Journal article
Thrombosis in children with acute lymphoblastic leukemia Part II. Pathogenesis of thrombosis in children with acute lymphoblastic leukemia: effects of the disease and therapy
Abstract
At diagnosis, there is evidence of increased thrombin generation in children with acute lymphoblastic leukemia (ALL), the etiology of which is unclear. However, thromboembolism (TE) in children with ALL is most commonly reported after the initiation of antileukemic therapy indicating a possible interaction of the disease and therapy. Antileukemic therapy influences the haemostatic system either by direct effect of the chemotherapeutic agents or …
Authors
Athale UH; Chan AKC
Journal
Thrombosis Research, Vol. 111, No. 4-5, pp. 199–212
Publisher
Elsevier
Publication Date
January 2003
DOI
10.1016/j.thromres.2003.10.007
ISSN
0049-3848