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Efficacy and Safety of Gemcitabine Plus Either...
Journal article

Efficacy and Safety of Gemcitabine Plus Either Taxane or Carboplatin in the First-Line Setting of Metastatic Urothelial Carcinoma: A Systematic Review and Meta-Analysis

Abstract

Although gemcitabine plus carboplatin (GCa) is the conventional first-line chemotherapy for cisplatin-ineligible metastatic urothelial carcinoma, its results are suboptimal. A meta-analysis evaluated the results of gemcitabine with either carboplatin or a taxane (GT). Literature was searched for studies including GT (paclitaxel or docetaxel) and GCa. We pooled trial level data including response-rate, progression-free survival, overall survival …

Authors

Necchi A; Pond GR; Raggi D; Giannatempo P; Vogelzang NJ; Grivas P; Galsky MD; Bellmunt J; Sonpavde G

Journal

Clinical Genitourinary Cancer, Vol. 15, No. 1, pp. 23–30.e2

Publisher

Elsevier

Publication Date

February 2017

DOI

10.1016/j.clgc.2016.05.003

ISSN

1558-7673