Journal article
Influence of Particle Size on the Binding Activity of Proteins Adsorbed onto Gold Nanoparticles
Abstract
We used optical extinction spectroscopy to study the structure of proteins adsorbed onto gold nanoparticles of sizes 5-60 nm and their resulting biological binding activity. For these studies, proteins differing in size and shape, with well-characterized and specific interactions-rabbit immunoglobulin G (IgG), goat anti-rabbit IgG (anti-IgG), Staphylococcal protein A, streptavidin, and biotin-were used as model systems. Protein interaction with …
Authors
Kaur K; Forrest JA
Journal
Langmuir, Vol. 28, No. 5, pp. 2736–2744
Publisher
American Chemical Society (ACS)
Publication Date
February 7, 2012
DOI
10.1021/la203528u
ISSN
0743-7463