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Targeted radionuclide therapy in combined-modality...
Journal article

Targeted radionuclide therapy in combined-modality regimens

Abstract

Targeted radionuclide therapy (TRT) is a branch of cancer medicine concerned with the use of radioisotopes, radiolabelled molecules, nanoparticles, or microparticles that either naturally accumulate in or are designed to target tumours. TRT combines the specificity of molecular and sometimes physical targeting with the potent cytotoxicity of ionising radiation. Targeting vectors for TRT include antibodies, antibody fragments, proteins, …

Authors

Gill MR; Falzone N; Du Y; Vallis KA

Journal

The Lancet Oncology, Vol. 18, No. 7, pp. e414–e423

Publisher

Elsevier

Publication Date

July 2017

DOI

10.1016/s1470-2045(17)30379-0

ISSN

1470-2045