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Statin Therapy and Outcomes in Trials of...
Journal article

Statin Therapy and Outcomes in Trials of Nintedanib in Idiopathic Pulmonary Fibrosis

Abstract

BACKGROUND: Cardiovascular comorbidities are frequent in patients with idiopathic pulmonary fibrosis (IPF), and many patients with IPF receive treatment with statins to reduce cardiovascular risk. OBJECTIVES: We investigated whether statin use at baseline was associated with differences in disease progression in placebo-treated patients or influenced the treatment effect of nintedanib in the INPULSIS® trials.

Authors

Kreuter M; Costabel U; Richeldi L; Cottin V; Wijsenbeek M; Bonella F; Bendstrup E; Maher TM; Wachtlin D; Stowasser S

Journal

Respiration, Vol. 95, No. 5, pp. 317–326

Publisher

Karger Publishers

Publication Date

2018

DOI

10.1159/000486286

ISSN

0025-7931