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Cost Effectiveness of EML4-ALK Fusion Testing and...
Journal article

Cost Effectiveness of EML4-ALK Fusion Testing and First-Line Crizotinib Treatment for Patients With Advanced ALK-Positive Non–Small-Cell Lung Cancer

Abstract

PURPOSE: ALK-targeted therapy with crizotinib offers significant improvement in clinical outcomes for the treatment of EML4-ALK fusion-positive non-small-cell lung cancer (NSCLC). We estimated the cost effectiveness of EML4-ALK fusion testing in combination with targeted first-line crizotinib treatment in Ontario. PATIENTS AND METHODS: A cost-effectiveness analysis was conducted using a Markov model from the Canadian Public health (Ontario) …

Authors

Djalalov S; Beca J; Hoch JS; Krahn M; Tsao M-S; Cutz J-C; Leighl NB

Journal

Journal of Clinical Oncology, Vol. 32, No. 10, pp. 1012–1019

Publisher

American Society of Clinical Oncology (ASCO)

Publication Date

April 1, 2014

DOI

10.1200/jco.2013.53.1186

ISSN

0732-183X