Journal article
High affinity Ca-binding to smooth muscle plasma membrane: Inhibition by cations
Abstract
The effects of Mg2+, Na+ and K+ on the pH-dependent high affinity passive Ca-binding to sarcolemmal enriched membrane fractions from the smooth muscles of rat myometrium and gastric fundus were examined at 1 uM Ca2+-concentration. For the myometrial plasma membranes, these ions inhibited the passive Ca-binding with the following IC50 values: Mg2+: 1.75 mM; Na+: 19 mM; K+: 233 mM. Similarly, for the gastric fundus membranes, the IC50 values were …
Authors
Grover AK; Kwan CY
Journal
Cell Calcium, Vol. 7, No. 3, pp. 187–192
Publisher
Elsevier
Publication Date
June 1986
DOI
10.1016/0143-4160(86)90022-9
ISSN
0143-4160