Experts has a new look! Let us know what you think of the updates.

Provide feedback
Home
Scholarly Works
Adjunctive therapy (whole body hyperthermia versus...
Journal article

Adjunctive therapy (whole body hyperthermia versus lonidamine) to total body irradiation for the treatment of favorable b-cell neoplasms: a report of two pilot clinical trials and laboratory investigations

Abstract

Based on earlier clinical and preclinical investigations, we designed two different pilot trials for patients with nodular lymphoma or chronic lymphocytic leukemia. These studies evaluated the use of either 41.8 degrees C whole body hyperthermia (WBH), or the nonmyelosuppressive chemotherapeutic drug, lonidamine (LON), as an adjunct to total body irradiation (TBI) (12.5 cGy twice a week, every other week for a planned total dose of 150 cGy). …

Authors

Robins HI; Longo WL; Steeves RA; Cohen JD; Schmitt CL; Neville AJ; O'Keefe S; Lagoni R; Riggs C

Journal

International Journal of Radiation Oncology • Biology • Physics, Vol. 18, No. 4, pp. 909–920

Publisher

Elsevier

Publication Date

April 1990

DOI

10.1016/0360-3016(90)90416-h

ISSN

0360-3016