Antineoplastic Agents Concept

subject area of

• 2 ‐Chloro‐deoxyadenosine therapy for giant lymph node hyperplasia  Journal Articles
• Erwinia asparaginase after allergy to E. coli asparaginase in children with acute lymphoblastic leukemia  Journal Articles
• A Combination of Chemotherapy and Oncolytic Virotherapy Sensitizes Colorectal Adenocarcinoma to Immune Checkpoint Inhibitors in a cDC1-Dependent Manner  Journal Articles
• A Multicenter Phase II Clinical Trial of Lapatinib (GW572016) in Hormonally Untreated Advanced Prostate Cancer  Journal Articles
• A New Strategy To Improve the Metabolic Stability of Lactone: Discovery of (20S,21S)-21-Fluorocamptothecins as Novel, Hydrolytically Stable Topoisomerase I Inhibitors  Journal Articles
• A Phase 1 Study of Mapatumumab (Fully Human Monoclonal Antibody to TRAIL-R1) in Patients with Advanced Solid Malignancies  Journal Articles
• A Phase 2 study of perifosine in advanced or metastatic breast cancer  Journal Articles
• A Phase I Study of OGX-011, a 2′-Methoxyethyl Phosphorothioate Antisense to Clusterin, in Combination with Docetaxel in Patients with Advanced Cancer  Journal Articles
• A Phase I Study of the combination of oxaliplatin/docetaxel and vandetanib for the treatment of advanced gastroesophageal cancer  Journal Articles
• A Phase II Multicentre, Open-Label, Proof-of-Concept Study of Tasquinimod in Hepatocellular, Ovarian, Renal Cell, and Gastric Cancers  Journal Articles
• A Phase II Trial with Pharmacodynamic Endpoints of the Proteasome Inhibitor Bortezomib in Patients with Metastatic Colorectal Cancer  Journal Articles
• A Pilot Study of Hypofractionated Stereotactic Radiation Therapy and Sunitinib in Previously Irradiated Patients With Recurrent High-Grade Glioma  Journal Articles
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Journal Articles
• A Suggested Prognostic Reclassification of Intermediate and Poor-Risk Nonseminomatous Germ Cell Tumors  Journal Articles
• A comparison of patient adherence and preference of packaging method for oral anticancer agents using conventional pill bottles versus daily pill boxes  Journal Articles
• A formulary for pediatric oncology in developing countries  Journal Articles
• A four gene signature of chromosome instability (CIN4) predicts for benefit from taxanes in the NCIC-CTG MA21 clinical trial  Journal Articles
• A mechanistic cohort study evaluating cognitive impairment in women treated for breast cancer  Journal Articles
• A multi-method review of home-based chemotherapy  Journal Articles
• A multicenter pilot‐randomized controlled trial of the feasibility of an augmented red blood cell transfusion strategy for patients treated with induction chemotherapy for acute leukemia or stem cell transplantation  Journal Articles
• A multicentric phase II clinical trial on intra-arterial hepatic radiotherapy with 90yttrium SIR-spheres in unresectable, colorectal liver metastases refractory to i.v. chemotherapy: preliminary results on toxicity and response rates.  Journal Articles
• A new frontier in treatment of advanced melanoma: Redefining clinical management in the era of immune checkpoint inhibitors  Journal Articles
• A new tool to assess bleeding severity in patients with chemotherapy‐induced thrombocytopenia (CME)  Journal Articles
• A novel stem cell culture model of recurrent glioblastoma  Journal Articles
• A novel synthetic C-1 analogue of 7-deoxypancratistatin induces apoptosis in p53 positive and negative human colorectal cancer cells by targeting the mitochondria: enhancement of activity by tamoxifen  Journal Articles
• A pharmacodynamic study of the epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 in metastatic colorectal cancer patients.  Journal Articles
• A phase 1 study of OSI-211 given as an intravenous infusion days 1, 2, and 3 every three weeks in patients with solid cancers  Journal Articles
• A phase 2 study of cediranib in recurrent or persistent ovarian, peritoneal or fallopian tube cancer: A trial of the Princess Margaret, Chicago and California Phase II Consortia  Journal Articles
• A phase 2 study of patupilone in patients with metastatic castration-resistant prostate cancer previously treated with docetaxel: Canadian Urologic Oncology Group study P07a  Conferences
• A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours  Journal Articles
• A phase I study of oral ZD 1839 given daily in patients with solid tumors: IND.122, a study of the Investigational New Drug Program of the National Cancer Institute of Canada Clinical Trials Group  Journal Articles
• A phase II and pharmacokinetic study of SB-715992, in patients with metastatic hepatocellular carcinoma: a study of the National Cancer Institute of Canada Clinical Trials Group (NCIC CTG IND.168)  Journal Articles
• A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas  Conferences
• A phase II study of PS-341 (Bortezomib) in advanced or metastatic urothelial cancer. A trial of the Princess Margaret Hospital and University of Chicago phase II consortia  Journal Articles
• A phase II study of SB939, a novel pan-histone deacetylase inhibitor, in patients with translocation-associated recurrent/metastatic sarcomas—NCIC-CTG IND 200  Journal Articles
• A phase II study of bortezomib in mantle cell lymphoma: the National Cancer Institute of Canada Clinical Trials Group trial IND.150  Journal Articles
• A phase II study of cediranib (AZD 2171) in treatment naive patients with progressive unresectable recurrent or metastatic renal cell carcinoma. A trial of the PMH phase 2 consortium  Journal Articles
• A phase II study of ispinesib (SB-715992) in patients with metastatic or recurrent malignant melanoma: a National Cancer Institute of Canada Clinical Trials Group trial  Journal Articles
• A phase II study of oral clofazimine in unresectable and metastatic hepatocellular carcinoma  Journal Articles
• A phase II study of perifosine (D-21226) in patients with previously untreated metastatic or locally advanced soft tissue sarcoma: A National Cancer Institute of Canada Clinical Trials Group trial  Journal Articles
• A phase II study of sorafenib in advanced uterine carcinoma/carcinosarcoma: A trial of the Chicago, PMH, and California Phase II Consortia  Journal Articles
• A phase II study of sorafenib in combination with bicalutamide in patients with chemotherapy-naive castration resistant prostate cancer  Journal Articles
• A phase II study of sorafenib in patients with chemo-naive castration-resistant prostate cancer  Journal Articles
• A phase II study of sunitinib in patients with recurrent epithelial ovarian and primary peritoneal carcinoma: an NCIC Clinical Trials Group Study  Journal Articles
• A phase II study of the halichondrin B analog eribulin mesylate in gemcitabine refractory advanced pancreatic cancer  Journal Articles
• A phase II study single agent of aflibercept (VEGF Trap) in patients with recurrent or metastatic gynecologic carcinosarcomas and uterine leiomyosarcoma. A trial of the Princess Margaret Hospital, Chicago and California Cancer Phase II Consortia  Journal Articles
• A phase II trial of ZD1839 (Iressa™) 750 mg per day, an oral epidermal growth factor receptor-tyrosine kinase inhibitor, in patients with metastatic colorectal cancer  Journal Articles
• A phase II trial of dacomitinib, an oral pan-human EGF receptor (HER) inhibitor, as first-line treatment in recurrent and/or metastatic squamous-cell carcinoma of the head and neck  Conferences
• A phase II trial of dovitinib in previously-treated advanced pleural mesothelioma: The Ontario Clinical Oncology Group  Journal Articles
• A phase II trial of sorafenib in first-line metastatic urothelial cancer: a study of the PMH Phase II Consortium  Journal Articles
• A phase II trial of sunitinib in women with metastatic or recurrent endometrial carcinoma: A study of the Princess Margaret, Chicago and California Consortia  Journal Articles
• A phase Ib combination study of RO4929097, a gamma-secretase inhibitor, and temsirolimus in patients with advanced solid tumors  Journal Articles
• A polymer-based drug delivery system for the antineoplastic agent bis(maltolato)oxovanadium in mice  Journal Articles
• A qualitative study evaluating causality attribution for serious adverse events during early phase oncology clinical trials  Journal Articles
• A quantitative systems approach to identify paracrine mechanisms that locally suppress immune response to Interleukin-12 in the B16 melanoma model  Journal Articles
• A randomized controlled trial comparing standard- and low-dose strategies for transfusion of platelets (SToP) to patients with thrombocytopenia  Journal Articles
• A randomized phase II efficacy and safety study of vandetanib (ZD6474) in combination with bicalutamide versus bicalutamide alone in patients with chemotherapy naïve castration-resistant prostate cancer  Journal Articles
• A randomized phase II trial of apixaban for the prevention of thromboembolism in patients with metastatic cancer  Journal Articles
• A randomized placebo-controlled study of tamoxifen after adjuvant chemotherapy in premenopausal women with early breast cancer (National Cancer Institute of Canada—Clinical Trials Group Trial, MA.12)  Journal Articles
• A randomized, double-blind, window of opportunity trial evaluating the effects of chloroquine in breast cancer patients  Journal Articles
• A randomized, double-blinded study comparing six doses of batanopride (BMY-25801) with methylprednisolone in patients receiving moderately emetogenic chemotherapy  Journal Articles
• A set of NF-κB–regulated microRNAs induces acquired TRAIL resistance in Lung cancer  Journal Articles
• A single-institution experience of salvage therapy for patients with early and locally advanced breast cancer who progress during neoadjuvant chemotherapy  Journal Articles
• A synthesis of 3-deoxydihydrolycoricidine: Refinement of a structurally minimum pancratistatin pharmacophore  Journal Articles
• A systematic review of patient values, preferences and expectations for the treatment of recurrent ovarian cancer  Journal Articles
• A target based approach identifies genomic predictors of breast cancer patient response to chemotherapy  Journal Articles
• ABT-510 induces tumor cell apoptosis and inhibits ovarian tumor growth in an orthotopic, syngeneic model of epithelial ovarian cancer  Journal Articles
• AMP-activated protein kinase (AMPK) beyond metabolism  Journal Articles
• Aberrant Epigenetic Regulation: A Central Contributor to Lung Carcinogenesis and a New Therapeutic Target  Journal Articles
• Aberrations in Plasma Phospholipid Fatty Acids in Lung Cancer Patients  Journal Articles
• Ability of C‐reactive protein to complement multiple prognostic classifiers in men with metastatic castration resistant prostate cancer receiving docetaxel‐based chemotherapy  Journal Articles
• Access to Cytotoxic Medicines by Children With Cancer: A Focus on Low and Middle Income Countries  Journal Articles
• Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement  Journal Articles
• Access to essential medicines for children with cancer: a joint SIOP-CCI position statement  Journal Articles
• Activation of host antitumoral responses by cationic lipid/DNA complexes  Journal Articles
• Activity of venetoclax in patients with relapsed or refractory chronic lymphocytic leukaemia: analysis of the VENICE-1 multicentre, open-label, single-arm, phase 3b trial  Journal Articles
• Acupuncture Treatment for Chemotherapy-Induced Peripheral Neuropathy – a Case Series  Journal Articles
• Addressing Taxane Resistance in Metastatic Castration-Resistant Prostate Cancer: A Focus On Chaperone Proteins  Journal Articles
• Addressing adherence to guidelines on prevention of acute chemotherapy‐induced nausea and vomiting in pediatric patients  Conferences
• Addressing the affordability of cancer drugs: using deliberative public engagement to inform health policy  Journal Articles
• Adjunctive therapy (whole body hyperthermia versus lonidamine) to total body irradiation for the treatment of favorable b-cell neoplasms: a report of two pilot clinical trials and laboratory investigations  Journal Articles
