Journal article
An Increase in Cellular Size Variance Contributes to the Increase in Ultrasound Backscatter During Cell Death
Abstract
This study aims to explain the contribution of changes in cellular size variance (CSV) to increases in ultrasound-integrated backscatter (UIB) measured from cell samples undergoing cell death. A Monte Carlo algorithm was used to compare simulations of 2D distributions of cells, uniform (CSV = 0) versus heterogeneous (CSV > 0) and the same mean cellular size (M ). UIB increased in arrangements with heterogeneous cellular sizes from 3.6dB (M = 20 …
Authors
Vlad RM; Saha RK; Alajez NM; Ranieri S; Czarnota GJ; Kolios MC
Journal
Ultrasound in Medicine & Biology, Vol. 36, No. 9, pp. 1546–1558
Publisher
Elsevier
Publication Date
September 2010
DOI
10.1016/j.ultrasmedbio.2010.05.025
ISSN
0301-5629