Journal article
Rainbow trout exposed to benzo[a]pyrene yields conserved microRNA binding sites in DNA methyltransferases across 500 million years of evolution
Abstract
The objective of this study was to examine the regulation of DNA methylation following acute (24 h) and prolonged (14 d) exposure to low (1 ng/L) and high (10 ng/L) benzo[a]pyrene. However, with the recent release of the rainbow trout genome, we were able to conduct a more detailed analysis regarding the regulation of the enzymes involved in DNA methylation; DNA methyltransferases (DNMTs). Bioinformatic approaches were used to identify …
Authors
Kuc C; Richard DJ; Johnson S; Bragg L; Servos MR; Doxey AC; Craig PM
Journal
Scientific Reports, Vol. 7, No. 1,
Publisher
Springer Nature
DOI
10.1038/s41598-017-17236-x
ISSN
2045-2322