• Adjuvant Therapy for Breast Cancer  Journal Articles
• Adjuvant chemotherapy for completely resected non-small cell lung cancer: A systematic review  Journal Articles
• Adjuvant chemotherapy for localised resectable soft tissue sarcoma in adults  Journal Articles
• Adjuvant chemotherapy for upper-tract urothelial carcinoma treated with nephroureterectomy: Assessment of adequate renal function and influence on outcome  Journal Articles
• Adjuvant chemotherapy in colorectal carcinoma  Conferences
• Adjuvant radiation therapy, androgen deprivation, and docetaxel for high‐risk prostate cancer postprostatectomy: Results of NRG Oncology/RTOG study 0621  Journal Articles
• Adjuvant sunitinib following chemoradiotherapy and surgery for locally advanced esophageal cancer: a phase II trial  Journal Articles
• Adjuvant therapy and thrombosis: How to avoid the problem?  Journal Articles
• Advances in Cancer Therapeutics and Patient Access to New Drugs  Journal Articles
• Advancing Novel Molecular Imaging Agents from Preclinical Studies to First-in-Humans Phase I Clinical Trials in Academia—A Roadmap for Overcoming Perceived Barriers  Journal Articles
• Akt isoform specific effects in ovarian cancer progression  Journal Articles
• Alemtuzumab and CHOP Chemotherapy for the Treatment of Aggressive Histology Peripheral T Cell Lymphomas: A Multi-Center Phase I Study  Journal Articles
• An Endogenous Reactive Oxygen Species (ROS)‐Activated Histone Deacetylase Inhibitor Prodrug for Cancer Chemotherapy  Journal Articles
• An Increase in Cellular Size Variance Contributes to the Increase in Ultrasound Backscatter During Cell Death  Journal Articles
• An international expanded-access programme of everolimus: Addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy  Journal Articles
• Angiosarcomas--clinical profile, pathology and management.  Journal Articles
• Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels  Journal Articles
• Antagonists of the serotonin receptor 5A target human breast tumor initiating cells  Journal Articles
• Antibiotic and Antimalarial Quinones from Fungus-Growing Ant-Associated Pseudonocardia sp.  Journal Articles
• Antimitotic and cell growth inhibitory properties of combretastatin A-4-like ethers  Journal Articles
• Antineoplastic Agents 491.¹ Synthetic Conversion of Aaptamine to Isoaaptamine, 9-Demethylaaptamine, and 4-Methylaaptamine  Journal Articles
• Antineoplastic Agents. 362. Isolation and X-ray Crystal Structure of Dibromophakellstatin from the Indian Ocean Sponge Phakellia mauritiana  Journal Articles
• Antineoplastic Agents. 380. Isolation and X-ray Crystal Structure Determination of Isoaaptamine from the Republic of Singapore Hymeniacidon sp. and Conversion to the Phosphate Prodrug Hystatin 1  Journal Articles
• Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies.  Journal Articles
• Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression  Journal Articles
• Apixaban to Prevent Venous Thromboembolism in Patients with Cancer  Journal Articles
• Application of the systematic review and bibliometric network analysis (SeBriNA) methodology contextualizes evidence. Part 2: rituximab for non-Hodgkin's lymphoma  Journal Articles
• Approach to evaluation of fever in ambulatory cancer patients receiving chemotherapy: A systematic review  Journal Articles
• Arachidonic acid drives adaptive responses to chemotherapy-induced stress in malignant mesothelioma  Journal Articles
• Are health states ‘timeless’? A case study of an acute condition: post‐chemotherapy nausea and vomiting¹  Conferences
• Are heparins anti-neoplastic agents?  Journal Articles
• Arterial occlusion in patients with peripheral vascular disease treated with platinum-based regimens for lung cancer  Journal Articles
• Assessment of Alectinib vs Ceritinib in ALK-Positive Non–Small Cell Lung Cancer in Phase 2 Trials and in Real-world Data  Journal Articles
• Association Between RECIST Changes and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Receiving Docetaxel  Journal Articles
• Association between progression-free survival and health-related quality of life in oncology: a systematic review protocol  Journal Articles
• Association of Supporting Trial Evidence and Reimbursement for Off-Label Use of Cancer Drugs  Journal Articles
• Association of Urine Platinum With Acute Kidney Injury in Children Treated With Cisplatin for Cancer  Journal Articles
• Assumptions of Expected Benefits in Randomized Phase III Trials Evaluating Systemic Treatments for Cancer  Journal Articles
• Atropine and Roscovitine Release from Model Silicone Hydrogels  Journal Articles
• Atypical Lone Pair–π Interaction with Quinone Methides in a Series of Imido‐Ferrociphenol Anticancer Drug Candidates  Journal Articles
• Atypical McMurry Cross-Coupling Reactions Leading to a New Series of Potent Antiproliferative Compounds Bearing the Key [Ferrocenyl-Ene-Phenol] Motif  Journal Articles
• Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor  Journal Articles
• Autologous and Allogeneic Stem-Cell Transplantation for Transformed Follicular Lymphoma: A Report of the Canadian Blood and Marrow Transplant Group  Journal Articles
• BAY 43-9006: Early Clinical Data in Patients with Advanced Solid Malignancies  Journal Articles
• BCL2L1 is associated with γ-globin gene expression  Journal Articles
• BDNF and PDE4, but not the GRPR, Regulate Viability of Human Medulloblastoma Cells  Journal Articles
• Bench-to-bedside research and the human tumor stem-cell assay--bridging the credibility gap.  Journal Articles
• Benefit From Exemestane As Extended Adjuvant Therapy After 5 Years of Adjuvant Tamoxifen: Intention-to-Treat Analysis of the National Surgical Adjuvant Breast and Bowel Project B-33 Trial  Journal Articles
• Benzodiazepine-induced inhibition of human malignant melanoma (M-6) cell growth.  Journal Articles
• Better Treatments That Cost More: The Dilemma  Journal Articles
• Biased Evaluation in Cancer Drug Trials—How Use of Progression-Free Survival as the Primary End Point Can Mislead  Journal Articles
• Bim escapes displacement by BH3-mimetic anti-cancer drugs by double-bolt locking both Bcl-XL and Bcl-2  Journal Articles
• Biochip arrays for the discovery of a biomarker surrogate in a phase I/II study assessing a novel anti-metastasis agent  Journal Articles
• Blood lipid profiles in children with acute lymphoblastic leukemia  Journal Articles
• Body Composition as an Independent Determinant of 5-Fluorouracil–Based Chemotherapy Toxicity  Journal Articles
• Body composition in long‐term survivors of acute lymphoblastic leukemia diagnosed in childhood and adolescence: A focus on sarcopenic obesity  Journal Articles
• Body composition in patients with non−small cell lung cancer: a contemporary view of cancer cachexia with the use of computed tomography image analysis  Journal Articles
• Bone Health and Bone-targeted Therapies for Prostate Cancer: a Programme in Evidence-based Care — Cancer Care Ontario Clinical Practice Guideline  Journal Articles
• Bone Metastases as the Only Metastatic Site in Patients With Urothelial Carcinoma: Focus on a Special Patient Population  Journal Articles
• Bone Turnover Markers as Predictors of Skeletal Complications in Prostate Cancer, Lung Cancer, and Other Solid Tumors  Journal Articles
• Bone and mineral abnormalities in childhood acute lymphoblastic leukemia: Influence of disease, drugs and nutrition  Journal Articles
• Bortezomib in Multiple Myeloma: A Practice Guideline  Journal Articles
• Bortezomib in Relapsed or Refractory Waldenström's Macroglobulinemia  Journal Articles
• Breast cancer chemotherapy induces the release of cell‐free DNA, a novel procoagulant stimulus  Journal Articles
• Brief Report: A Phase II Study of Sunitinib in Malignant Pleural Mesothelioma. The NCIC Clinical Trials Group  Journal Articles
• Building a National Reassessment Process for Oncology Drugs: Lessons Learned by the Canadian Real-World Evidence for Value of Cancer Drugs (CanREValue) Collaboration through a Simulated Reassessment Exercise  Journal Articles
• Butein impairs the protumorigenic activity of malignant pleural mesothelioma cells  Journal Articles
• CNS Prophylaxis and Treatment in Non-Hodgkin's Lymphoma: Variation in Practice and Lessons from the Literature  Journal Articles
• CT assessment of tumour response to treatment: comparison of linear, cross-sectional and volumetric measures of tumour size.  Journal Articles
• Cabozantinib for Progressive Metastatic Castration-resistant Prostate Cancer Following Docetaxel: Combined Analysis of Two Phase 3 Trials  Journal Articles
• Campath-1H Treatment of T-Cell Prolymphocytic Leukemia in Patients for Whom at Least One Prior Chemotherapy Regimen Has Failed  Journal Articles
• Canadian Cancer Trials Group IND197: a phase II study of foretinib in patients with estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2-negative recurrent or metastatic breast cancer  Journal Articles
• Canadian Perspectives: Update on Inhibition of ALK-Positive Tumours in Advanced Non-Small-Cell Lung Cancer  Journal Articles
• Canadian consensus statement on the management of radioactive iodine–resistant differentiated thyroid cancer  Journal Articles
• Cancer Care Ontario's New Drug Funding Program: controlled introduction of expensive anticancer drugs.  Journal Articles
• Cancer Cell Mitochondria Targeting by Pancratistatin Analogs is Dependent on Functional Complex II and III  Journal Articles
• Cancer and Tumor-Associated Childhood Stroke: Results From the International Pediatric Stroke Study  Journal Articles
• Cancer-Induced Oxidative Stress and Pain  Journal Articles
• Cancer-associated bone disease  Journal Articles
• Cardiac Outcomes in Pregnant Women With Treated Cancer  Journal Articles
• Cardiovascular Risk in Men with Prostate Cancer: Insights from the RADICAL PC Study  Journal Articles
• Cardiovascular events in chronic myeloid leukemia clinical trials. Is it time to reassess and report the events according to cardiology guidelines?  Journal Articles
• Cardiovascular toxicities of BCR-ABL tyrosine kinase inhibitors in chronic myeloid leukemia: preventive strategies and cardiovascular surveillance  Journal Articles
• Carryover and the Two-Period Crossover Clinical Trial  Journal Articles
• Catheter-Associated Thrombosis: Thromboprophylaxis or Not?  Journal Articles
• Causes of reversible nephrogenic diabetes insipidus: A systematic review  Journal Articles
• Cell Permeating Nano-Complexes of Amphiphilic Polyelectrolytes Enhance Solubility, Stability, and Anti-Cancer Efficacy of Curcumin  Journal Articles
• Cervical cancer in the older woman  Journal Articles
• Cetuximab in Metastatic Squamous Cell Cancer of the Skin: A Swiss Case Series  Journal Articles
• Changes in Liver Volume Observed Following Sorafenib and Liver Radiation Therapy  Journal Articles
• Changes in mitochondrial mass, membrane potential, and cellular adenosine triphosphate content during the cell cycle of human leukemic (HL-60) cells  Journal Articles
• Changes in plasma hormones and heart rate variability in patients receiving the cardiotoxic anti-cancer agent bevacizumab  Journal Articles
• Characterisation of the lung toxicity of the cell cycle inhibitor temsirolimus  Journal Articles
• Characteristics and interpretation of subgroup analyses based on tumour characteristics in randomised trials testing target-specific anticancer drugs: design of a systematic survey  Journal Articles
• Characterization of Mutational Status, Spheroid Formation, and Drug Response of a New Genomically-Stable Human Ovarian Clear Cell Carcinoma Cell Line, 105C  Journal Articles
• Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain  Journal Articles
• Chemotherapy agents and the induction of late lethal defects.  Journal Articles
• Chemotherapy enhances endothelial cell reactivity to platelets  Journal Articles
• Chemotherapy for metastatic transitional carcinoma of the urinary tract:A prospective trial of methotrexate, adriamycin, and cyclophosphamide (MAC) with cis-platinum for failure  Journal Articles
