Journal article
Distribution of PK11195 binding sites in porcine brain studied by autoradiography in vitro and by positron emission tomography
Abstract
The cerebral distribution of peripheral-type benzodiazepine binding sites (PBBS) in human brain has been investigated by positron emission tomography (PET) with the specific radioligand [11C]PK11195 in diverse neuropathological conditions. However, little is known about the pattern of PK11195 binding sites in healthy brain. Therefore, we used quantitative autoradiography to measure the saturation binding parameters for [3H]PK11195 in cryostat …
Authors
Cumming P; Pedersen MD; Minuzzi L; Mezzomo K; Danielsen EH; Iversen P; Aagaard D; Keiding S; Munk OL; Finsen B
Journal
Synapse, Vol. 59, No. 7, pp. 418–426
Publisher
Wiley
Publication Date
June 1, 2006
DOI
10.1002/syn.20257
ISSN
0887-4476