Journal article
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
Abstract
BACKGROUND: We conducted a multinational, randomized study to compare radiotherapy alone with radiotherapy plus cetuximab, a monoclonal antibody against the epidermal growth factor receptor, in the treatment of locoregionally advanced squamous-cell carcinoma of the head and neck.
METHODS: Patients with locoregionally advanced head and neck cancer were randomly assigned to treatment with high-dose radiotherapy alone (213 patients) or high-dose …
Authors
Bonner JA; Harari PM; Giralt J; Azarnia N; Shin DM; Cohen RB; Jones CU; Sur R; Raben D; Jassem J
Journal
New England Journal of Medicine, Vol. 354, No. 6, pp. 567–578
Publisher
Massachusetts Medical Society
Publication Date
February 9, 2006
DOI
10.1056/nejmoa053422
ISSN
0028-4793