• Chemotherapy for recurrent epithelial ovarian cancer previously treated with platinum--a systematic review of the evidence from randomized trials.  Journal Articles
• Chemotherapy of advanced ovarian carcinoma: Initial experience using a platinum-based combination  Journal Articles
• Chemotherapy-Induced Neuropathy and Drug Discovery Platform Using Human Sensory Neurons Converted Directly from Adult Peripheral Blood  Journal Articles
• Children Receiving Chemotherapy at Home: Perceptions of Children and Parents  Journal Articles
• Children who receive antineoplastic treatment may be more likely to develop dental defects  Journal Articles
• Cisplatin-Based First-Line Therapy for Advanced Urothelial Carcinoma After Previous Perioperative Cisplatin-Based Therapy  Journal Articles
• Classification of the acute emetogenicity of chemotherapy in pediatric patients: A clinical practice guideline  Journal Articles
• Clinical Outcomes and Adverse Events after First-Line Treatment in Metastatic Renal Cell Carcinoma: A Systematic Review and Network Meta-Analysis  Journal Articles
• Clinical Practice Guidelines in Cardio-Oncology  Journal Articles
• Clinical Trial Evidence Supporting US Food and Drug Administration Approval of Novel Cancer Therapies Between 2000 and 2016  Journal Articles
• Clinical and Molecular Studies of the Effect of Imatinib on Advanced Aggressive Fibromatosis (desmoid tumor)  Journal Articles
• Clinical and toxicity predictors of response and progression to temsirolimus in women with recurrent or metastatic endometrial cancer  Journal Articles
• Clinical benefit of glasdegib plus low-dose cytarabine in patients with de novo and secondary acute myeloid leukemia: long-term analysis of a phase II randomized trial  Journal Articles
• Clinical outcome following post‐chemotherapy retroperitoneal lymph node dissection in men with intermediate‐ and poor‐risk nonseminomatous germ cell tumour  Journal Articles
• Clinical practice guideline-inconsistent chemotherapy-induced vomiting prophylaxis in pediatric cancer patients in community settings: A Children's Oncology Group study.  Journal Articles
• Clinical practice guidelines for the care and treatment of breast cancer: adjuvant systemic therapy for node-positive breast cancer (summary of the 2001 update). The Steering Committee on Clinical Practice Guidelines for the Care and Treatment of Breast Cancer.  Journal Articles
• Clinical practice guidelines for the care and treatment of breast cancer: follow-up after treatment for breast cancer (summary of the 2005 update)  Journal Articles
• Clinical trial design in metastatic breast cancer: a commentary.  Journal Articles
• Combination chemotherapy in invasive thymoma role of COPP.  Journal Articles
• Combined Modality Treatment of Small Cell Carcinoma of the Lung  Journal Articles
• Combined gamma‐irradiation and subsequent cisplatin treatment in human squamous carcinoma cell lines sensitive and resistant to cisplatin  Journal Articles
• Combined therapy with thrombospondin‐1 type I repeats (3TSR) and chemotherapy induces regression and significandy improves survival in a preclinical model of advanced stage epithelial ovarian cancer  Journal Articles
• Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy  Journal Articles
• Comparative safety and effectiveness of serotonin receptor antagonists in patients undergoing chemotherapy: a systematic review and network meta-analysis  Journal Articles
• Comparison of the mutagenic responses of 12 anticancer drugs at the hypoxanthine‐guanine phosphoribosyl transferase and adenosine kinase loci in chinese hamster ovary cells  Journal Articles
• Comparison of three assays for genetic effects of antineoplastic drugs on cancer patients and their nurses  Journal Articles
• Compound Kushen Injection suppresses human breast cancer stem-like cells by down-regulating the canonical Wnt/β-catenin pathway  Journal Articles
• Conference abstracts of a new oncology drug do not always lead to full publication: Proceed with caution  Journal Articles
• Continental Divide? The Attitudes of US and Canadian Oncologists on the Costs, Cost-Effectiveness, and Health Policies Associated With New Cancer Drugs  Journal Articles
• Contrasting evidence to reimbursement reality for off-label use (OLU) of drug treatments in cancer care: rationale and design of the CEIT-OLU project  Journal Articles
• Cost Effectiveness of EML4-ALK Fusion Testing and First-Line Crizotinib Treatment for Patients With Advanced ALK-Positive Non–Small-Cell Lung Cancer  Journal Articles
• Cost effectiveness of outpatient treatment for febrile neutropaenia in adult cancer patients  Journal Articles
• Cost-Effectiveness of Osimertinib in Treating Newly Diagnosed, Advanced EGFR-Mutation-Positive Non-Small Cell Lung Cancer  Journal Articles
• Cost-effectiveness of Osimertinib as a Second-line Treatment in Patients With EGFR-mutated Advanced Non–Small Cell Lung Cancer in China  Journal Articles
• Cost-utility of nelarabine for the first-line treatment of newly diagnosed pediatric T-cell acute lymphoblastic leukemia in Canada.  Conferences
• Costs of Treating and Preventing Nausea and Vomiting in Patients Receiving Chemotherapy  Journal Articles
• Cross resistance pattern towards anticancer drugs of a human carcinoma multidrug-resistant cell line  Journal Articles
• Current Incidence and Outcomes of Gastrointestinal Mesenchymal Tumors Including Gastrointestinal Stromal Tumors  Journal Articles
• Current Issues in Cancer Management of carcinomas of the upper gastrointestinal tract  Journal Articles
• Cysteine-Rich Protein Reverses Weight Loss in Lung Cancer Patients Receiving Chemotherapy or Radiotherapy  Journal Articles
• Cytokines oncostatin M and interleukin 1 regulate the expression of the IL-6 receptor (gp80, gp130)  Journal Articles
• DIFFERENTIAL SENSITIVITY TO SHORT-CHAIN CERAMIDE ANALOGUES OF HUMAN INTESTINAL CARCINOMA CELLS GROWN IN TUMOR SPHEROIDS VERSUS MONOLAYER CULTURE  Journal Articles
• Daratumumab in newly diagnosed MM — incorporating lessons learnt from CASSIOPEIA, MAIA and beyond  Journal Articles
• De novo necroptosis creates an inflammatory environment mediating tumor susceptibility to immune checkpoint inhibitors  Journal Articles
• De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017  Journal Articles
• Deciphering the Diversified Metabolic Behavior of Hydroxyalkyl Ferrocidiphenols as Anticancer Complexes  Journal Articles
• Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non‐surgical patients  Journal Articles
• Deptor transcriptionally regulates endoplasmic reticulum homeostasis in multiple myeloma cells  Journal Articles
• Design Considerations in Crossover Trials with a Single Interim Analysis and Serial Patient Entry  Journal Articles
• Design, synthesis and biological activity of piperlongumine derivatives as selective anticancer agents  Journal Articles
• Design, synthesis and biological evaluation of di-substituted noscapine analogs as potent and microtubule-targeted anticancer agents  Journal Articles
• Detection and monitoring of cardiotoxicity—what does modern cardiology offer?  Conferences
• Determining optimal sample sizes for multi-stage randomized clinical trials using value of information methods  Journal Articles
• Developing a framework to incorporate real-world evidence in cancer drug funding decisions: the Canadian Real-world Evidence for Value of Cancer Drugs (CanREValue) collaboration  Journal Articles
• Development of adapted RECIST criteria to assess response in lymphoma and their comparison to the International Workshop Criteria  Journal Articles
• Developments in cancer prevention and treatment using traditional Chinese medicine  Journal Articles
• Dexamethasone dosing for prevention of acute chemotherapy‐induced vomiting in pediatric patients: A systematic review  Journal Articles
• Dexamethasone improves the efficacy of granisetron in the first 24 h following high-dose cisplatin chemotherapy  Journal Articles
• Diabetes and breast cancer among women with BRCA1 and BRCA2 mutations  Journal Articles
• Diagnostic and therapeutic approaches for nonmetastatic breast cancer in Canada, and their associated costs  Journal Articles
• Direct anti‐cancer effect of oncostatin M on chondrosarcoma  Journal Articles
• Discovery of 1-arylpyrrolidone derivatives as potent p53–MDM2 inhibitors based on molecule fusing strategy  Journal Articles
• Discovery of HDAC6-Selective Inhibitor NN-390 with in Vitro Efficacy in Group 3 Medulloblastoma  Journal Articles
• Discovery of a novel class of aldol-derived 1,2,3-triazoles: Potent and selective inhibitors of human cytochrome P450 19A1 (aromatase)  Journal Articles
• Distribution of the anticancer drugs doxorubicin, mitoxantrone and topotecan in tumors and normal tissues  Journal Articles
• Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells  Journal Articles
• Domains of Structured Oral Anticancer Medication Programs: A Scoping Review  Journal Articles
• Double-blind randomised trial of very-low-dose warfarin for prevention of thromboembolism in stage IV breast cancer  Journal Articles
• Doxorubicin administration by continuous infusion is not cardioprotective: the Dana-Farber 91-01 Acute Lymphoblastic Leukemia protocol.  Journal Articles
• Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer.  Journal Articles
• Drug-induced peripheral neuropathies.  Journal Articles
• Drugs targeting Bcl-2 family members as an emerging strategy in cancer  Journal Articles
• Durable remission of both multicentric Castleman's disease and Kaposi's sarcoma with valganciclovir, rituximab and liposomal doxorubicin in an HHV-8-positive, HIV-negative patient  Journal Articles
• Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Vascular Changes Induced by Sunitinib in Papillary Renal Cell Carcinoma Xenograft Tumors  Journal Articles
• EPIDERMAL GROWTH FACTOR-MEDIATED ACTIVATION OF THE MAP KINASE CASCADE RESULTS IN ALTERED EXPRESSION AND FUNCTION OF ABCG2 (BCRP)  Journal Articles
• Early tumor shrinkage is independently associated with improved overall survival among patients with metastatic renal cell carcinoma: a validation study using the COMPARZ cohort  Journal Articles
• Early‐stage Hodgkin lymphoma in the modern era: simulation modelling to delineate long‐term patient outcomes  Journal Articles
• Economic evaluation of nivolumab for the treatment of second-line advanced squamous NSCLC in Canada: a comparison of modeling approaches to estimate and extrapolate survival outcomes  Journal Articles
• Editorial Comment on: Metastin Inhibits Migration and Invasion of Renal Cell Carcinoma with Overexpression of Metastin Receptor  Journal Articles
• Educational Paper: Decreasing the burden of cardiovascular disease in childhood cancer survivors: An update for the pediatrician  Journal Articles
• Effect of Herceptin on the development and progression of skeletal metastases in a xenograft model of human breast cancer  Journal Articles
• Effect of Letrozole Versus Placebo on Bone Mineral Density in Women With Primary Breast Cancer Completing 5 or More Years of Adjuvant Tamoxifen: A Companion Study to NCIC CTG MA.17  Journal Articles
• Effect of Metformin vs Placebo on Invasive Disease–Free Survival in Patients With Breast Cancer  Journal Articles
• Effect of aerobic exercise on cancer‐associated cognitive impairment: A proof‐of‐concept RCT  Journal Articles
• Effect of radiation and other cytotoxic agents on the growth of cells cultured from normal and tumor tissues from the female genital tract  Journal Articles
• Effects of Antimicrobial and Antineoplastic Drugs on the Phagocytic and Microbicidal Function of the Polymorphonuclear Leukocyte  Journal Articles
• Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus (VSV ΔM51 ) on Multifocal and Invasive Gliomas  Journal Articles
• Effects of Sweet Bee Venom Pharmacopuncture Treatment for Chemotherapy-Induced Peripheral Neuropathy  Journal Articles
