abstract
-
Cyclohexane-1
R ,2R -diamine carrier ligand increases the selectivity towards colon cancer cells with respect to diamines in asymmetrical (acetato)(carboxylato)platinum(iv ) prodrugs.
Synthesis and characterization of cyclohexane-1R,2R-diamine-based Pt(iv ) dicarboxylato anticancer prodrugs: their selective activity against human colon cancer cell lines
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authors
publication date
- January 2, 2019
has subject area
- 0302 Inorganic Chemistry (FoR)
- 0307 Theoretical and Computational Chemistry (FoR)
- 0399 Other Chemical Sciences (FoR)
- Antineoplastic Agents (MeSH)
- Cell Line, Tumor (MeSH)
- Cell Proliferation (MeSH)
- Colonic Neoplasms (MeSH)
- Drug Stability (MeSH)
- Humans (MeSH)
- Inhibitory Concentration 50 (MeSH)
- Inorganic & Nuclear Chemistry (Science Metrix)
- Molecular Structure (MeSH)
- Organoplatinum Compounds (MeSH)
- Prodrugs (MeSH)
- Solubility (MeSH)
published in
- Dalton Transactions Journal