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Comparison of three assays for genetic effects of...
Journal article

Comparison of three assays for genetic effects of antineoplastic drugs on cancer patients and their nurses

Abstract

Three assays have been compared for their ability to detect genetic damage caused by antineoplastic drugs in cancer patients and possible damage in the nurses who administered these drugs. The assays were sister chromatid exchanges (SCE) and chromosomal aberrations in peripheral blood lymphocytes, and the Salmonella/mammalian microsome assay on urine. Three comparisons were made: 1) patients before versus after treatment; 2) the administering …

Authors

Krepinsky A; Bryant DW; Davison L; Young B; Heddle J; McCalla DR; Douglas G; Michalko K

Journal

Environmental and Molecular Mutagenesis, Vol. 15, No. 2, pp. 83–92

Publisher

Wiley

Publication Date

January 1990

DOI

10.1002/em.2850150205

ISSN

0893-6692