• Effects of antimitotic and antimitochondrial agents on the cellular distribution of microtubules and mitochondria.  Journal Articles
• Effects of metformin versus placebo on vitamin B12 metabolism in non-diabetic breast cancer patients in CCTG MA.32  Journal Articles
• Efficacy and Safety of Gemcitabine Plus Either Taxane or Carboplatin in the First-Line Setting of Metastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis  Journal Articles
• Efficacy, Toxicity, and Quality of Life in Older Women With Early-Stage Breast Cancer Treated With Letrozole or Placebo After 5 Years of Tamoxifen: NCIC CTG Intergroup Trial MA.17  Journal Articles
• Emerging Biomarker-Guided Therapies in Prostate Cancer  Journal Articles
• Enantioselective Synthesis of Planar Chiral Ferrocifens that Show Chiral Discrimination in Antiproliferative Activity on Breast Cancer Cells  Journal Articles
• Endoplasmic Reticulum Chaperone Protein GRP78 Protects Cells from Apoptosis Induced by Topoisomerase Inhibitors  Journal Articles
• Engaging Patients in the Canadian Real-World Evidence for Value in Cancer Drugs (CanREValue) Initiative: Processes and Lessons Learned  Journal Articles
• Engaging specialist oncologists in the assessment of oncology drugs in Canada  Journal Articles
• Enzyme-responsive mannose-grafted magnetic nanoparticles for breast and liver cancer therapy and tumor-associated macrophage immunomodulation  Journal Articles
• Epidermal Growth Factor Receptor: Pathway, Therapies, and Pipeline  Journal Articles
• Epigenetic regulation of noncanonical menin targets modulates menin inhibitor response in acute myeloid leukemia.  Journal Articles
• Erythrocytotoxicity Induced by Cancer Chemotherapeutic Agents  Journal Articles
• Erythropoiesis-stimulating agents (ESAs): Do they still have a role in chemotherapy-induced anemia (CIA)?  Journal Articles
• Erythropoietin in the management of patients with nonhematologic cancer receiving chemotherapy. Systemic Treatment Program Committee.  Journal Articles
• Esophageal gastrointestinal stromal tumor: report of 7 patients  Journal Articles
• Essential medicines for cancer: WHO recommendations and national priorities  Journal Articles
• Essential medicines for children with cancer  Journal Articles
• Essential medicines for pediatric oncology in developing countries  Journal Articles
• Estrogen independent gene expression defines clinically relevant subgroups of estrogen receptor positive breast cancer  Journal Articles
• European oncologists' preferences for the management of breast cancer: case presentations and expert commentary  Journal Articles
• Evaluating Treatments for Childhood Cancer: A Process for Critical Appraisal of the Literature and a Summary of the Results  Journal Articles
• Evaluation of Adverse Events Experienced by Older Patients Participating in Studies of Molecularly Targeted Agents Alone or in Combination  Journal Articles
• Evaluation of Cognitive Function Associated With Chemotherapy: A Review of Published Studies and Recommendations for Future Research  Conferences
• Evaluation of metformin in early breast cancer: a modification of the traditional paradigm for clinical testing of anti-cancer agents  Journal Articles
• Evidence and values: requirements for public reimbursement of drugs for rare diseases--a case study in oncology.  Journal Articles
• Evidence for a dose-response effect between p53 (but not p21WAF1/Cip1) protein concentrations, survival, and responsiveness in patients with epithelial ovarian cancer treated with platinum-based chemotherapy.  Conferences
• Exacerbation of coagulopathy with concurrent bone marrow necrosis, hepatic and renal dysfunction secondary to all-trans retinoic acid therapy for acute promyelocytic leukemia  Journal Articles
• Experience with ponatinib in paediatric patients with leukaemia  Journal Articles
• Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging  Journal Articles
• Expression of delayed toxicity and lethal mutations in the progeny of human cells surviving exposure to radiation and other environmental mutagens  Conferences
• Expression of survivin and p16INK4a/Cdk6/pRB proteins and induction of apoptosis in response to radiation and cisplatin in meningioma cells  Journal Articles
• FEASIBILITY AND SAFETY OF FULL DOSE ANTICOAGULATION THERAPY (ACT) IN CHILDREN TREATED ACCORDING TO DANA-FARBER CANCER INSTITUTE (DFCI) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) CONSORTIUM THERAPY PROTOCOLS  Conferences
• Facile Construction of Structurally Diverse Thiazolidinedione-Derived Compounds via Divergent Stereoselective Cascade Organocatalysis and Their Biological Exploratory Studies  Journal Articles
• Failure of methylprednisolone acetate to prolong the antinauseant effect of intravenous methylprednisolone sodium succinate in patients receiving chemotherapy.  Journal Articles
• Fair, just and compassionate: A pilot for making allocation decisions for patients requesting experimental drugs outside of clinical trials  Journal Articles
• Feasibility and safety of delivering full‐dose anticoagulation therapy in children treated according to Dana‐Farber Cancer Institute acute lymphoblastic leukemia consortium therapy protocols  Journal Articles
• Feasibility of real time next generation sequencing of cancer genes linked to drug response: Results from a clinical trial  Journal Articles
• Fieber bei chemotherapie-assoziierter Neutropenie  Journal Articles
• First-Line Nivolumab in Stage IV or Recurrent Non–Small-Cell Lung Cancer  Journal Articles
• First-in-human phase I study of SOR-C13, a TRPV6 calcium channel inhibitor, in patients with advanced solid tumors  Journal Articles
• Flavopiridol Sensitivity of Cancer Cells Isolated from Ascites and Pleural Fluids  Journal Articles
• Flavopiridol in Untreated or Relapsed Mantle-Cell Lymphoma: Results of a Phase II Study of the National Cancer Institute of Canada Clinical Trials Group  Journal Articles
• Funding New Cancer Drugs in Ontario: Closing the Loop in the Practice Guidelines Development Cycle  Journal Articles
• Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells  Journal Articles
• Gemcitabine Plus Carboplatin Compared With Carboplatin in Patients With Platinum-Sensitive Recurrent Ovarian Cancer: An Intergroup Trial of the AGO-OVAR, the NCIC CTG, and the EORTC GCG  Journal Articles
• Gender and BCR‐ABL transcript type are correlated with molecular response to imatinib treatment in patients with chronic myeloid leukemia  Journal Articles
• Genome-Wide Associations and Functional Genomic Studies of Musculoskeletal Adverse Events in Women Receiving Aromatase Inhibitors  Journal Articles
• Glasgow Prognostic Score As a Prognostic Factor in Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel-Based Chemotherapy  Journal Articles
• Growth and body composition in response to chemotherapy in children with acute lymphoblastic leukemia  Journal Articles
• Growth inhibition of prostate cancer xenografts by halofuginone*†  Journal Articles
• Guideline for the prevention and treatment of anticipatory nausea and vomiting due to chemotherapy in pediatric cancer patients  Journal Articles
• Guidelines for vismodegib in the management of periocular basal cell carcinoma  Journal Articles
• HDAC inhibitor M344 suppresses MCF-7 breast cancer cell proliferation  Journal Articles
• HDACi Delivery Reprograms Tumor-Infiltrating Myeloid Cells to Eliminate Antigen-Loss Variants  Journal Articles
• HER2 Testing in a Population-Based Study of Patients With Metastatic Breast Cancer Treated With Trastuzumab  Journal Articles
• HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function  Journal Articles
• Helping Patients Make Informed Choices: A Randomized Trial of a Decision Aid for Adjuvant Chemotherapy in Lymph Node-Negative Breast Cancer  Journal Articles
• Hemostatic alterations in cancer patients  Journal Articles
• Heparin/heparan sulfate interacting protein plays a role in apoptosis induced by anticancer drugs  Journal Articles
• Herpes Zoster in Patients with Small-Cell Carcinoma of the Lung Receiving Combined Modality Treatment  Journal Articles
• Heterogeneity among lists of cautioned or prohibited drugs in protocols of early-phase oncology trials  Journal Articles
• Home chemotherapy for children with cancer: perspectives from health care professionals  Journal Articles
• Homocysteine and methylmalonic acid: markers to predict and avoid toxicity from pemetrexed therapy.  Journal Articles
• Hospital-acquired infections at an oncological intensive care cancer unit: differences between solid and hematological cancer patients  Journal Articles
• How I do it: Prescribing abiraterone acetate for metastatic castration resistant prostate cancer.  Journal Articles
• How Variable Is Our Delivery of Information? Approaches to Patient Education About Oral Chemotherapy in the Pediatric Oncology Clinic  Journal Articles
• Human cells deficient in transcription-coupled repair show prolonged activation of the Jun N-terminal kinase and increased sensitivity following cisplatin treatment  Journal Articles
• Hypercoagulability preceding cancer  Journal Articles
• Hypermagnesiuria and Hypercalciuria in Childhood Leukemia  Journal Articles
• Hypertension Due to Antiangiogenic Cancer Therapy With VEGF Inhibitors: Is Autonomic Nervous System Toxicity Another Possible Mechanism?  Journal Articles
• Identification of Drugs Including a Dopamine Receptor Antagonist that Selectively Target Cancer Stem Cells  Journal Articles
• Imaging Intratumoral Convection: Pressure-Dependent Enhancement in Chemotherapeutic Delivery to Solid Tumors  Journal Articles
• Imatinib Mesylate in Patients With Adenoid Cystic Cancers of the Salivary Glands Expressing c-kit: A Princess Margaret Hospital Phase II Consortium Study  Journal Articles
• Imatinib for Melanomas Harboring Mutationally Activated or Amplified KIT Arising on Mucosal, Acral, and Chronically Sun-Damaged Skin  Journal Articles
• Imipridone Anticancer Compounds Ectopically Activate the ClpP Protease and Represent a New Scaffold for Antibiotic Development  Journal Articles
• Immediate Post–Transurethral Resection of Bladder Tumor Intravesical Chemotherapy Prevents Non–Muscle-invasive Bladder Cancer Recurrences: An Updated Meta-analysis on 2548 Patients and Quality-of-Evidence Review  Journal Articles
• Immune-Checkpoint Induced Skin Toxicity Masked as Squamous Cell Carcinoma: Case Report on Mimickers of Dermatological Toxicity with PD-1 Inhibition  Journal Articles
• Immuno-Isolation in Oncology - A Mini-Review  Journal Articles
• Immunotherapy with rituximab during peripheral blood stem cell transplantation for non-Hodgkin's lymphoma  Journal Articles
• Impact and Perceptions of Mandatory Tumor Biopsies for Correlative Studies in Clinical Trials of Novel Anticancer Agents  Conferences
• Impact of Prior Platinum-Based Therapy on Patients Receiving Salvage Systemic Treatment for Advanced Urothelial Carcinoma  Journal Articles
• Impact of Response to Prior Chemotherapy in Patients With Advanced Urothelial Carcinoma Receiving Second-Line Therapy: Implications for Trial Design  Journal Articles
• Impact of a Novel Prioritization Framework on Clinician-Led Oncology Drug Submissions  Journal Articles
• Impact of baseline BMI and weight change in CCTG adjuvant breast cancer trials  Journal Articles
• Impact of chemotherapy-associated nausea and vomiting on patients' functional status and on costs: survey of five Canadian centres.  Journal Articles
• Impact of premenopausal status at breast cancer diagnosis in women entered on the placebo-controlled NCIC CTG MA17 trial of extended adjuvant letrozole  Journal Articles
• Improvements in Radiographic Progression-Free Survival Stratified by ERG Gene Status in Metastatic Castration-Resistant Prostate Cancer Patients Treated with Abiraterone Acetate  Journal Articles
• In Utero Exposure to Chemotherapy: Effect on Cardiac and Neurologic Outcome  Journal Articles
• In vitro antineoplastic effects of brivaracetam and lacosamide on human glioma cells  Journal Articles
