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In Vitro Models to Compare the Duration of Action...
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In Vitro Models to Compare the Duration of Action of New Therapeutic Scaffolds and Drug Eluting Medical Devices

Abstract

Local therapies are in development for targeting of brain tumors and cancer stem cells, as well as non-brain tumors, due to significant transport barriers that hinder sufficient drug accumulation at the disease site. For chemotherapeutics, local delivery is already a well-established practice in the clinic for brain tumors. For immunotherapy applications, local therapies can include the delivery of immune cell engagers, adoptive cell therapies, …

Authors

Wai K; Wylie RG

Book title

Brain Tumor Stem Cells

Series

Methods in Molecular Biology

Volume

2944

Pagination

pp. 193-206

Publisher

Springer Nature

Publication Date

2025

DOI

10.1007/978-1-0716-4654-0_16