Erythrocytotoxicity Induced by Cancer Chemotherapeutic Agents Journal Articles

abstract

• Increased osmotic fragility and methaemoglobin generation in vitro have resulted from the exposure of normal human erythrocytes to numerous cancer chemotherapeutic agents. These findings offer a possible explanation for the earlier, consistent clinical observation of the rapid development of anaemia, during consolidation therapy, in children with acute lymphoblastic leukaemia in remission.

authors

• Barr, Ronald Duncan
• Davidson, Alan R
• Jung, Lawrence KL
• Pai, KR Mohan

status

• published 

publication date

• August 1981

has subject area

• 1102 Cardiorespiratory Medicine and Haematology (FoR)
• Adult (MeSH)
• Antineoplastic Agents (MeSH)
• Erythrocytes (MeSH)
• Humans (MeSH)
• Immunology (Science Metrix)
• In Vitro Techniques (MeSH)
• Methemoglobin (MeSH)
• Osmotic Fragility (MeSH)

published in

• European Journal of Haematology  Journal

keywords

• Adult
• Antineoplastic Agents
• Erythrocytes
• Humans
• In Vitro Techniques
• Methemoglobin
• Osmotic Fragility

Digital Object Identifier (DOI)

• 10.1111/j.1600-0609.1981.tb01415.x

PubMed ID

• 7209404

start page

• 363

end page

• 368

volume

• 25

issue

• 4