• In vitro assessment of a gallium-doped glass polyalkenoate cement: chemotherapeutic potential, cytotoxicity and osteogenic effects  Journal Articles
• In vitro inhibition of proliferation of HL-60 cells by tetrandrine and coriolus versicolor peptide derived from Chinese medicinal herbs  Journal Articles
• Incidence of Metastatic Nonseminomatous Germ Cell Tumor Outside the Boundaries of a Modified Postchemotherapy Retroperitoneal Lymph Node Dissection  Journal Articles
• Incidence of second primary malignancies in patients with multiple myeloma receiving anti-CD38 monoclonal antibodies: A systematic review and meta-analysis  Journal Articles
• Incident Vertebral Fractures in Children With Leukemia During the Four Years Following Diagnosis  Journal Articles
• Inconsistency of prognostic factors for post-chemotherapy nausea and vomiting  Journal Articles
• Increasing the dose intensity of chemotherapy by more frequent administration or sequential scheduling: a patient-level meta-analysis of 37 298 women with early breast cancer in 26 randomised trials  Journal Articles
• Incremental net benefit in randomized clinical trials  Journal Articles
• Indirect comparison of the efficacy of cetuximab and cisplatin in squamous cell carcinoma of the head and neck  Journal Articles
• Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs  Journal Articles
• Induction chemotherapy with paclitaxel and cisplatin followed by radiotherapy for larynx organ preservation in advanced laryngeal and hypopharyngeal cancer offers moderate late toxicity outcome (DeLOS-I-trial)  Journal Articles
• Induction of Mdm2 and enhancement of cell survival by bFGF  Journal Articles
• Influence of the proto-oncogene c-fos on cisplatin sensitivity  Journal Articles
• Inhibition of p53 Transcriptional Activity by Bcl-2 Requires Its Membrane-anchoring Domain  Journal Articles
• Initial Management of Small-Cell Lung Cancer (limited- and Extensive-Stage) and the Role of Thoracic Radiotherapy and First-Line Chemotherapy: A Systematic Review  Journal Articles
• Initial characterization of an antineoplastic, polysaccharide-rich extract of Mycobacterium bovis BCG, Tice substrain.  Journal Articles
• Initiation of Chemotherapy in Cancer Patients with Poor Performance Status: A Population-Based Analysis  Journal Articles
• Innovative uses of imiquimod.  Journal Articles
• Integration of Bone and Computed Tomography Scans to Assess Bone Metastasis in Metastatic Castration-Resistant Prostate Cancer  Journal Articles
• Interactions of doxycycline with chemotherapeutic agents in human breast adenocarcinoma MDA-MB-231 cells  Journal Articles
• Interventions for the prevention of acute phase chemotherapy-induced nausea and vomiting in adult and pediatric patients: a systematic review and meta-analysis  Journal Articles
• Intraperitoneal chemotherapy in the first‐line treatment of women with stage III epithelial ovarian cancer  Journal Articles
• Intratumoral heterogeneity: pathways to treatment resistance and relapse in human glioblastoma  Journal Articles
• Intravenous PEG-asparaginase during remission induction in children and adolescents with newly diagnosed acute lymphoblastic leukemia  Journal Articles
• Intravenous and Oral Itraconazole versus Intravenous Amphotericin B Deoxycholate as Empirical Antifungal Therapy for Persistent Fever in Neutropenic Patients with Cancer Who Are Receiving Broad-Spectrum Antibacterial Therapy  Journal Articles
• Intravenous pegylated asparaginase versus intramuscular native Escherichia coli l-asparaginase in newly diagnosed childhood acute lymphoblastic leukaemia (DFCI 05-001): a randomised, open-label phase 3 trial  Journal Articles
• Investigating the potential clinical benefit of Selumetinib in resensitising advanced iodine refractory differentiated thyroid cancer to radioiodine therapy (SEL-I-METRY): protocol for a multicentre UK single arm phase II trial  Journal Articles
• Involvement of 1,25D3-MARRS (membrane associated, rapid response steroid-binding), a novel vitamin D receptor, in growth inhibition of breast cancer cells  Journal Articles
• Is SABR Cost-Effective in Oligometastatic Cancer? An Economic Analysis of the SABR-COMET Randomized Trial  Conferences
• Is There a Role for Positron Emission Tomography in Breast Cancer Staging?  Journal Articles
• Is There an Economic Rationale for Cancer Drugs to Have a Separate Reimbursement Review Process for Resource Allocation Purposes?  Journal Articles
• Isolation and Characterization of Novel Marine-Derived Actinomycete Taxa Rich in Bioactive Metabolites  Journal Articles
• Large Nontransplanted Hepatocellular Carcinoma in Woodchucks: Treatment With Adenovirus-Mediated Delivery of Interleukin 12/B7.1 Genes  Journal Articles
• Left and right ventricular effects of anthracycline and trastuzumab chemotherapy: A prospective study using novel cardiac imaging and biochemical markers  Journal Articles
• Lessons from assembling a microbial natural product and pre-fractionated extract library in an academic laboratory  Journal Articles
• Lessons learned from the Sunbelt Melanoma Trial  Journal Articles
• Leukemia after Chemotherapy for Cancer  Journal Articles
• Local tumour control in women with carcinoma of the cervix treated with the addition of nitroimidazole agents to radiotherapy: a meta-analysis  Journal Articles
• Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17  Journal Articles
• Long-Term Clinical Outcome After Postchemotherapy Retroperitoneal Lymph Node Dissection in Men With Residual Teratoma  Journal Articles
• Long-term gross motor performance following treatment for acute lymphoblastic leukemia  Journal Articles
• Long-term outcomes for neoadjuvant versus adjuvant chemotherapy in early breast cancer: meta-analysis of individual patient data from ten randomised trials  Journal Articles
• Lung cancer.  Journal Articles
• Lung cancer.  Journal Articles
• Lung cancer.  Journal Articles
• Major arterial events in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors: a meta-analysis  Journal Articles
• Management of advanced or recurrent cervical cancer: chemotherapy and beyond  Journal Articles
• Mathematical model for chemotherapeutic drug efficacy in arresting tumour growth based on the cancer stem cell hypothesis  Journal Articles
• Measuring the Quality of a Childhood Cancer Care Delivery System: Assessing Stakeholder Agreement  Journal Articles
• Mechanism and non-mechanism based imaging biomarkers for assessing biological response to treatment in non-small cell lung cancer  Journal Articles
• Mechanism of action of antimitotic drugs: A new hypothesis based on the role of cellular calcium  Journal Articles
• Mechanisms of Cardiovascular Toxicity of BCR-ABL1 Tyrosine Kinase Inhibitors in Chronic Myelogenous Leukemia  Journal Articles
• Medicines for cancers in children: The WHO model for selection of essential medicines  Journal Articles
• Melanoma in children and the use of sentinel lymph node biopsy  Conferences
• Melatonin as Adjuvant Cancer Care With and Without Chemotherapy  Journal Articles
• Meta-analysis: Effect of Prophylactic Hematopoietic Colony-Stimulating Factors on Mortality and Outcomes of Infection  Journal Articles
• Metabolic flexibility determines human NK cell functional fate in the tumor microenvironment  Journal Articles
• Metabolic response by FDG-PET to imatinib correlates with exon 11 KIT mutation and predicts outcome in patients with mucosal melanoma  Journal Articles
• Metabolomic adaptations and correlates of survival to immune checkpoint blockade  Journal Articles
• Metastatic renal cell cancer treatments: An indirect comparison meta-analysis  Journal Articles
• Metformin ameliorates arsenic trioxide hepatotoxicity via inhibiting mitochondrial complex I  Journal Articles
• Methods to improve the estimation of time‐to‐event outcomes when data is de‐identified  Journal Articles
• MicroRNA Signature in Metastatic Colorectal Cancer Patients Treated With Anti-EGFR Monoclonal Antibodies  Journal Articles
• Mitochondrial DNA damage by anticancer agents  Journal Articles
• Mitochondrial contributions to cancer cell physiology: potential for drug development  Journal Articles
• Mitochondrial contributions to cancer cell physiology: redox balance, cell cycle, and drug resistance.  Journal Articles
• Mixed Variant Multicentric Castleman Disease Treated With Rituximab: Case Report  Journal Articles
• Modulation of goldfish testicular testosterone production in vitro by tumor necrosis factor α, interleukin‐1β, and macrophage conditioned media  Journal Articles
• Monoamine oxidase inhibitors l-deprenyl and clorgyline protect nonmalignant human cells from ionising radiation and chemotherapy toxicity  Journal Articles
• Motexafin Gadolinium Combined With Prompt Whole Brain Radiotherapy Prolongs Time to Neurologic Progression in Non–Small-Cell Lung Cancer Patients With Brain Metastases: Results of a Phase III Trial  Journal Articles
• Mould-active compared with fluconazole prophylaxis to prevent invasive fungal diseases in cancer patients receiving chemotherapy or haematopoietic stem-cell transplantation: a systematic review and meta-analysis of randomised controlled trials  Journal Articles
• Moving promising research findings to the clinic: Methodological issues in the design and conduct of clinical trials of retinoids  Journal Articles
• Multitargeted Antifolate LY231514 as First-Line Chemotherapy for Patients With Advanced Non–Small-Cell Lung Cancer: A Phase II Study  Journal Articles
• Multitargeted anti-angiogenic agents and NSCLC: Clinical update and future directions  Journal Articles
• Multitargeting activity of miR-24 inhibits long-term melatonin anticancer effects  Journal Articles
• Muscle atrophy in cancer: a role for nutrition and exercise  Journal Articles
• Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy  Journal Articles
• Myasthenic syndrome and small cell cancer of the lung. Variable response to antineoplastic therapy.  Journal Articles
• Naturally occurring resistance of bone marrow mononuclear and metastatic cancer cells to anticancer agents  Journal Articles
• Neurite outgrowth in PC12 cells is enhanced by guanosine through both cAMP-dependent and -independent mechanisms  Journal Articles
• Neuropsychological outcomes of a randomized trial of prednisone versus dexamethasone in acute lymphoblastic leukemia: Findings from Dana-Farber Cancer Institute All Consortium Protocol 00-01  Journal Articles
• Next Wave of Targets in the Treatment of Advanced Renal Cell Carcinoma  Journal Articles
• Nitric oxide and anti-cancer therapy  Journal Articles
• Nivolumab Monotherapy for First-Line Treatment of Advanced Non–Small-Cell Lung Cancer  Journal Articles
• No. 370-Management of Squamous Cell Cancer of the Vulva  Journal Articles
• Non-chemotherapeutic agents that potentiate chemotherapy efficacy  Journal Articles
• Non-hormonal systemic therapy in men with hormone-refractory prostate cancer and metastases: a systematic review from the Cancer Care Ontario Program in Evidence-based Care's Genitourinary Cancer Disease Site Group  Journal Articles
• Non-melanoma Skin Cancer in Canada Chapter 3: Management of Actinic Keratoses  Journal Articles
• Noninvasive molecular imaging of apoptosis in vivo using a modified firefly luciferase substrate, Z-DEVD-aminoluciferin  Journal Articles
• Novel Treatments for Multiple Myeloma: What Role Do They Have in Older Adults?  Journal Articles
• Novel anticoagulant agents: introduction  Journal Articles
• Novel method for differentiation between Trastuzumab and host adaptive response  Journal Articles
• Novel strategies for systemic treatment of endometrial cancer  Journal Articles
• Novel targets and approaches in advanced prostate cancer  Journal Articles
• Nucleotide excision repair in the human ovarian carcinoma cell line (2008) and its cisplatin-resistant variant (C13*)  Journal Articles
• Nutritional status of children during treatment for acute lymphoblastic leukemia in Guatemala  Journal Articles
• Obstacles to effective Toll-like receptor agonist therapy for hematologic malignancies  Journal Articles
