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Novel targets and approaches in advanced prostate...
Journal article

Novel targets and approaches in advanced prostate cancer

Abstract

PURPOSE OF REVIEW: The development of therapeutic resistance is the underlying cause for most cancer deaths. By understanding the molecular basis of resistance to androgen withdrawal and chemotherapy in prostate cancer, the rational design of targeted therapeutics is possible. We review new treatment options for men with advanced prostate cancer. RECENT FINDINGS: Although the taxanes currently represent the most active chemotherapeutic agents …

Authors

Hadaschik BA; Sowery RD; Gleave ME

Journal

Current Opinion in Urology, Vol. 17, No. 3, pp. 182–187

Publisher

Wolters Kluwer

Publication Date

May 2007

DOI

10.1097/mou.0b013e3280dd8a4f

ISSN

0963-0643