Academic Article
• Thermodynamic and NMR analysis of inhibitor binding to dihydrofolate reductase  Academic Article
• Three functional classes of transcriptional activation domain  Academic Article
• Thrombin Activation of Factor XI on Activated Platelets Requires the Interaction of Factor XI and Platelet Glycoprotein Ibα with Thrombin Anion-binding Exosites I and II, Respectively  Academic Article
• Thrombin Hydrolysis of Human Osteopontin Is Dependent on Thrombin Anion-binding Exosites  Academic Article
• Thrombin Inhibition by Hirudin: How Hirudin Inhibits Thrombin  Academic Article
• Thrombin Interacts with Thrombomodulin, Protein C, and Thrombin-activatable Fibrinolysis Inhibitor via Specific and Distinct Domains  Academic Article
• Thrombin structure and function  Academic Article
• Toward a Detailed Understanding of Base Excision Repair Enzymes:  Transition State and Mechanistic Analyses of N-Glycoside Hydrolysis and N-Glycoside Transfer  Academic Article
• Toward an Efficient DNAzyme  Academic Article
• Truncation of the C-Terminal Acidic Transcriptional Activation Domain of Herpes Simplex Virus VP16 Renders Expression of the Immediate-Early Genes Almost Entirely Dependent on ICP0  Academic Article
• Two Conserved Histidine Residues Are Critical to the Function of the TagF-like Family of Enzymes  Academic Article
• Tyrosine phosphorylation and cadherin/catenin function  Academic Article
• Ultrasonic and Densimetric Characterization of the Association of Cyclic AMP with the cAMP-Binding Domain of the Exchange Protein EPAC1  Academic Article
• Unfolding of Acrylodan-Labeled Human Serum Albumin Probed by Steady-State and Time-Resolved Fluorescence Methods  Academic Article
• Unraveling Determinants of Affinity Enhancement in Dimeric Aptamers for a Dimeric Protein  Academic Article
• Unraveling the Complexities of DNA-Dependent Protein Kinase Autophosphorylation  Academic Article
• Up-regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain  Academic Article
• Vimentin Exposed on Activated Platelets and Platelet Microparticles Localizes Vitronectin and Plasminogen Activator Inhibitor Complexes on Their Surface  Academic Article
• Zinc promotes clot stability by accelerating clot formation and modifying fibrin structure  Academic Article
• Zn2+ Mediates High Affinity Binding of Heparin to the αC Domain of Fibrinogen  Academic Article
• [10] Archaeal histones and nucleosomes  Book
• [Enhanced translational efficacy of internal ribosomal entry site-mediated mRNA in dendritic cells contributes to efficient induction of antitumor immunity].  Academic Article
• [Molecular physiology of adrenoreceptors].  Academic Article
• [Productive conformations of ligands and topography of the alpha1-adrenoreceptor active site based on theoretical conformation analysis].  Academic Article
• [Theoretical conformational analysis of methylamide N-acetyl-L-arginine].  Academic Article
• [Topography of the active site of the noradrenaline neuronal membrane carrier based on the theoretical conformation analysis of inhibitors of neuronal catecholamine uptake].  Academic Article
• cAMP activation of PKA defines an ancient signaling mechanism  Academic Article
• p53-paralog DNp73 oncogene is repressed by IFNα/STAT2 through the recruitment of the Ezh2 polycomb group transcriptional repressor  Academic Article
• α-Adrenoceptors in Dog Mesenteric Vessels–Subcellular Distribution and Number of [3H]Prazosin and [3H]Rauwolscine Binding Sites  Academic Article