• Olaparib combined with chemotherapy for recurrent platinum-sensitive ovarian cancer: a randomised phase 2 trial  Journal Articles
• Olaparib in patients with recurrent high-grade serous or poorly differentiated ovarian carcinoma or triple-negative breast cancer: a phase 2, multicentre, open-label, non-randomised study  Journal Articles
• Olaparib tablets as maintenance therapy in patients with platinum-sensitive, relapsed ovarian cancer and a BRCA1/2 mutation (SOLO2/ENGOT-Ov21): a double-blind, randomised, placebo-controlled, phase 3 trial  Journal Articles
• Oligonucleotide degradation contributes to resistance to antisense compounds  Journal Articles
• Omics Underpins Novel Clues on VDR Chemoprevention Target in Breast Cancer  Journal Articles
• On the receiving end V: Patient perceptions of the side effects of cancer chemotherapy in 1993  Journal Articles
• Oncofertility  Journal Articles
• Oncostatin M Induces Bone Loss and Sensitizes Rat Osteosarcoma to the Antitumor Effect of MidostaurinIn vivo  Journal Articles
• Oncostatin M in combination with tumor necrosis factor α induces cartilage damage and matrix metalloproteinase expression in vitro and in vivo  Journal Articles
• Open-label comparison of the antiemetic efficacy of single intravenous doses of dolasetron mesylate in pediatric cancer patients receiving moderately to highly emetogenic chemotherapy  Journal Articles
• Opioids and Dose-Related Deaths—Association or Causation?  Journal Articles
• Osimertinib in UntreatedEGFR-Mutated Advanced Non–Small-Cell Lung Cancer  Journal Articles
• Osteonecrosis in children and adolescents with cancer – An adverse effect of systemic therapy  Journal Articles
• Osteopenia in children with acute lymphoblastic leukemia: A pilot study of amelioration with pamidronate  Journal Articles
• Outcomes in patients with advanced urothelial carcinoma after discontinuation of programmed death (PD)‐1 or PD ligand 1 inhibitor therapy  Journal Articles
• Overall Survival with Osimertinib in Untreated, EGFR-Mutated Advanced NSCLC  Journal Articles
• Overview of phase I studies of intravenous administration of PV701, an oncolytic virus.  Journal Articles
• PLATYPUS: A Multiple-View Learning Predictive Framework for Cancer Drug Sensitivity Prediction.  Journal Articles
• Pancratistatin induces apoptosis and autophagy in metastatic prostate cancer cells  Journal Articles
• Paraneoplastic Polyarthritis in Hepatocellular Carcinoma Treated With Lenvatinib  Journal Articles
• Patient Eligibility and Trial Design for the Salvage Therapy of Advanced Urothelial Carcinoma  Journal Articles
• Pattern of carboplatin-induced emesis  Journal Articles
• Pediatric oncology sedation trial (POST): A double‐blind randomized study  Journal Articles
• Pentostatin-induced hypereosinophilia with eosinophilic gastroenteritis  Journal Articles
• Perceived cognitive impairment in people with colorectal cancer who do and do not receive chemotherapy  Journal Articles
• Personalizing the Treatment of Pediatric Medulloblastoma: Polo-like Kinase 1 as a Molecular Target in High-Risk Children  Journal Articles
• Pharmacologic insights into the future of trastuzumab.  Conferences
• Pharmacotherapeutic management of asthma in pregnancy and the effect of sex hormones  Journal Articles
• Phase 2 Study of Acupuncture-Like Transcutaneous Nerve Stimulation for Chemotherapy-Induced Peripheral Neuropathy  Journal Articles
• Phase I Dose-Escalation Study of Linsitinib (OSI-906) and Erlotinib in Patients with Advanced Solid Tumors  Journal Articles
• Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of AGS15E Monotherapy in Patients with Metastatic Urothelial Carcinoma  Journal Articles
• Phase I clinical, pharmacokinetic and pharmacodynamic study of SB939, an oral histone deacetylase (HDAC) inhibitor, in patients with advanced solid tumours  Journal Articles
• Phase I dose-escalation study to determine the safety, pharmacokinetics and pharmacodynamics of brivanib alaninate in combination with full-dose cetuximab in patients with advanced gastrointestinal malignancies who have failed prior therapy  Journal Articles
• Phase I study of daily and weekly regimens of the orally administered MDM2 antagonist idasanutlin in patients with advanced tumors  Journal Articles
• Phase I trial of UCN-01 in combination with topotecan in patients with advanced solid cancers: a Princess Margaret Hospital Phase II Consortium study  Journal Articles
• Phase I trial of lonidamine with whole body hyperthermia in advanced cancer.  Journal Articles
• Phase I/II study of the deacetylase inhibitor panobinostat after allogeneic stem cell transplantation in patients with high-risk MDS or AML (PANOBEST trial)  Journal Articles
• Phase I/randomized phase II study of afatinib, an irreversible ErbB family blocker, with or without protracted temozolomide in adults with recurrent glioblastoma  Journal Articles
• Phase II Evaluation of Lonidamine in Patients with Advanced Malignancy  Journal Articles
• Phase II Stopping Rules That Employ Response Rates and Early Progression  Journal Articles
• Phase II Study of Erlotinib in Recurrent or Metastatic Endometrial Cancer: NCIC IND-148  Journal Articles
• Phase II Study of Temsirolimus in Women With Recurrent or Metastatic Endometrial Cancer: A Trial of the NCIC Clinical Trials Group  Journal Articles
• Phase II Study of Trimetrexate in Recurrent Anaplastic Glioma: National Cancer Institute of Canada Clinical Trials Group Study  Journal Articles
• Phase II Study of Troxacitabine (BCH-4556) in Patients with Advanced Non-Small-Cell Lung Cancer  Journal Articles
• Phase II Trial of N,N-Diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine.HCl and Doxorubicin Chemotherapy in Metastatic Breast Cancer: A National Cancer Institute of Canada Clinical Trials Group Study  Journal Articles
• Phase II Trial of Sorafenib in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck or Nasopharyngeal Carcinoma  Conferences
• Phase II study of TAS‐106 in patients with platinum‐failure recurrent or metastatic head and neck cancer and nasopharyngeal cancer  Journal Articles
• Phase II study of CGP 69846A (ISIS 5132) in recurrent epithelial ovarian cancer: an NCIC clinical trials group study (NCIC IND.116)☆  Journal Articles
• Phase II study of Triapine® in patients with metastatic renal cell carcinoma: a trial of the National Cancer Institute of Canada Clinical Trials Group (NCIC IND.161)  Journal Articles
• Phase II study of amonafide: results of treatment and lessons learned from the study of an investigational agent in previously untreated patients with extensive small-cell lung cancer.  Journal Articles
• Phase II study of erlotinib (OSI-774) in patients with metastatic colorectal cancer  Journal Articles
• Phase II study of ispinesib in recurrent or metastatic squamous cell carcinoma of the head and neck  Conferences
• Phase II study of oral ridaforolimus in women with recurrent or metastatic endometrial cancer  Journal Articles
• Phase II study of temsirolimus (CCI-779) in women with recurrent, unresectable, locally advanced or metastatic carcinoma of the cervix. A trial of the NCIC Clinical Trials Group (NCIC CTG IND 199)  Journal Articles
• Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma  Journal Articles
• Phase II trial of the histone deacetylase inhibitor belinostat in women with platinum resistant epithelial ovarian cancer and micropapillary (LMP) ovarian tumours  Journal Articles
• Phase II trial of vorinostat in advanced melanoma  Journal Articles
• Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix.  Journal Articles
• Phase III trial to evaluate the efficacy of maintaining hemoglobin levels above 12.0 g/dL with erythropoietin vs above 10.0 g/dL without erythropoietin in anemic patients receiving concurrent radiation and cisplatin for cervical cancer  Journal Articles
• Phosphopeptide Selective Coordination Complexes as Promising Src Homology 2 Domain Mimetics  Journal Articles
• Photobleaching kinetics of Photofrinin vivoand in multicell tumour spheroids indicate two simultaneous bleaching mechanisms  Journal Articles
• Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain  Journal Articles
• Physician/Patient Decision Aids for Adjuvant Therapy  Journal Articles
• Pin1 Links the Activities of c-Abl and p300 in Regulating p73 Function  Journal Articles
• Plant-Produced Trastuzumab Inhibits the Growth of HER2 Positive Cancer Cells  Journal Articles
• Pneumatosis Intestinalis and Bowel Perforation Associated With Molecular Targeted Therapy: An Emerging Problem and the Role of Radiologists in Its Management  Journal Articles
• Point/counterpoint: early-stage Hodgkin lymphoma and the role of radiation therapy.  Journal Articles
• Pointed Progress in Second-Line Advanced Non–Small-Cell Lung Cancer: The Rapidly Evolving Field of Checkpoint Inhibition  Journal Articles
• Poly(ethylene glycol) induces cell toxicity in melanoma cells by producing a hyperosmotic extracellular medium  Journal Articles
• Pooled safety analysis of BAY 43-9006 (sorafenib) monotherapy in patients with advanced solid tumours: Is rash associated with treatment outcome?  Journal Articles
• Population-Based Study to Determine the Health System Costs of Using the 21-Gene Assay  Journal Articles
• Predicting Teratoma in the Retroperitoneum in Men Undergoing Post-Chemotherapy Retroperitoneal Lymph Node Dissection  Journal Articles
• Predicting response to EGFR-tyrosine kinase inhibitors among diverse ancestries: Just way too polymorphic  Journal Articles
• Preferential Killing of Breast Tumor Initiating Cells by N,N-Diethyl-2-[4-(Phenylmethyl)Phenoxy]Ethanamine/Tesmilifene  Journal Articles
• Prevention and treatment of anticipatory chemotherapy‐induced nausea and vomiting in pediatric cancer patients and hematopoietic stem cell recipients: Clinical practice guideline update  Journal Articles
• Prevention of Thrombosis in Ambulatory Patients With Cancer  Journal Articles
• Prevention of Thrombotic Disorders in Cancer Patients Undergoing Chemotherapy  Journal Articles
• Prevention of acute and delayed chemotherapy‐induced nausea and vomiting in pediatric cancer patients: A clinical practice guideline  Journal Articles
• Primary tumor and patient characteristics in breast cancer as predictors of adjuvant therapy regimen: a regression model  Journal Articles
• Prognosis of older patients with newly diagnosed AML undergoing antileukemic therapy: A systematic review  Journal Articles
• Prognostic Factors in the Radical Nonsurgical Treatment of Stage IIIB Non–Small-Cell Lung Cancer  Journal Articles
• Prognostic nomogram to predict progression-free survival in patients with platinum-sensitive recurrent ovarian cancer  Journal Articles
• Prolonged complete remission in two cases of acute promyelocytic leukaemia treated with atra alone  Journal Articles
• Prophage induction by N-methyl-N'-nitro-N-nitrosoguanidine.  Journal Articles
• Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 Trial  Journal Articles
• Prospective evaluation of pretreatment and intratreatment FDG PET‐CT SUV stability in primary head and neck cancer  Journal Articles
• Proteasome Inhibition With Bortezomib (PS-341): A Phase I Study With Pharmacodynamic End Points Using a Day 1 and Day 4 Schedule in a 14-Day Cycle  Journal Articles
• Protumorigenic effects of mir-145 loss in malignant pleural mesothelioma  Journal Articles
• Pt(iv) antitumor prodrugs: dogmas, paradigms, and realities  Journal Articles
• Pyrimethamine as a Potent and Selective Inhibitor of Acute Myeloid Leukemia Identified by High-throughput Drug Screening  Journal Articles
• Pyrvinium Targets CD133 in Human Glioblastoma Brain Tumor–Initiating Cells  Journal Articles
• Quality of Life in a Prospective, Multicenter Phase 2 Trial of Neoadjuvant Full-Dose Gemcitabine, Oxaliplatin, and Radiation in Patients With Resectable or Borderline Resectable Pancreatic Adenocarcinoma  Journal Articles
• Quality of life and swallowing with standard chemoradiotherapy versus accelerated radiotherapy and panitumumab in locoregionally advanced carcinoma of the head and neck: A phase III randomised trial from the Canadian Cancer Trials Group (HN.6)  Journal Articles
