Vinblastine‐Induced Erythrocytotoxicity Journal Articles

abstract

• At a therapeutic concentration (10−6 mol/l), vinblastine causes no significant changes of erythrocyte morphology in whole blood in vitro, but, with 30% red cell suspensions in buffer, the drug is stomatocytogenic. Several pathogenetic mechanisms are considered and the clinical relevance of this finding is assessed.

authors

• Neville, Alan
• Rand, Carol A
• Barr, Ronald Duncan

status

• published 

publication date

• January 1982

has subject area

• 1102 Cardiorespiratory Medicine and Haematology (FoR)
• Adult (MeSH)
• Antineoplastic Agents (MeSH)
• Cells, Cultured (MeSH)
• Dose-Response Relationship, Drug (MeSH)
• Erythrocytes (MeSH)
• Humans (MeSH)
• Immunology (Science Metrix)
• Vinblastine (MeSH)

published in

• European Journal of Haematology  Journal

keywords

• Adult
• Antineoplastic Agents
• Cells, Cultured
• Dose-Response Relationship, Drug
• Erythrocytes
• Humans
• Vinblastine

Digital Object Identifier (DOI)

• 10.1111/j.1600-0609.1982.tb02117.x

PubMed ID

• 7071515

start page

• 32

end page

• 38

volume

• 28

issue

• 1