Pt(iv) antitumor prodrugs: dogmas, paradigms, and realities Journal Articles

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abstract

Pt(IV) complexes are promising antitumor prodrugs releasing active Pt(II) moieties. Multi-functional Pt(IV) complexes contain two or more synergistic moieties. Many Pt(IV) prodrugs show encouraging pharmacological profiles.

authors

Ravera, Mauro
Gabano, Elisabetta
Mcglinchey, Michael James
Osella, Domenico

publication date

February 8, 2022

has subject area

0302 Inorganic Chemistry (FoR)
0307 Theoretical and Computational Chemistry (FoR)
0399 Other Chemical Sciences (FoR)
Animals (MeSH)
Antineoplastic Agents (MeSH)
Humans (MeSH)
Inorganic & Nuclear Chemistry (Science Metrix)
Neoplasms (MeSH)
Organoplatinum Compounds (MeSH)
Prodrugs (MeSH)

published in

Dalton Transactions Journal