• Quality of life in stage II breast cancer: an instrument for clinical trials.  Journal Articles
• Quality-adjusted life years was a poor predictor of women's willingness to pay in acute and chronic conditions: results of a survey  Journal Articles
• Quality-of-Life Measurement in Randomized Clinical Trials in Breast Cancer: An Updated Systematic Review (2001–2009)  Journal Articles
• Quantification of matrix metalloproteinase activity in plasma of patients enrolled in a BAY 12-9566 phase I study  Journal Articles
• Quantitative evaluation of single-arm versus randomized phase II cancer clinical trials  Journal Articles
• Quinolone-Based Antibacterial Chemoprophylaxis in Neutropenic Patients: Effect of Augmented Gram-Positive Activity on Infectious Morbidity  Journal Articles
• Quizartinib for the treatment of acute myeloid leukemia  Journal Articles
• Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck  Journal Articles
• Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival  Journal Articles
• Raloxifene, a Mixed Estrogen Agonist/Antagonist, Induces Apoptosis through Cleavage of BAD in TSU-PR1 Human Cancer Cells  Journal Articles
• Randomized Phase II Study Comparing Two Schedules of Everolimus in Patients With Recurrent/Metastatic Breast Cancer: NCIC Clinical Trials Group IND.163  Conferences
• Randomized Trial of a Telephone-Based Weight Loss Intervention in Postmenopausal Women With Breast Cancer Receiving Letrozole: The LISA Trial  Journal Articles
• Randomized Trials in Oncology Stopped Early for Benefit  Journal Articles
• Randomized window of opportunity trial evaluating high-dose vitamin D in breast cancer patients  Journal Articles
• Rash in four patients with brain tumor-related epilepsy in monotherapy with oxcarbazepine, during radiotherapy  Journal Articles
• Real world data on outcomes of anti-CD38 antibody treated, including triple class refractory, patients with multiple myeloma: a multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database  Journal Articles
• Real-World Use of Trifluridine/Tipiracil for Patients with Metastatic Colorectal Cancer in Canada  Journal Articles
• Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations  Journal Articles
• Reduced Morbidity Following Cytoreductive Surgery and Intraperitoneal Hyperthermic Chemoperfusion  Conferences
• Reduced tissue macrophage population in the lung by anticancer agent cyclophosphamide: restoration by local granulocyte macrophage–colony-stimulating factor gene transfer  Journal Articles
• Reduction in local recurrence and improved survival in surgically treated patients with small cell lung cancer  Journal Articles
• Refinement of the Symptom Screening in Pediatrics Tool (SSPedi)  Journal Articles
• Regional Nodal Irradiation in Early-Stage Breast Cancer  Journal Articles
• Relevant clinical end points in biphosphonate trials.  Journal Articles
• Renal failure among multiple myeloma patients utilizing carfilzomib and associated factors in the “real world”  Journal Articles
• Repurposed AT9283 triggers anti-tumoral effects by targeting MKK3 oncogenic functions in Colorectal Cancer.  Journal Articles
• Researching the Cost of Research  Journal Articles
• Response to Suissa and Azoulay. The Association of Basal Insulin Glargine and/or n-3 Fatty Acids With Incident Cancers in Patients With Dysglycemia. Diabetes Care 2014;37:1360–1366  Journal Articles
• Response to Zanders et al. The Association of Basal Insulin Glargine and/or n-3 Fatty Acids With Incident Cancers in Patients With Dysglycemia. Diabetes Care 2014;37:1360–1366  Journal Articles
• Results of the SEL-I-METRY Phase II Trial on Resensitization of Advanced Iodine Refractory Differentiated Thyroid Cancer to Radioiodine Therapy  Journal Articles
• Retinoic acid and arsenic trioxide sensitize acute promyelocytic leukemia cells to ER stress  Journal Articles
• Review of Cytotoxic CA4 Analogues that Do Not Target Microtubules: Implications for CA4 Development.  Journal Articles
• Ribbon of DNA Lattice on Gold Nanoparticles for Selective Drug Delivery to Cancer Cells  Journal Articles
• Risk factors for survival following recurrence after first liver resection for colorectal cancer liver metastases  Journal Articles
• Risk of Thrombosis With Lenalidomide and Its Prevention With Aspirin  Journal Articles
• Rituximab in Lymphoma and Chronic Lymphocytic Leukaemia: A Practice Guideline  Journal Articles
• Rituximab in lymphoma: A systematic review and consensus practice guideline from Cancer Care Ontario  Journal Articles
• Rituximab maintenance for relapsed refractory thrombotic thrombocytopenic purpura  Journal Articles
• Rivaroxaban for Thromboprophylaxis in High-Risk Ambulatory Patients with Cancer  Journal Articles
• Robot-assisted Versus Open Radical Cystectomy in Patients Receiving Perioperative Chemotherapy for Muscle-invasive Bladder Cancer: The Oncologist’s Perspective from a Multicentre Study  Journal Articles
• Rodlike Particles of Polydopamine-CdTe Quantum Dots: An Actuator As a Photothermal Agent and Reactive Oxygen Species-Generating Nanoplatform for Cancer Therapy  Journal Articles
• Rolapitant for the Treatment of Chemotherapy-Induced Nausea and Vomiting: A Review of the Clinical Evidence  Journal Articles
• Role of KRAS and EGFR As Biomarkers of Response to Erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21  Journal Articles
• Role of the transcription factor Ets-1 in cisplatin resistance  Journal Articles
• Safety and Efficacy of Patupilone in Patients With Advanced Ovarian, Primary Fallopian, or Primary Peritoneal Cancer: A Phase I, Open-Label, Dose-Escalation Study  Journal Articles
• Safety and Efficacy of Sorafenib in Elderly Patients Treated in the North American Advanced Renal Cell Carcinoma Sorafenib Expanded Access Program  Journal Articles
• Safety and efficacy findings from the open-label, multicenter, phase 3b, expanded treatment protocol study of ruxolitinib for treatment of patients with polycythemia vera who are resistant/intolerant to hydroxyurea and for whom no alternative treatments are available  Journal Articles
• Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America  Journal Articles
• Safety of Treatment of Metastatic Breast Cancer With Trastuzumab Beyond Disease Progression  Journal Articles
• Safety of enzalutamide in patients with metastatic castration‐resistant prostate cancer previously treated with docetaxel: Expanded access in North America  Journal Articles
• Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Sorafenib: A Review of Four Phase I Trials in Patients with Advanced Refractory Solid Tumors  Journal Articles
• Sample size and power issues in estimating incremental cost-effectiveness ratios from clinical trials data  Journal Articles
• Second-Line Treatment of Non-Small Cell Lung Cancer: New Developments for Tumours Not Harbouring Targetable Oncogenic Driver Mutations  Journal Articles
• Second‐line treatment of hepatocellular carcinoma after sorafenib: Characterizing treatments used over the past 10 years and real‐world eligibility for cabozantinib, regorafenib, and ramucirumab  Journal Articles
• Semuloparin for Thromboprophylaxis in Patients Receiving Chemotherapy for Cancer  Journal Articles
• Sequential preoperative fluorodeoxyglucose-positron emission tomography assessment of response to preoperative chemoradiation: a means for determining longterm outcomes of rectal cancer1  Conferences
• Serotonergic system antagonists target breast tumor initiating cells and synergize with chemotherapy to shrink human breast tumor xenografts  Journal Articles
• Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies  Journal Articles
• Single-center experience with radium-223 in patients with castration-resistant prostate cancer and bone metastases  Journal Articles
• Skeletal Muscle Depletion Is Associated with Reduced Plasma (n-3) Fatty Acids in Non-Small Cell Lung Cancer Patients  Journal Articles
• Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects  Journal Articles
• Soft-Tissue Necrosis Induced by Extravasated Cancer Chemotherapeutic Agents2, 3  Journal Articles
• Sorafenib Maintenance After Allogeneic Hematopoietic Stem Cell Transplantation for Acute Myeloid Leukemia With FLT3–Internal Tandem Duplication Mutation (SORMAIN)  Journal Articles
• Sorafenib and Radiation Therapy for the Treatment of Advanced Hepatocellular Carcinoma  Journal Articles
• Spleen effluent manipulations  Journal Articles
• Statement of the Science Concerning Locoregional Treatments After Preoperative Chemotherapy for Breast Cancer: A National Cancer Institute Conference  Journal Articles
• Statin Therapy and Outcomes in Trials of Nintedanib in Idiopathic Pulmonary Fibrosis  Journal Articles
• Statin Use and Survival in Patients with Metastatic Castration-resistant Prostate Cancer Treated with Abiraterone Acetate  Journal Articles
• Statin therapy in the treatment of active cancer: A systematic review and meta-analysis of randomized controlled trials  Journal Articles
• Stopping rules employing response rates, time to progression, and early progressive disease for phase II oncology trials  Journal Articles
• Stressproteine bei der Pathogenese des Prostatakarzinoms  Journal Articles
• Structurally simplified biphenyl combretastatin A4 derivatives retain in vitro anti-cancer activity dependent on mitotic arrest  Journal Articles
• Structure-activity studies on N -Substituted tranylcypromine derivatives lead to selective inhibitors of lysine specific demethylase 1 (LSD1) and potent inducers of leukemic cell differentiation  Journal Articles
• Structure–activity studies on seco-pancratistatin analogs: Potent inhibitors of human cytochrome P450 3A4  Journal Articles
• Sulfasalazine‐induced cystine starvation: Potential use for prostate cancer therapy  Journal Articles
• Superantigen immune stimulation activates epithelial STAT-1 and PI 3-K: PI 3-K regulation of permeability  Journal Articles
• Superiority of methylprednisolone sodium succinate over low dose metoclopramide hydrochloride in the prevention of nausea and vomiting produced by cancer chemotherapy.  Journal Articles
• Sustained activation of the extracellular signal-regulated kinase pathway protects cells from photofrin-mediated photodynamic therapy.  Journal Articles
• Sustained deep molecular responses in patients switched to nilotinib due to persistent BCR-ABL1 on imatinib: final ENESTcmr randomized trial results  Journal Articles
• Symptom clusters using the Brief Pain Inventory in patients with breast cancer  Journal Articles
• Synthesis and Biological Evaluation of Fully Functionalized seco-Pancratistatin Analogues  Journal Articles
• Synthesis and Evaluation of Anticancer Natural Product Analogues Based on Angelmarin: Targeting the Tolerance towards Nutrient Deprivation  Journal Articles
• Synthesis and characterization of cyclohexane-1R,2R-diamine-based Pt(iv) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines  Journal Articles
• Synthesis and evaluation of new salicylaldehyde-2-picolinylhydrazone Schiff base compounds of Ru(II), Rh(III) and Ir(III) as in vitro antitumor, antibacterial and fluorescence imaging agents  Journal Articles
• Synthesis and structure-activity relationships among glycosidic derivatives of 4'-demethylepipodophyllotoxin and epipodophyllotoxin, showing VM26- and VP16-213-like activities.  Journal Articles
• Synthesis of Boroxifen, A Nido-Carborane Analogue of Tamoxifen  Journal Articles
• Synthesis, characterization, structure, molecular modeling studies and biological activity of sterically crowded Pt(II) complexes containing bis(imidazole) ligands  Journal Articles
• Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol  Journal Articles
• Systemic Therapy for Previously Untreated Advanced BRAF -Mutated Melanoma: Navigating a Shifting Landscape  Journal Articles
• Systemic Therapy for Stage IV Non–Small-Cell Lung Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update  Journal Articles
