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Streptomyces IHF uses multiple interfaces to bind...
Journal article

Streptomyces IHF uses multiple interfaces to bind DNA

Abstract

BACKGROUND: Nucleoid associated proteins (NAPs) are essential for chromosome condensation in bacterial cells. Despite being a diverse group, NAPs share two common traits: they are small, oligomeric proteins and their oligomeric state is critical for DNA condensation. Streptomyces coelicolor IHF (sIHF) is an actinobacterial-specific nucleoid-associated protein that despite its name, shares neither sequence nor structural homology with the …

Authors

Nanji T; Gehrke EJ; Shen Y; Gloyd M; Zhang X; Firby CD; Huynh A; Razi A; Ortega J; Elliot MA

Journal

Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1863, No. 11,

Publisher

Elsevier

Publication Date

November 2019

DOI

10.1016/j.bbagen.2019.07.014

ISSN

0304-4165