• Systemic treatments for metastatic urothelial carcinoma  Journal Articles
• TLE3 is not a predictive biomarker for taxane sensitivity in the NCIC CTG MA.21 clinical trial  Journal Articles
• Targeted Drug Delivery Using a Plug-to-Direct Antibody–Nanogel Conjugate  Journal Articles
• Targeted and Non-Targeted Mechanisms for Killing Hypoxic Tumour Cells—Are There New Avenues for Treatment?  Journal Articles
• Targeted radionuclide therapy in combined-modality regimens  Journal Articles
• Targeted therapy for metastatic renal cell carcinoma  Journal Articles
• Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics  Journal Articles
• Targeting endothelin 1 receptor-miR-200b/c-ZEB1 circuitry blunts metastatic progression in ovarian cancer  Journal Articles
• Targeting of human cancer stem cells predicts efficacy and toxicity of FDA-approved oncology drugs  Journal Articles
• Targeting prostate cancer with HTI‐286, a synthetic analog of the marine sponge product hemiasterlin  Journal Articles
• Targeting the epidermal growth factor receptor in non-small-cell lung cancer: Who, which, when, and how?  Journal Articles
• Teclistamab in Relapsed or Refractory Multiple Myeloma  Journal Articles
• Teclistamab in Relapsed or Refractory Multiple Myeloma. Reply.  Journal Articles
• Telomerase, Cell Immortality, and Cancer  Journal Articles
• The Antiarrhythmic Drug, Dronedarone, Demonstrates Cytotoxic Effects in Breast Cancer Independent of Thyroid Hormone Receptor Alpha 1 (THRα1) Antagonism  Journal Articles
• The Association of Basal Insulin Glargine and/or n-3 Fatty Acids With Incident Cancers in Patients With Dysglycemia  Journal Articles
• The CANMAT task force recommendations for the management of patients with mood disorders and comorbid medical conditions: diagnostic, assessment, and treatment principles.  Journal Articles
• The Cancer-associated K351N Mutation Affects the Ubiquitination and the Translocation to Mitochondria of p53 Protein  Journal Articles
• The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: Rationale and design of the database and the collection of evidence available at approval of novel drugs  Journal Articles
• The Completeness of Reporting (CORE) index identifies important deficiencies in observational study conference abstracts  Journal Articles
• The Cost-Effectiveness of Lenvatinib in the Treatment of Advanced or Unresectable Hepatocellular Carcinoma from a Canadian Perspective  Journal Articles
• The Impact of Chemotherapy-Induced Cognitive Impairment on the Psychosocial Adjustment of Patients With Nonmetastatic Colorectal Cancer  Journal Articles
• The Price We Pay for Progress: A Meta-Analysis of Harms of Newly Approved Anticancer Drugs  Journal Articles
• The Prognostic Importance of Metastatic Site in Men with Metastatic Castration-resistant Prostate Cancer  Journal Articles
• The Silence in Hoch et al.’s Commentary about the Rationale for and Objective(s) of Canada’s Separate HTA Process for Cancer Drugs: The Importance of Transparency and Accountability when Allocating Taxpayers’ Dollars  Journal Articles
• The Thrombophilic State Induced by Therapeutic Agents in the Cancer Patient  Journal Articles
• The Urgent Need for Clinical Research Reform to Permit Faster, Less Expensive Access to New Therapies for Lethal Diseases  Journal Articles
• The Voice of Experience: Diet and Weight Change in Women with Breast Cancer Associate with Psychosocial and Treatment-Related Challenges  Journal Articles
• The arotinoids: early clinical experience and discussion of future development.  Journal Articles
• The association between radiographic response and overall survival in men with metastatic castration‐resistant prostate cancer receiving chemotherapy  Journal Articles
• The chemotherapy metabolite acrolein upregulates thrombin generation and impairs the protein C anticoagulant pathway in animal‐based and cell‐based models  Journal Articles
• The current role of anti-emetic drugs in oncology: a recent revolution in patient symptom control  Journal Articles
• The disruption of the protein complex mutantp53/p73 increases selectively the response of tumor cells to anticancer drugs  Journal Articles
• The effect of lonidamine alone and in combination with cisplatin on in vitro growth and viability of lung squamous cell carcinoma cell lines.  Journal Articles
• The effects of chemotherapeutic agents on the regulation of thrombin on cell surfaces  Journal Articles
• The efficacy and safety of sunitinib given on an individualised schedule as first-line therapy for metastatic renal cell carcinoma: A phase 2 clinical trial  Journal Articles
• The emerging treatment landscape of advanced urothelial carcinoma  Journal Articles
• The enzyme-sensitive release of prodigiosin grafted β-cyclodextrin and chitosan magnetic nanoparticles as an anticancer drug delivery system: Synthesis, characterization and cytotoxicity studies  Journal Articles
• The impact of an educational DVD on cancer patients considering participation in a phase I clinical trial  Journal Articles
• The impact of postchemotherapy nausea and vomiting on quality of life after moderately emetogenic chemotherapy  Journal Articles
• The impact of ruxolitinib on thrombosis in patients with polycythemia vera and myelofibrosis  Journal Articles
• The in vitro effects of lonidamine combined with cisplatin in human small cell lung cancer cell lines.  Journal Articles
• The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors  Journal Articles
• The international scandal of defective asparaginase: A blight on children with cancer  Journal Articles
• The low incidence of secondary acute myelogenous leukaemia in children and adolescents treated with dexrazoxane for acute lymphoblastic leukaemia: A report from the Dana-Farber Cancer Institute ALL Consortium  Journal Articles
• The oncolytic adenovirus AdΔΔ enhances selective cancer cell killing in combination with DNA-damaging drugs in pancreatic cancer models  Journal Articles
• The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway  Journal Articles
• The role of chemotherapy in invasive thymoma: a review of the literature and considerations for future clinical trials  Journal Articles
• The role of dose intensity in determining outcome in intermediate-grade non-Hodgkin's lymphoma.  Journal Articles
• The treatment of acute myelocytic leukemia in patients 30 years of age and younger  Journal Articles
• The triponderal mass index as a measure of adiposity in pediatric survivors of acute lymphoblastic leukemia: a cross-sectional study  Journal Articles
• The use of gemcitabine in non-small-cell lung cancer. Provincial Lung Cancer Disease Site Group. Provincial Systemic Treatment Disease Site Group.  Journal Articles
• Therapeutic Options for Neuroendocrine Tumors  Journal Articles
• Therapy for relapsed multiple myeloma  Journal Articles
• Therapy-naïve malignancy causes cardiovascular disease: a state-of-the-art cardio-oncology perspective  Journal Articles
• Thiazolidinedione drugs down-regulate CXCR4 expression on human colorectal cancer cells in a peroxisome proliferator activated receptor γ-dependent manner  Journal Articles
• Thromboembolic events in patients with urothelial carcinoma undergoing neoadjuvant chemotherapy and radical cystectomy  Journal Articles
• Thrombosis and cancer: implications beyond Trousseau  Journal Articles
• Thrombosis in children with acute lymphoblastic leukemia  Journal Articles
• Tolerability and efficacy of docetaxel in older men with metastatic castrate-resistant prostate cancer (mCRPC) in the TAX 327 trial  Journal Articles
• Transformation of the Anticancer Drug Doxorubicin in the Human Gut Microbiome  Journal Articles
• Transfusion‐related alloimmunization in children: epidemiology and effects of chemotherapy  Journal Articles
• Trastuzumab Cardiac Side Effects: Only Time Will Tell  Journal Articles
• Treatment and Clinical Outcomes of Patients with Teratoma with Somatic-Type Malignant Transformation: An International Collaboration  Journal Articles
• Treatment of Hormone-Refractory Prostate Cancer with Docetaxel or Mitoxantrone: Relationships between Prostate-Specific Antigen, Pain, and Quality of Life Response and Survival in the TAX-327 Study  Journal Articles
• Treatment of Venous Thromboembolism in Cancer Patients  Journal Articles
• Treatment of breakthrough and prevention of refractory chemotherapy‐induced nausea and vomiting in pediatric cancer patients: Clinical practice guideline update  Journal Articles
• Treatment of mCRPC in the AR-axis-targeted therapy-resistant state  Conferences
• Treatment of recurrent small cell lung cancer  Journal Articles
• Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy  Journal Articles
• Truncated ring-A amaryllidaceae alkaloid modulates the host cell integrated stress response, exhibiting antiviral activity to HSV-1 and SARSCoV-2  Journal Articles
• Tubular Injury Biomarkers to Predict CKD and Hypertension at 3 Months Post-Cisplatin in Children  Journal Articles
• USP2a alters chemotherapeutic response by modulating redox  Journal Articles
• Ultrasound Imaging of Apoptosis: Spectroscopic Detection of DNA-Damage Effects In Vivo  Journal Articles
• Unresected stage III non-small-cell lung cancer. Provincial Lung Cancer Disease Site Group.  Journal Articles
• Up-to-date approach to manage keloids and hypertrophic scars: A useful guide  Journal Articles
• Upper Tract Urothelial Carcinomas: Prognostic Factors and Outcomes in Patients With Non–Lymph Node Distant Metastasis  Journal Articles
• Up‐regulation of PK11195 binding in areas of axonal degeneration coincides with early microglial activation in mouse brain  Journal Articles
• Urothelial Bladder Cancer with Cavitary Lung Metastases  Journal Articles
• Use of Molecular Biomarkers to Quantify the Spatial Distribution of Effects of Anticancer Drugs in Solid Tumors  Journal Articles
• Use of dexamethasone and granisetron in the control of delayed emesis for patients who receive highly emetogenic chemotherapy. National Cancer Institute of Canada Clinical Trials Group.  Journal Articles
• Use of granulocyte colony-stimulating factor (G-CSF) in patients receiving myelosuppressive chemotherapy for the treatment of cancer. Provincial Systemic Treatment Disease Site Group.  Journal Articles
• Using Data From Ontario’s Episode-Based Funding Model to Assess Quality of Chemotherapy  Journal Articles
• Using bevacizumab to treat metastatic cancer: UK consensus guidelines  Journal Articles
• Value assessment of oncology drugs using a weighted criterion‐based approach  Journal Articles
• Variation in the Association between Antineoplastic Therapies and Venous Thromboembolism in Patients with Active Cancer  Journal Articles
• Veliparib in Combination with Carboplatin and Etoposide in Patients with Treatment-Naïve Extensive-Stage Small Cell Lung Cancer: A Phase 2 Randomized Study  Journal Articles
• Venetoclax for the treatment of translocation (11;14) AL amyloidosis  Journal Articles
• Venous Thromboembolism in Malignancy and Malignancy in Venous Thromboembolism  Journal Articles
• Very low-quality evidence suggests that aloe vera could have benefits in preventing chemotherapy-induced oral mucositis in children compared with sodium bicarbonate  Journal Articles
• Vinblastine‐Induced Erythrocytotoxicity  Journal Articles
• Weekly Cyclophosphamide and Alternate-Day Prednisone: An Effective, Convenient, and Well-Tolerated Oral Treatment for Relapsed Multiple Myeloma After Autologous Stem Cell Transplantation  Journal Articles
• Zoledronic acid is superior to pamidronate for the treatment of bone metastases in breast carcinoma patients with at least one osteolytic lesion  Journal Articles
• [ ¹⁸ F]CFA as a clinically translatable probe for PET imaging of deoxycytidine kinase activity  Journal Articles
• miR-204 targets Bcl-2 expression and enhances responsiveness of gastric cancer  Journal Articles
• p73-Mediated Chemosensitivity: A Preferential Target of Oncogenic Mutant p53  Journal Articles
• β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer  Journal Articles